Projects funded by the NCN


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115 projects found matching your search criteria :

  1. Evaluation of NOTCH1- and NOTCH3-dependent anticancer drug resistance in a 2D and 3D model of Head and Neck Squamous Cel...

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: dr Joanna Elżbieta Kałafut

    Uniwersytet Medyczny w Lublinie

  2. Elucidation of the role of miR-7-5p in modulating of multidrug resistance in glioblastoma cells.

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: dr Ewa Lucyna Gajda

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

  3. Verification of personalized therapeutic strategy based on Integrated Stress Response inhibition for myeloid neoplasms w...

    Call: OPUS 21 , Panel: NZ5

    Principal investigator: dr hab. Katarzyna Piwocka

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  4. Reversible senescence as a new mechanism of cancer cell resistance for chemotherapy. Analysis of the mechanism of cancer...

    Call: SONATINA 5 , Panel: NZ3

    Principal investigator: dr Karolina Anna Staniak

    Politechnika Warszawska, Wydział Chemiczny

  5. The role of vitamin D receptor in 5-fluorouracil responsiveness of colorectal cancer cells

    Call: SONATA 16 , Panel: NZ5

    Principal investigator: dr Magdalena - Milczarek

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  6. Novel dual CYP17A1 and AKR1C3 inhibitors for studying the mechanism of resistance in prostate cancer

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Tomasz Marcin Wróbel

    Uniwersytet Medyczny w Lublinie

  7. Array-based genomic and transcriptomic profiling in pediatric acute myeloblastic leukemia in search of genes resposible ...

    Call: SONATA 2 , Panel: NZ5

    Principal investigator: dr Joanna Szczepanek

    Uniwersytet Mikołaja Kopernika

  8. Research on the influence of self-healing, organic-inorganic sol-gel layers on the corrosion resistance and fatigue of s...

    Call: OPUS 20 (LAP) , Panel: ST5

    Principal investigator: dr Justyna Krzak

    Politechnika Wrocławska

  9. Study on genetic, epigenetic, transcriptomic and proteomic mechanisms modulating sheep resistance to small ruminant lent...

    Call: OPUS 20 (LAP) , Panel: NZ9

    Principal investigator: dr hab. Ewa Joanna Grochowska

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

  10. Histological and structural remodeling of mitral valve chordae tendineae and the traction resistance in aspect of the pr...

    Call: PRELUDIUM BIS 2 , Panel: NZ5

    Principal investigator: prof. Agnieszka - Noszczyk-Nowak

    Uniwersytet Przyrodniczy we Wrocławiu

  11. Changes in lipid metabolism of resistant to BRAF/MEK inhibitors human melanoma cells associated with the presence of adi...

    Call: SONATA 16 , Panel: NZ5

    Principal investigator: dr Aleksandra Simiczyjew

    Uniwersytet Wrocławski, Wydział Biotechnologii

  12. Zinc deficient diet as a trigger for treatment-resistant depression in chronically stressed mice. Understanding the mech...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: dr hab. Bernadeta Szewczyk

    Instytut Farmakologii PAN

  13. Mechanism of acquiring resistance to polyenes on the Malassezia pachydermatis model

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Urszula Czyżewska

    Uniwersytet w Białymstoku, Wydział Biologii

  14. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii PAN

  15. The significance of mitochondrial DNA damage and reapir in occurance of insulin resistance in nonalcoholic fatty liver d...

    Call: PRELUDIUM BIS 1 , Panel: NZ5

    Principal investigator: prof. Janusz Zbigniew Szemraj

    Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

  16. Analysis of bacteriophage P1 lytic functions as a way to discover the mechanisms of wide dissemination of clinical bacte...

    Call: PRELUDIUM 18 , Panel: NZ6

    Principal investigator: Agnieszka Bednarek

    Instytut Biochemii i Biofizyki PAN

  17. Investigation of the effectiveness and mechanisms of fungicidal activity of selected 1,3,4-thiadiazoles derivatives in i...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Mariusz Gagoś

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

  18. Galactosylceramide as a regulator of apoptotic gene expression and modulator of drug resistance in breast cancer cells.

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: prof. Maciej Ugorski

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Medycyny Weterynaryjnej

  19. Gankyrin protein as a new potential therapeutic target in multiple myeloma

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr hab. Irena Misiewicz-Krzemińska

    Instytut Hematologii i Transfuzjologii

  20. Elucidation of the mechanism of fat-induced liver insulin resistance

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: dr hab. Agnieszka Urszula Błachnio-Zabielska

    Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

  21. Potential function of visfatin/NAMPT in the anoikis resistance of human ovarian cancer: novel insight into obesity-reala...

    Call: PRELUDIUM 17 , Panel: NZ5

    Principal investigator: dr Justyna Karolina Gogola-Mruk

    Uniwersytet Jagielloński, Wydział Biologii

  22. Determination of the mechanisms and possibility of central nervous system regeneration using mesenchymal stem cells and ...

    Call: OPUS 16 , Panel: NZ3

    Principal investigator: prof. Marcin Marek Majka

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum

  23. Identifying and overcoming mechanisms promoting resistance to venetoclax in B cell acute lymphoblastic leukemia with MLL...

    Call: PRELUDIUM 16 , Panel: NZ5

    Principal investigator: dr Klaudyna Paulina Fidyt

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  24. The significance of cancer specific PFK-II (PFKFB3 and PFKFB4) isoenzymes inhibition in overcoming resistance to BRAF in...

    Call: PRELUDIUM 16 , Panel: NZ5

    Principal investigator: Sonia Elżbieta Trojan

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum

  25. The combination of radiotherapy with imiquimod and sunitinib as a new therapeutic strategy overcoming some of the tumor ...

    Call: SONATA 14 , Panel: NZ5

    Principal investigator: dr Magdalena Jarosz-Biej

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

  26. Dissecting of the novel mechanisms in multi-drug resistance associated with vault's proteins and translation initiation ...

    Call: SONATA BIS 8 , Panel: NZ7

    Principal investigator: dr hab. Witold Szaflarski

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

  27. Association of TXNDC5 and calreticulin with decreased ER stress, allowing resistant multiple myeloma cells to by-pass pr...

    Call: PRELUDIUM 15 , Panel: NZ5

    Principal investigator: Tadeusz Franciszek Kubicki

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski

  28. Determination of mechanisms and critical molecular partners controlling the multidrug resistance proteins (P-gp and BCRP...

    Call: OPUS 15 , Panel: NZ3

    Principal investigator: dr hab. Marlena Godlewska

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO, Studium Kliniczno-Dydaktyczne

  29. Genomic insights into the mechanisms of drug resistance, virulence and transmission of Mycobacterium tuberculosis strain...

    Call: DAINA 1 , Panel: NZ6

    Principal investigator: dr Tomasz Jagielski

    Uniwersytet Warszawski, Wydział Biologii

  30. Regulation of epithelial to mesenchymal transition and therapy resistance to antitumor therapies by MCPIP1

    Call: SONATA BIS 7 , Panel: NZ5

    Principal investigator: dr hab. Katarzyna Miękus

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  31. Mechanisms underlying insulin resistance in patients with pulmonary arterial hypertension. The role of peroxisome prolif...

    Call: SONATA BIS 7 , Panel: NZ5

    Principal investigator: dr hab. Grzegorz Kopeć

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum

  32. Study on the use of primary cultures and established cell lines of canine lymphoma in the diagnosis and treatment of lym...

    Call: PRELUDIUM 1 , Panel: NZ5

    Principal investigator: Aleksandra Pawlak

    Uniwersytet Przyrodniczy we Wrocławiu

  33. Proteomic analysis of myeloma plasma cells to determine proteins and pathways involved in acquired resistance to proteas...

    Call: OPUS 13 , Panel: NZ5

    Principal investigator: dr Dominik Dytfeld

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

  34. Evaluation of anticancer properties and molecular mechanisms of action of new hybrid molecules containing uracil skeleto...

    Call: PRELUDIUM 13 , Panel: NZ3

    Principal investigator: dr Angelika Agata Długosz-Pokorska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  35. Pharmacological and optogenetic investigation of the mechanism of action of Deep Brain Stimulation of the ventromedial p...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii PAN

  36. Zinc Deficiency: An essential Variable for the Induction od Resistance to Antidepressants

    Call: PRELUDIUM 13 , Panel: NZ5

    Principal investigator: dr Anna Maria Rafało-Ulińska

    Instytut Farmakologii PAN

  37. Effectiveness of the mechanism regulating the aluminium resistance of wheat under soil drought stress.

    Call: PRELUDIUM 13 , Panel: NZ9

    Principal investigator: Joanna Siecińska

    Instytut Agrofizyki im. Bohdana Dobrzańskiego PAN

  38. Mechanisms mediating the induction of Growth hormone resistance in response to immune stress.

    Call: PRELUDIUM 13 , Panel: NZ9

    Principal investigator: Maciej Wójcik

    Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego PAN

  39. CBR1-dependent metabolism and ABCB1-dependent effux of doxorubicin - search for a novel mechanism of reversing resistanc...

    Call: PRELUDIUM 13 , Panel: NZ7

    Principal investigator: Kamil Tomasz Piska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  40. Evaluation of primary and secondary molecular disorders determinig drug resistance from a group of proteasome inhibitors...

    Call: OPUS 12 , Panel: NZ5

    Principal investigator: prof. Tadeusz Jerzy Robak

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  41. Identification and targeting molecular drug resistance mechanisms in adult B-cell acute lymphoblastic leukemia

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  42. Identification of epigenetic mechanisms contributing to glioma drug resistance

    Call: POLONEZ 3 , Panel: NZ2

    Principal investigator: dr Jakub Karol Mieczkowski

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  43. Role of mitophagy and assessement of bioenergetic status in podocytes in the development of insulin resistance and impai...

    Call: SONATA 12 , Panel: NZ5

    Principal investigator: dr Irena Audzeyenka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  44. The role of cGMP-dependent signaling in the regulation of expression and activity of deacetylase SIRT1: a novel mechanis...

    Call: OPUS 12 , Panel: NZ4

    Principal investigator: dr Dorota Rogacka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  45. Role of Prolactin-Induced Protein (PIP) in breast cancer progression using an adjuvant therapy.

    Call: OPUS 12 , Panel: NZ5

    Principal investigator: prof. Piotr Zbigniew Dzięgiel

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Lekarski

  46. The role of cancer stem cells in extracellular matrix production and drug resistance in ovarian cancer

    Call: SONATA BIS 6 , Panel: NZ5

    Principal investigator: dr hab. Radosław Januchowski

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

  47. Genetic features of Reed-Sternberg cells and their interplay with macrophages in classical Hodgkin lymphoma: identificat...

    Call: HARMONIA 8 , Panel: NZ5

    Principal investigator: prof. Krzysztof Zbigniew Warzocha

    Instytut Hematologii i Transfuzjologii

  48. The role of the transcription factors and the nuclear import receptors regulating the proces of myogenesis in the pathog...

    Call: OPUS 11 , Panel: NZ5

    Principal investigator: dr hab. Monika Karczewska-Kupczewska

    Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

  49. Mechanism of diffusion layers formation in multilayered clads based on light metals of increased impact resistance

    Call: OPUS 11 , Panel: ST8

    Principal investigator: prof. Henryk Zdzisław Paul

    Instytut Metalurgii i Inżynierii Materiałowej im. Aleksandra Krupkowskiego PAN

  50. Old drugs - new perspectives: modulation of antibiotics activity by caffeine and pentoxifylline

    Call: SONATA 11 , Panel: NZ7

    Principal investigator: dr Anna Woziwodzka

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego