Novel mechanism of gene expression control in Eukaryota through regulation of protein-coding transcript polyadenosine tail length
2020/39/D/NZ2/02174
Keywords
Descriptors
- NZ2_002: Genomika, transkryptomika i epigenomika
- NZ2_007: Bioinformatyka
Panel
NZ2 – Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology
Host institution
Instytut Biochemii i Biofizyki PAN
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 4
Call
SONATA 16 – announced on 2020-09-15
- Amount awarded
- 1 642 400 PLN
- Project start date
- 2021-10-01
- Project end date
- 2026-09-30
- Project duration
- 60 months (the same as in the proposal)
- Project status
- Pending project
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (2)
-
Modeling of mRNA deadenylation rates reveal a complex relationship between mRNA deadenylation and decay
- Authors:
- Agnieszka Czarnocka-Cieciura, Jarosław Poznański, Matti Turtola, Rafał Tomecki, Paweł S Krawczyk, Seweryn Mroczek, Wiktoria Orzeł, Upasana Saha, Torben Heick Jensen, Andrzej Dziembowski, Agnieszka Tudek
- Academic press:
- EMBO Journal (year: 2024, volume: 43, pages: 6525-6554), Publisher: Springer Nature
- Status:
- Published
- DOI:
- 10.1038/s44318-024-00258-3 – link to the publication
-
A cap 0-dependent mRNA capture method to analyze the yeast transcriptome.
- Authors:
- Nowacka M, Latoch P, Izert MA, Karolak NK, Tomecki R, Koper M, Tudek A, Starosta AL, Górna MW.
- Academic press:
- Nucleic Acids Research (year: 2022, volume: 2,09861111111111, pages: e132), Publisher: Oxford Academic
- Status:
- Published
- DOI:
- 10.1093/nar/gkac903 – link to the publication
Book publications / chapters in book publications (2)
-
Transcriptome-Wide Analysis of mRNA Adenylation Status in Yeast Using Nanopore Sequencing
- Authors:
- Paweł Krawczyk, Agnieszka Tudek, Seweryn Mroczek, Andrzej Dziembowski
- Book:
- Methods in Molecular Biology (year: 2023, volume: 2723, pages: 193-214), Publisher: Springer (Humana Press)
- Status:
- Published
- DOI:
- 10.1007/978-1-0716-3481-3_12 – link to the publication
-
Purification of Enzymatically Active Xrn1 for Removal of Non-capped mRNAs from In Vitro Transcription Reactions and Evaluation of mRNA Decapping Status In Vivo
- Authors:
- Karolina Drążkowska, Rafał Tomecki, Agnieszka Tudek
- Book:
- mRNA Decay (year: 2024, volume: 2863, pages: 81-105), Publisher: Springer Nature
- Status:
- Published