Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Preparation and physico-chemical characterization of transfection carriers based on polycationic surfactants.

2016/23/N/ST4/01637

Keywords:

siRNA gene therapy transfection polycationic surfactants

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_7: Electrochemistry, microfluidics in chemistry, sensors
  • ST4_13: Solid-state chemistry, surface physicochemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Weronika Andrzejewska 

Number of co-investigators in the project: 3

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 148 800 PLN

Project start date (Y-m-d): 2017-09-27

Project end date (Y-m-d): 2021-09-26

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komora laminarna z wyposażeniem do przeprowadzania testów na kulturach komórkowych. (18 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Ammonium Gemini Surfactants Form Complexes with Model Oligomers of siRNA and dsDNA
    Authors:
    Andrzejewska Weronika, Wilkowska Michalina, Skrzypczak Andrzej, Kozak Maciej
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20, strony: 5546-5564), Wydawca: Molecular Diversity Preservation International (MDPI)
    Status:
    Published
    DOI:
    10.3390/ijms20225546 - link to the publication
  2. Structural characterization of transfection nanosystems based on tricationic surfactants and short double stranded oligonucleotides.
    Authors:
    Andrzejewska Weronika, Wilkowska Michalina, Peplińska Barbara, Skrzypczak Andrzej, Kozak Maciej
    Academic press:
    Biochemical and Biophysical Research Communications (rok: 2019, tom: 518, strony: 706-711), Wydawca: Elsevier Inc.
    Status:
    Published
    DOI:
    10.1016/j.bbrc.2019.08.114. - link to the publication

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