Projects funded by the NCN


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115 projects found matching your search criteria :

  1. Role of sirtuin 2 (SIRT2) in the drug resistance of melanomas.

    Call: OPUS 9 , Panel: NZ5

    Principal investigator: dr Marcin Marek Ratajewski

    Instytut Biologii Medycznej PAN

  2. DNA repair pathways contributing to resistance to photodynamic therapy and as possible theraupeutic targets

    Call: OPUS 8 , Panel: NZ5

    Principal investigator: dr hab. Elżbieta Speina

    Instytut Biochemii i Biofizyki PAN

  3. Search for early molecular mechanisms and markers of preclinical stage of sporadic form of Alzheimer's disease (SAD) in ...

    Call: SONATA 8 , Panel: NZ4

    Principal investigator: dr Anna Mietelska-Porowska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  4. Transcriptional regulation of selected PKB/Akt and their significance in insulin sesitivity control of peripheral tissue...

    Call: OPUS 8 , Panel: NZ5

    Principal investigator: prof. Dariusz Kazimierz Moczulski

    Uniwersytet Medyczny w Łodzi, Katedra Chorób Wewnętrznych i Kardiologii, Klinika Chorób Wewnętrznych i Nefrodiabetologii

  5. Identification of new, clinically relevant genetic and epigenetic aberrations by next-generation sequencing in chronic m...

    Call: HARMONIA 6 , Panel: NZ5

    Principal investigator: dr Tomasz Artur Stokłosa

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  6. L-asparaginase resistance in childhood ALL with IKZF1, TP53, BCR-ABL1 and iAMP21 alterations.

    Call: PRELUDIUM 7 , Panel: NZ5

    Principal investigator: Ewa Karolina Wrona

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  7. Cancer stem cells signaling pathways as a therapeutic terget in ovarian cancer chemotherapy

    Call: OPUS 7 , Panel: NZ5

    Principal investigator: prof. Maciej Zabel

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

  8. Evaluation of the contribution of telomerase regulation with TMPyP4 and cisplatin to multidrug resistance in breast canc...

    Call: PRELUDIUM 7 , Panel: NZ7

    Principal investigator: dr Natalia Konieczna

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny, Katedra i Zakład Chemii Klinicznej i Diagnostyki Molekularnej

  9. Analysis of the mechanism of the photodynamic inactivation of Candida albicans with the use of novel photosensitizing ag...

    Call: PRELUDIUM 5 , Panel: NZ1

    Principal investigator: dr Aleksandra Taraszkiewicz

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  10. Metabolic derangements and skeletal muscle performance in men with advanced systolic heart failure

    Call: PRELUDIUM 5 , Panel: NZ5

    Principal investigator: Michał Tkaczyszyn

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Nauk o Zdrowiu

  11. Investigation of mechanisms of leptin-resistance induced by pregnancy in sheep

    Call: OPUS 5 , Panel: NZ4

    Principal investigator: dr Małgorzata Ewa Szczęsna

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Hodowli i Biologii Zwierząt

  12. The study of mechanisms of corrsion erosion resistance of composite coatings with additions of metallic particles.

    Call: OPUS 4 , Panel: ST8

    Principal investigator: dr Marzanna Maria Książek

    Sieć Badawcza ŁUKASIEWICZ - Instytut Odlewnictwa

  13. Genetic mechanisms of drug resisntance in breast cancer patients treated with 5-fluorouracil, doxorubicine and cyclophos...

    Call: PRELUDIUM 4 , Panel: NZ5

    Principal investigator: dr Karolina Halina Tęcza

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie Oddział w Gliwicach

  14. The relationship between plasma visfatin concentration and components of the metabolic syndrome and the factors influenc...

    Call: OPUS 4 , Panel: NZ5

    Principal investigator: prof. Jerzy Chudek

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Lekarski w Katowicach

  15. The role of sirtuins and AMPK protein kinase in insulin resistance of podocytes

    Call: OPUS 3 , Panel: NZ5

    Principal investigator: dr Dorota Rogacka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  16. Molecular mechanisms of multidrug resistance to synthetic fungicides in fungi of the Fusarium genus

    Call: SONATA 2 , Panel: NZ9

    Principal investigator: dr Delfina Popiel

    Instytut Genetyki Roślin PAN

  17. Understanding the co-selection mechanisms of antibiotic and heavy metal resistance during methane fermentation of sewage...

    Call: OPUS 28 , Panel: NZ9

    Principal investigator: dr Małgorzata Czatzkowska

    Uniwersytet Warmińsko-Mazurski w Olsztynie

  18. Could fibroblast senescence and their resistance to apoptosis be the hidden drivers behind endometrial fibrosis in equin...

    Call: OPUS 28 , Panel: NZ5

    Principal investigator: dr Katarzyna Karolina Piotrowska-Tomala

    Instytut Rozrodu Zwierząt i Badań Żywności PAN

  19. Factors associated with a modulation of fibrin clot structure and resistance to fibrinolysis in patients with protein C ...

    Call: OPUS 28 , Panel: NZ5

    Principal investigator: dr hab. Michał Tomasz Ząbczyk

    Krakowski Szpital Specjalistyczny im. Jana Pawła II

  20. Mechanisms of Antidepressant Action of Psilocybin: The Role of 5-HT2B-5-HT1A Receptor Dimerization and GSK-3β Activation...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr hab. Agata Faron-Górecka

    Instytut Farmakologii PAN

  21. Precision double strike against non-small cell lung cancer. Insights into multidirectional therapies and the landscape o...

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr Katarzyna Anna Malarz

    Politechnika Śląska

  22. Evaluation of the relationship between doxorubicin resistance, epithelial-mesenchymal plasticity, and effects of selecte...

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Dominika Kunachowicz

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

  23. Evaluation of the role of miRNA as a peripheral biomarker of drug resistance in epilepsy using biosensors for electroche...

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr hab. Janusz Szyndler

    Warszawski Uniwersytet Medyczny

  24. Impact of cytostatic drugs present in the environment on Gram-negative bacteria: mechanisms of adaptation and implicatio...

    Call: PRELUDIUM 23 , Panel: NZ9

    Principal investigator: Adam Grzywaczyk

    Politechnika Poznańska

  25. Potential and mechanisms changes in antibiotic susceptibility in Listeria monocytogenes under pascalisation-induced stre...

    Call: PRELUDIUM 23 , Panel: NZ9

    Principal investigator: Patryk Wiśniewski

    Uniwersytet Warmińsko-Mazurski w Olsztynie

  26. Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii PAN

  27. Mitochondria-related mechanisms of exosome biogenesis and secretion in podocytes under metabolic stress.

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr Irena Audzeyenka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  28. The sinonasal microbiome - temporal dynamics and alterations caused by selective antibiotic pressure.

    Call: SONATA 19 , Panel: NZ5

    Principal investigator: dr Joanna Agnieszka Szaleniec

    Uniwersytet Jagielloński, Collegium Medicum

  29. Strategies to improve the efficacy of NK cells in targeting aggressive B-cell lymphomas

    Call: WEAVE-UNISONO , Panel: NZ6

    Principal investigator: dr Małgorzata Bobrowicz

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  30. Development of high entropy alloys with high radiation resistance and elevated mechanical properties at high temperature...

    Call: SONATA BIS 13 , Panel: ST11

    Principal investigator: dr hab. Łukasz Ryszard Kurpaska

    Narodowe Centrum Badań Jądrowych

  31. Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Anna Krętowska-Grunwald

    Uniwersytet Medyczny w Białymstoku

  32. Cuproptosis, a novel pathway of regulated cell death as a therapeutic target in treatment-naïve and targeted therapy-res...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: dr hab. Mariusz Łukasz Hartman

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  33. Studies on the growth mechanisms of multiphase protective scales on selected groups of high-temperature materials using ...

    Call: OPUS 25 , Panel: ST11

    Principal investigator: dr Maciej Bik

    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Inżynierii Materiałowej i Ceramiki

  34. Beyond antibiotic resistance. Towards better understanding the process of awakening of uropathogenic E. coli persister c...

    Call: SONATINA 7 , Panel: NZ1

    Principal investigator: dr Marcin Jan Równicki

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

  35. Dinucleoside polyphosphates (NpnN′s) as a component of the molecular mechanism in plant response to environmental stress...

    Call: OPUS 24 , Panel: NZ9

    Principal investigator: dr hab. Małgorzata Pietrowska-Borek

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Biotechnologii

  36. Mechanism of action of b-cyclocitral and its derivative in inducing flax resistance to Fusarium oxysporum infection

    Call: OPUS 24 , Panel: NZ9

    Principal investigator: dr Aleksandra Anna Boba

    Uniwersytet Wrocławski, Wydział Biotechnologii

  37. Targeted poloxamer micelles with selected drugs as a strategy for overcoming the mechanisms of multidrug resistance in p...

    Call: PRELUDIUM BIS 4 , Panel: NZ7

    Principal investigator: prof. Tomasz Adam Gośliński

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  38. Searching for new chemical compounds inducing resistance of apple to diseases and determination of the molecular mechani...

    Call: SONATA 18 , Panel: NZ9

    Principal investigator: dr Artur Mikiciński

    Instytut Ogrodnictwa

  39. The significance of Zc3h12a gene deletion in hepatocytes and proximal tubular epithelial cells for neoplastic transforma...

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr Paulina Marona

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  40. Role of the PARP1/HPF1 complex in the conferring of resistance to doxorubicin in triple negative breast cancer

    Call: PRELUDIUM 21 , Panel: NZ5

    Principal investigator: Magdalena Alicja Strachowska

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  41. Molecular mechanisms underlying resistance of white lupin (Lupinus albus L.) to anthracnose

    Call: OPUS 23 , Panel: NZ9

    Principal investigator: dr hab. Michał Piotr Książkiewicz

    Instytut Genetyki Roślin PAN

  42. New strategy for overcoming resistance to chemotherapy of ovarian cancer by modulation of the canonical and non-canonica...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr hab. Radosław Januchowski

    Uniwersytet Zielonogórski, Collegium Medicum

  43. Brain GABAB receptors as determinants of obesity phenotypes: evaluation of adolescent female and male rats

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii PAN

  44. The role of Candida albicans' plasma membrane sphingolipids in the potentially new mechanism of drug resistance and in t...

    Call: OPUS 22 , Panel: NZ1

    Principal investigator: dr hab. Anna Janina Krasowska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  45. Improving the fracture resistance of forging medium manganese steel understatic, dynamic and cyclic loading conditions b...

    Call: OPUS 22 (LAP) , Panel: ST5

    Principal investigator: prof. Adam Szczepan Grajcar

    Politechnika Śląska, Wydział Mechaniczny Technologiczny

  46. Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr hab. Carlo Vascotto

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  47. CRISPRi-based screening for Pseudomonas aeruginosa vulnerabilities to antibiotics

    Call: SONATA 17 , Panel: NZ2

    Principal investigator: dr Adam Kawałek

    Instytut Biochemii i Biofizyki PAN

  48. Nanospectroscopic imaging of native biological membranes: Is the cell membrane the key for understanding the mechanism o...

    Call: SONATA BIS 11 , Panel: ST4

    Principal investigator: dr Katarzyna Pogoda

    Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego PAN

  49. Molecular and functional characterisation of clubroot disease resistance mechanisms in Arabidopsis

    Call: OPUS 21 , Panel: NZ9

    Principal investigator: dr William Matthew Donald Truman

    Instytut Genetyki Roślin PAN

  50. Analysis of semaphorin 3 (SEMA3), protocadherin 9 (PCDH9) and S 100 calcium binding proteinA3 (S100A3) expression in pro...

    Call: OPUS 21 , Panel: NZ5

    Principal investigator: dr hab. Radosław Januchowski

    Uniwersytet Zielonogórski, Collegium Medicum