Projects funded by the NCN

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231 projects found matching your search criteria :

  1. Ability of CRISPR/dCas9 system and cell-penetrating proteins as the aim of prevention against coronary artery restenosis...

    Call: SONATA 9 , Panel: NZ7

    Principal investigator: dr Maciej Gagat

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Lekarski

  2. Modelling signal peptides based on hidden semi-Markov models for various taxonomic groups of organisms and peptide types

    Call: PRELUDIUM 9 , Panel: NZ2

    Principal investigator: Michał Burdukiewicz

    Uniwersytet Wrocławski, Wydział Biotechnologii

  3. Multifunctional inhibitors of beta-secretase with anti-aggregating properties of neurotoxic peptides - beta-amyloid and ...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Barbara Malawska

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  4. Foldameric miniproteins - structure and catalytic function

    Call: OPUS 11 , Panel: ST5

    Principal investigator: dr hab. Łukasz Berlicki

    Politechnika Wrocławska

  5. The research on the use of novel analogues of endogenous antimicrobial peptides in therapy of staphylococcal skin infect...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  6. Dissecting cancer activome to develop new generation of antibody-drug conjugates

    Call: OPUS 20 (LAP) , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  7. Blocking HVEM/LIGHT interactions using peptides - an innovative approach to immunosuppression

    Call: PRELUDIUM BIS 2 , Panel: ST4

    Principal investigator: dr hab. Adam Kazimierz Sieradzan

    Uniwersytet Gdański, Wydział Chemii

  8. Design of metal-peptide complexes based on amyloid β sequence with a His-2 binding motif as selective receptors in elect...

    Call: PRELUDIUM 20 , Panel: ST4

    Principal investigator: Aleksandra Magdalena Tobolska

    Politechnika Warszawska

  9. Identification of low molecular weight compounds and peptides with high biological activity present in maggot secretions...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Joanna Papaj

    Politechnika Śląska, Centrum Biotechnologii

  10. Multi-scale method for amyloid fibril assembly using protofilament structures predicted by coarse-grained docking simula...

    Call: OPUS 22 , Panel: NZ2

    Principal investigator: dr Michał Koliński

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  11. De novo design of cavity-incorporating mini-proteins and their application in catalysis

    Call: OPUS 22 , Panel: ST4

    Principal investigator: prof. Łukasz Berlicki

    Politechnika Wrocławska

  12. Biological membranes and macromolecular crowding in the function of the hepatitis C virus proteases

    Call: PRELUDIUM BIS 4 , Panel: NZ1

    Principal investigator: prof. Joanna Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  13. Conjugates of peptide nucleic acids with aminoglycosides and fluoroquinolones as a novel strategy to target multi-drug r...

    Call: PRELUDIUM 22 , Panel: ST5

    Principal investigator: Izabela Siekierska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  14. Peptide-based luminescent coordination capsules and cages – towards bio-inspired cavities illuminated by chiral light

    Call: OPUS 25 , Panel: ST5

    Principal investigator: prof. Agnieszka Szumna

    Instytut Chemii Organicznej Polskiej Akademii Nauk

  15. Studies on the metal ions impact on the structure and functions of peptidic inhibitors of aggregation of proteins involv...

    Call: OPUS 1 , Panel: ST5

    Principal investigator: dr Marek Łuczkowski

    Uniwersytet Wrocławski, Wydział Chemii

  16. Novel angiotensin peptides - formation and role in adipose tissue in rat model of obesity and insulin resistance

    Call: HARMONIA 1 , Panel: NZ4

    Principal investigator: prof. Rafał Olszanecki

    Uniwersytet Jagielloński- Collegium Medicum, Wydział Lekarski

  17. Inhibitors, protein aggregation and carbon nanotube

    Call: OPUS 1 , Panel: NZ1

    Principal investigator: dr hab. Mai Li

    INSTYTUT FIZYKI PAN

  18. Human annexin A1 and A2, and their phosphorylated forms, as a molecular target of metal-dependent hydrolysis of peptide ...

    Call: SONATA 1 , Panel: NZ1

    Principal investigator: dr Tomasz Frączyk

    Instytut Biochemii i Biofizyki PAN

  19. The usage of synthetic peptides mimicking flap region of bacterial ureases for estimation of anti-urease diversity in rh...

    Call: SONATA 2 , Panel: NZ6

    Principal investigator: dr Iwona Konieczna

    Uniwersytet Jana Kochanowskiego w Kielcach, Wydział Matematyczno-Przyrodniczy

  20. The impact of synthetic modifications of the histidine side chain on coordination properties of analogues of the N-termi...

    Call: PRELUDIUM 3 , Panel: ST5

    Principal investigator: dr Izabela Zawisza

    Instytut Biochemii i Biofizyki PAN

  21. Structure and dynamics of protein chain at its folding temparature

    Call: PRELUDIUM 3 , Panel: ST4

    Principal investigator: Anna Hałabis

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  22. Activation of endogenous pronociceptive mechanisms of opioid system as an important factors in the development of neurop...

    Call: MAESTRO 3 , Panel: NZ4

    Principal investigator: prof. Barbara Przewłocka

    Instytut Farmakologii PAN

  23. Neural mechanisms underlying pathology of motivation.

    Call: SONATA BIS 2 , Panel: NZ3

    Principal investigator: dr Jan Rodriguez-Parkitna

    Instytut Farmakologii PAN

  24. Synthesis and biological studies of conjugates formed by peptide dendrimers and natural polyphenols and their analogs

    Call: OPUS 4 , Panel: ST5

    Principal investigator: prof. Zofia Lipkowska

    Instytut Chemii Organicznej PAN

  25. SLPI-dependent cutaneous antimicrobial and antiviral immunity.

    Call: OPUS 13 , Panel: NZ6

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  26. Spectroscopic exploration of conformationally variable metal-bound peptide monolayers: towards novel versatile optical n...

    Call: OPUS 15 , Panel: ST4

    Principal investigator: dr Agata Królikowska

    Uniwersytet Warszawski, Wydział Chemii

  27. New regioselective chemical and biochemical strategies for proteins labeling

    Call: OPUS 17 , Panel: ST4

    Principal investigator: prof. Artur Krężel

    Uniwersytet Wrocławski, Wydział Biotechnologii

  28. Design, chemical synthesis and enzymatic evaluation of peptidic substrates and inhibitors of cathepsin C

    Call: PRELUDIUM 4 , Panel: ST5

    Principal investigator: dr Monika Łęgowska

    Uniwersytet Gdański, Wydział Chemii

  29. Synthesis and pharmacological characterization of novel cyclic opioid peptide analogs incorporating fluoro amino acids.

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: dr Justyna Piekielna-Ciesielska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  30. The key mechanizm for the development of allergy to nickel: A role of the filaggrin fragments, a potential carrier prote...

    Call: PRELUDIUM 5 , Panel: NZ6

    Principal investigator: Ewa Podobas

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  31. Exploring the possibility of quantitative analysis of skeletal muscle proteins after thermal treatment based on selected...

    Call: SONATA 6 , Panel: NZ9

    Principal investigator: dr Magdalena Montowska

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Nauk o Żywności i Żywieniu

  32. Application of macrocycles formed by substituted trithiocyanuric acid as template for self-assembly of peptide chains

    Call: PRELUDIUM 6 , Panel: ST5

    Principal investigator: dr Marta Cal

    Uniwersytet Wrocławski, Wydział Chemii

  33. Synthesis and tandem mass spectrometry examination of new ionization tags based on thiazolidinecarboxylic acid and oxazo...

    Call: PRELUDIUM 8 , Panel: ST5

    Principal investigator: Bartosz Setner

    Uniwersytet Wrocławski, Wydział Chemii

  34. In solution or in the membrane? Determination of partition of beta-amyloid peptides between the water and phospholipid p...

    Call: OPUS 19 , Panel: ST4

    Principal investigator: prof. Wojciech Bal

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  35. The use of proteolytic enzymes isolated form nonconventional sources for obtaining biologically active peptides from mil...

    Call: OPUS 1 , Panel: NZ9

    Principal investigator: dr Anna Dąbrowska

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Nauk o Żywności

  36. Studies over the dissociation of peptides in non-aqueous enviroments and the development of a universal counter-ion exch...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr hab. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  37. Synthesis of deltorphin I and dermorphin analogues modified with alfa-alkyl-beta-azido(amino)alanine in postion 2 or 3.

    Call: PRELUDIUM 2 , Panel: ST5

    Principal investigator: Anika Lasota

    POLITECHNIKA ŁÓDZKA, Politechnika Łódzka, Wydział Chemiczny,

  38. Structure and properties of multicomponent lipid films and their interactions with pore-forming peptides.

    Call: OPUS 3 , Panel: ST4

    Principal investigator: dr hab. Sławomir Sęk

    Uniwersytet Warszawski, Wydział Chemii

  39. Interactions of peptide nucleic acids with biologically relevant RNA motifs

    Call: OPUS 3 , Panel: NZ1

    Principal investigator: dr hab. Joanna Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  40. Significance of peptides citrullinated by peptidylarginine deiminase from Porphyromonas gingivalis in periodontitis.

    Call: OPUS 4 , Panel: NZ6

    Principal investigator: dr Katarzyna Gawron

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  41. Lipophilic Prodrug Charge Masking (LPCM) as a novel strategy to enhance oral bioavailability of charged active peptides....

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Agata Elżbieta Gitlin-Domagalska

    Uniwersytet Gdański, Wydział Chemii

  42. Synthetic self-assembled models of transmembrane proteins

    Call: PRELUDIUM 18 , Panel: ST4

    Principal investigator: Grzegorz Dawid Wołczański

    Uniwersytet Wrocławski, Wydział Chemii

  43. Model for antimicrobial peptide-dependent evolution of plastids

    Call: PRELUDIUM 18 , Panel: NZ8

    Principal investigator: Filip Pietluch

    Uniwersytet Wrocławski, Wydział Biotechnologii

  44. Insulin – metallacarborane conjugates: A new strategy to enhance the biological efficacy of peptide drugs

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Marek Goszczyński

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  45. Structural studies of the influence of selected surfactants on the amyloidogenic properties of various forms of beta pep...

    Call: ETIUDA 8 , Panel: ST4

    Principal investigator: Michalina Wilkowska

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

  46. Development of tools for the rational design of peptide therapeutics

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: dr hab. Sebastian Kmiecik

    Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

  47. Characterization of bioactive peptides from chicken feather keratin and products of their transformations occurring duri...

    Call: PRELUDIUM 20 , Panel: NZ9

    Principal investigator: Antoni Taraszkiewicz

    Politechnika Gdańska

  48. Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec...

    Call: OPUS 21 , Panel: NZ1

    Principal investigator: prof. Elżbieta Beata Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  49. Blocking interactions between Rab1b and Rab5 proteins and their negative regulators TBC1D20 and TBC1D17 with synthetic p...

    Call: PRELUDIUM BIS 3 , Panel: NZ1

    Principal investigator: dr hab. Edyta Violetta Gendaszewska-Darmach

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  50. The effect of milk-clotting enzymes from Jiuqu microbes on coagulation and quality developing mechanisms of cheese

    Call: OPUS 22 , Panel: NZ9

    Principal investigator: dr hab. Justyna Żulewska

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauki o Żywności

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