Projects funded by the NCN

Decoding the role and activation signal of SitKR, a novel developmental two-component system, in regulation of gene expr...

Call: PRELUDIUM 24 , Panel: NZ2

Principal investigator: Patrycja Weronika Wadach

Uniwersytet Wrocławski

Evaluation of the role of genes BARS1 and BARS2, which encodes novel oxidosqualene synthase, in the natural diversity of...

Call: OPUS 27 , Panel: NZ2

Principal investigator: dr hab. Agnieszka Jowita Żmieńko

Instytut Chemii Bioorganicznej PAN

Phytotoxicity of plant metabolites of the Carlina genus and their potential use as novel bioherbicides in physiological ...

Call: PRELUDIUM 23 , Panel: NZ9

Principal investigator: Agata Soluch

Instytut Uprawy Nawożenia i Gleboznawstwa - Państwowy Instytut Badawczy

Miniature CRISPR/Cas nucleases for upregulation of utrophin expression: a novel approach for mutation-independent therap...

Call: DAINA 3 , Panel: NZ3

Principal investigator: prof. Józef Dulak

Uniwersytet Jagielloński

Nuclear mRNA retention and delayed translation as a novel mechanism of post-transcriptional mRNA regulation in plants

Call: PRELUDIUM BIS 5 , Panel: NZ3

Principal investigator: dr hab. Dariusz Jan Smoliński

Uniwersytet Mikołaja Kopernika, Wydział Nauk Biologicznych i Weterynaryjnych

Chimeric Rhodopsin as a novel optogenetic tool

Call: SONATINA 7 , Panel: NZ5

Principal investigator: dr Jagoda Płaczkiewicz

Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

Effect of embryonic signals on methylome of the porcine endometrium as a novel mechanism contributing to pregnancy estab...

Call: OPUS 24 , Panel: NZ9

Principal investigator: prof. Agnieszka Wacławik

Instytut Rozrodu Zwierząt i Badań Żywności PAN

Building a genomic atlas of human inner ear malformations: focus on novel genes and functional non-coding regions

Call: OPUS 21 , Panel: NZ5

Principal investigator: prof. Monika Julita Ołdak

Instytut Fizjologii i Patologii Słuchu

Novel mechanism of gene expression control in Eukaryota through regulation of protein-coding transcript polyadenosine ta...

Call: SONATA 16 , Panel: NZ2

Principal investigator: dr Agnieszka Irena Tudek

Instytut Biochemii i Biofizyki PAN

Molecular profiling of novel antipsychotic drug candidates

Call: OPUS 20 , Panel: NZ7

Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

Instytut Farmakologii PAN

Systematic genomic search for novel genes/variants in consanguineous families including males with reproductive failure

Call: OPUS 19 , Panel: NZ5

Principal investigator: prof. Maciej Krzysztof Kurpisz

Instytut Genetyki Człowieka PAN

Identification and analysis of novel pathogenicity markers in uropathogenic Escherichia coli

Call: OPUS 18 , Panel: NZ6

Principal investigator: dr hab. Damian Kamil Gaweł

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Novel insights into hydrogen sulfide-mediated cytoprotection - can H2S prevent the progression of Duchenne muscular dyst...

Call: OPUS 18 , Panel: NZ3

Principal investigator: prof. Agnieszka Łoboda

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The effect of Hmmr gene and its interaction with the endogenous opioid system as a novel mechanism and a therapeutic tar...

Call: SONATA 15 , Panel: NZ5

Principal investigator: dr Dominik Stanisław Skiba

Instytut Genetyki i Hodowli Zwierząt PAN

Effects of a novel nonaddictive opioid on response to stress

Call: PRELUDIUM 17 , Panel: NZ7

Principal investigator: dr Łucja Elżbieta Szumiec

Instytut Farmakologii PAN

Novel FUS-mediated small RNAs derived from snoRNAs: identification, biogenesis and function

Call: SONATA BIS 8 , Panel: NZ2

Principal investigator: dr hab. Katarzyna Dorota Raczyńska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Molecular characterisation of novel mutations in the gene encoding the luteinizing hormone/choriogonadotropin receptor (...

Call: PRELUDIUM 15 , Panel: NZ5

Principal investigator: dr Kamila Julita Adamczuk

Uniwersytet Medyczny w Lublinie

The G231N, E232T, N235D polymorphism in peptidylarginine deiminase gene from P. gingivalis: a novel factor of virulence ...

Call: OPUS 15 , Panel: NZ2

Principal investigator: dr Katarzyna Maria Gawron

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Functional study of a nonsense mutation in the IRF2BPL gene - an attempt to characterise a novel neurodegenerative human...

Call: OPUS 14 , Panel: NZ1

Principal investigator: dr hab. Paweł Lisowski

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Development of the novel experimental gene therapy approach for glaucoma treatment - focusing on the role of RNA-binding...

Call: SONATA 13 , Panel: NZ4

Principal investigator: dr Adrian Smędowski

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

RNA regulatory networks as novel antimicrobial targets in multidrugs resistant bacteria

Call: OPUS 13 , Panel: NZ6

Principal investigator: dr Marek Żywicki

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

The advanced methods of selecting novel AAV capsids and their use in studies of molecular mechanisms of intracellular bl...

Call: OPUS 13 , Panel: NZ1

Principal investigator: dr Leszek Lisowski

Wojskowy Instytut Higieny i Epidemiologii im. gen. Karola Kaczkowskiego

Examining phenotype of mice carrying a novel dominant-negative, spontaneous mutation of spectrin alpha II encoding gene ...

Call: OPUS 13 , Panel: NZ3

Principal investigator: dr hab. Arkadiusz Miążek

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Identification of novel oncogenic/tumor suppressive miRNA-mRNA interactions in pathogenesis of pediatric T-cell acute ly...

Call: PRELUDIUM 13 , Panel: NZ2

Principal investigator: Monika Drobna-Śledzińska

Instytut Genetyki Człowieka PAN

Characterization of a novel intracellular amplifier circuit that controls long-term responsiveness to type I and type II...

Call: OPUS 12 , Panel: NZ2

Principal investigator: prof. Johannes (Hans) Bluijssen (Bluyssen)

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Identification of novel genetics variants as the cause of the premature closure of the cranial sutures in children using...

Call: PRELUDIUM 12 , Panel: NZ5

Principal investigator: Ewelina Maria Bukowska-Olech

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski

An investigation into novel mechanisms of regulation of gene expression in the context of interactions between host and ...

Call: SONATA 11 , Panel: NZ1

Principal investigator: dr Michał Bukowski

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Searching for novel genes essential for human oligo- and azoospermia - mouse 'knockout' model

Call: OPUS 9 , Panel: NZ2

Principal investigator: prof. Maciej Krzysztof Kurpisz

Instytut Genetyki Człowieka PAN

Air Pollution versus Autoimmunity: Role of multiphase aqueous Inorganic Chemistry (APARIC)

Call: SYMFONIA 3 , Panel: ST5

Principal investigator: prof. Rudi van Eldik

Uniwersytet Jagielloński, Wydział Chemii

Three dimensional (3D) visualization of immediate-early genes (IEGs) structure upon activation, using a novel technique:...

Call: PRELUDIUM 8 , Panel: NZ2

Principal investigator: Paweł Maciej Trzaskoma

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Searching for novel mechanisms of gene expression regulation, independent from RNAi pathway - short RNAs derived from sn...

Call: SONATA 7 , Panel: NZ1

Principal investigator: dr Kamilla Bąkowska-Żywicka

Instytut Chemii Bioorganicznej PAN

Neurochemical properties and biological activity of synthetic cathinones (beta-ketoamphetamines) - the psychostimulant "...

Call: OPUS 7 , Panel: NZ7

Principal investigator: prof. Jolanta Barbara Zawilska

Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny

Genome-wide characterization of type I IFN-induced transcriptomes and identification of novel ISGs and their antiviral f...

Call: OPUS 6 , Panel: NZ2

Principal investigator: prof. Johannes Antonius Bluijssen (Bluyssen)

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Combined stem cell-based and gene therapy as a novel strategy to protect photoreceptors - evaluation of renewal mechanis...

Call: OPUS 4 , Panel: NZ5

Principal investigator: prof. Bogusław Bronisław Machaliński

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

Identification of novel genes involved in spermatogenesis and male infertility.

Call: PRELUDIUM 3 , Panel: NZ5

Principal investigator: dr Agnieszka Maria Malcher

Instytut Genetyki Człowieka PAN

An application of novel approaches in the search for linkage of genetic defects and exponents of immune dysregulation re...

Call: OPUS 3 , Panel: NZ5

Principal investigator: dr Izabela Barbara Klich

Uniwersytet Medyczny w Łodzi, I Katedra Pediatrii, Klinika Pediatrii, Onkologii, Hematologii i Diabetologii Uniwersytetu Medycznego w Łodzi

Adenosine 5'-phosphoramidate as a novel signaling molecule; Study of enzymatic synthesis of this nucleotide and analysis...

Call: OPUS 3 , Panel: NZ1

Principal investigator: prof. Andrzej Bolesław Guranowski

Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa i Bioinżynierii

Search for novel genes involved in pathogenesis of combied pituitary hormone deficiency

Call: HARMONIA 2 , Panel: NZ5

Principal investigator: dr Bartłomiej Marcin Budny

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

Novel epigenetic mechanisms involved in Bdnf gene expression in the rat brain

Call: PRELUDIUM 2 , Panel: NZ3

Principal investigator: Agnieszka Walczak

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Identifying of novel virus-encoded GW proteins that inhibit plant and animal RNAi-based defense systems.

Call: PRELUDIUM 2 , Panel: NZ2

Principal investigator: Andrzej Zieleziński

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

CacyBP/SIP as a novel phosphatase in signaling pathways related to cell proliferation and differentiation

Call: OPUS 2 , Panel: NZ1

Principal investigator: prof. Anna Filipek

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Searching for novel genetic and epigenetic factors predisposing to osteoarthritis

Call: OPUS 2 , Panel: NZ2

Principal investigator: dr hab. Malwina Czarny-Ratajczak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

Wall associated kinases in wheat and barley - the novel group of genes involved in resistance against pathogens

Call: OPUS 1 , Panel: NZ9

Principal investigator: prof. Wacław Marian Orczyk

Instytut Hodowli i Aklimatyzacji Roślin - Państwowy Instytut Badawczy

Novel star polymers as nucleic acids delivery agents

Call: OPUS 1 , Panel: ST5

Principal investigator: dr hab. Agnieszka Kowalczuk

Centrum Materiałów Polimerowych i Węglowych PAN

Investigation of novel SYD gene functions in Arabidopsis development, stress responses and hormonal signalling using adv...

Call: PRELUDIUM 1 , Panel: NZ1

Principal investigator: Ernest Bucior

Uniwersytet Warszawski, Wydział Biologii