Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Tecto-RNA nano-structures for gene expression regulation in a model system

2015/19/B/ST5/03087

Keywords:

RNA RNAi siRNA gene expresion regulation tecto-RNA

Descriptors:

  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials
  • ST5_16:
  • NZ3_14: Other related subjects

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Arkadiusz Chworoś 

Number of co-investigators in the project: 3

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 668 500 PLN

Project start date (Y-m-d): 2016-07-14

Project end date (Y-m-d): 2020-07-13

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Stanowisko komputerowe wraz z oprogramowaniem (10 515 PLN)
  2. Mikroskop fluorescencyjny (34 000 PLN)
  3. Thermomixer Comfort.
  4. bioanalizator (124 000 PLN)
  5. licznik komórek (12 800 PLN)
  6. termocykler (36 500 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Highly Fluorescent Distyrylnaphthalene Derivatives as a Tool for Visualization of Cellular Membranes
    Authors:
    Justyna Suwara, Beata Lukasik, Remigiusz Zurawinski, Roza Pawlowska and Arkadiusz Chworos
    Academic press:
    Materials (rok: 2020, tom: 13, strony: 45311), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13040951 - link to the publication
  2. Self-Assembling RNA Nanoparticle for Gene Expression Regulation in a Model System
    Authors:
    Dominika Jedrzejczyk, Arkadiusz Chworos
    Academic press:
    ACS Synth. Biol. (rok: 2019, tom: 8, strony: 491-497), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acssynbio.8b00319 - link to the publication
  3. Gold nanoparticles as carriers for functional RNA nanostructures
    Authors:
    Anna Graczyk, Roza Pawlowska, Arkadiusz Chworos
    Academic press:
    Bioconjugate Chemistry , Wydawca: American Chemical Society
    Status:
    Submitted
    DOI:
    brak - link to the publication
  4. Designing synthetic RNA for delivery by nanoparticles
    Authors:
    Dominika Jedrzejczyk, Edyta Gendaszewska-Darmach, Roza Pawlowska and Arkadiusz Chworos
    Academic press:
    J. Phys.: Condens. Matter (rok: 2017, tom: 29, strony: 123001), Wydawca: IOP
    Status:
    Published
    DOI:
    10.1088/1361-648X/aa5561 - link to the publication
  5. Gold Nanoparticles in Conjunction with Nucleic Acids as a Modern Molecular System for Cellular Delivery
    Authors:
    Anna Graczyk, Roza Pawlowska, Dominika Jedrzejczyk and Arkadiusz Chworos
    Academic press:
    Molecules (rok: 2020, tom: 25, strony: 45318), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules25010204 - link to the publication

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