Projects funded by the NCN


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47 projects found matching your search criteria :

  1. Clinical Variants of Hsp70 Chaperone HSPA1L in Protein Folding and Regulation of Glucocorticoid Receptor

    Call: SONATA 20 , Panel: NZ5

    Principal investigator: dr Agnieszka Antonina Kłosowska

    Uniwersytet Gdański

  2. Functional studies of TPM2 gene mutation responsible for the hereditary form of clubfoot disease

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Akshaya Ramanujam

    Uniwersytet Medyczny w Lublinie

  3. Miniature CRISPR/Cas nucleases for upregulation of utrophin expression: a novel approach for mutation-independent therap...

    Call: DAINA 3 , Panel: NZ3

    Principal investigator: prof. Józef Dulak

    Uniwersytet Jagielloński

  4. Structure of algebras associated to triangulations of compact surfaces

    Call: SONATA 19 , Panel: ST1

    Principal investigator: dr Adam Skowyrski

    Uniwersytet Mikołaja Kopernika, Wydział Matematyki i Informatyki

  5. Exploring the influence of genomic features on mutational signatures across tumors

    Call: OPUS 26 , Panel: NZ2

    Principal investigator: dr Damian Michał Wójtowicz

    Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

  6. The role of DNA methylation and alternative splicing involvement in pathogenesisof the spinocerebellar ataxia type 8 (SC...

    Call: OPUS 25 , Panel: NZ4

    Principal investigator: dr hab. Anna Marzena Sułek

    Uczelnia Łazarskiego

  7. Mechanisms and consequences of CD19 loss in B-acute lymphoblastic leukaemia patients relapsing after CD19-CAR-T cell the...

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  8. Transition from genetic to phenotypic antibiotic resistance in de novo bacterial mutants

    Call: OPUS 22 , Panel: NZ1

    Principal investigator: dr Bartłomiej Michał Wacław

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  9. Building a genomic atlas of human inner ear malformations: focus on novel genes and functional non-coding regions

    Call: OPUS 21 , Panel: NZ5

    Principal investigator: prof. Monika Julita Ołdak

    Instytut Fizjologii i Patologii Słuchu

  10. Mutation rate in spruce bark beetle

    Call: PRELUDIUM 20 , Panel: NZ8

    Principal investigator: Anastasiia Mykhailenko

    Uniwersytet Jagielloński, Wydział Biologii

  11. Mutations of cis-regulatory elements as potential mechanism leading to chromatin inaccessibility and gene silencing in c...

    Call: PRELUDIUM 19 , Panel: NZ2

    Principal investigator: Adam Ustaszewski

    Instytut Genetyki Człowieka PAN

  12. Metabolism of very long chain fatty acids and pathophysiological role of fatty acid elongase -1 (ELOVL1)

    Call: OPUS 19 , Panel: NZ4

    Principal investigator: dr hab. Adriana Maria Mika

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  13. Molecular characterization of response to neoadjuvant chemoradiation in patients with locally advanced soft tissue sarco...

    Call: PRELUDIUM BIS 1 , Panel: NZ2

    Principal investigator: prof. Anna Małgorzata Czarnecka

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  14. Development of a new method for gene mutation identification using surface-enhanced Raman spectroscopy

    Call: OPUS 18 , Panel: ST4

    Principal investigator: dr hab. Andrzej Kudelski

    Uniwersytet Warszawski, Wydział Chemii

  15. Role of TP53 mutations in corticotroph pituitary tumors

    Call: PRELUDIUM 18 , Panel: NZ5

    Principal investigator: Monika Pękul

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  16. Analysis of Escherichia coli ydiU mutation suppressors and detergent resistant membrane fraction as a way to discover fu...

    Call: PRELUDIUM 18 , Panel: NZ1

    Principal investigator: Monika Karasiewicz-Urbańska

    Instytut Biochemii i Biofizyki PAN

  17. Development of immunological-molecular system of chondrosarcoma profiling

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: prof. Piotr Łukasz Rutkowski

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  18. Definition of targetable signaling pathways in chronic lymphocytic leukemia patients with rationale to novel therapy wit...

    Call: PRELUDIUM 16 , Panel: NZ5

    Principal investigator: Joanna Knap

    Uniwersytet Medyczny w Lublinie, II Wydział Lekarski z Oddziałem Anglojęzycznym

  19. Systems approach to cancer progression and prognosis: New models and statistics for analysis of genomic data

    Call: OPUS 15 , Panel: ST7

    Principal investigator: prof. Marek Kimmel

    Politechnika Śląska, Wydział Automatyki, Elektroniki i Informatyki

  20. Analysis of let-7 family miRNA expression in the context of BRAF mutation and potencial use of cf-DNA and miRNA in liqui...

    Call: PRELUDIUM 15 , Panel: NZ2

    Principal investigator: Ewelina Perdas

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  21. Functional study of a nonsense mutation in the IRF2BPL gene - an attempt to characterise a novel neurodegenerative human...

    Call: OPUS 14 , Panel: NZ1

    Principal investigator: dr hab. Paweł Lisowski

    Warszawski Uniwersytet Medyczny, I Wydział Lekarski

  22. Study of transcriptional networks disruption on the development of liver cancer: functional analysis of the HNF4A gene m...

    Call: OPUS 13 , Panel: NZ5

    Principal investigator: dr Hiroaki Taniguchi

    Instytut Genetyki i Hodowli Zwierząt PAN

  23. Examining phenotype of mice carrying a novel dominant-negative, spontaneous mutation of spectrin alpha II encoding gene ...

    Call: OPUS 13 , Panel: NZ3

    Principal investigator: dr hab. Arkadiusz Miążek

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  24. Genome-wide mutation screen of the regulome in laryngeal squamous cell carcinoma

    Call: OPUS 12 , Panel: NZ2

    Principal investigator: prof. Maciej Witold Giefing

    Instytut Genetyki Człowieka PAN

  25. Influence of (5'R) and (5'S) 5',8-cyclo-2'-deoxypurines on clustered DNA lesions repair

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Bolesław Tomasz Karwowski

    Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny

  26. The mechanism of regioselective oxidative dehydrogenation of 3-ketosteroids catalyzed by D1-cholest-4-en-3-one dehydroge...

    Call: OPUS 11 , Panel: ST4

    Principal investigator: prof. Maciej Szaleniec

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  27. Assessment of the mechanism of R132H mutation of isocitrate dehydrogenase 1 gene (IDH1R132H) on differentiation and surv...

    Call: PRELUDIUM 11 , Panel: NZ3

    Principal investigator: dr Kamila Anna Rosiak-Stec

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski; Oddział Nauk Biomedycznych

  28. Long non-coding RNAs (lncRNA) as treatment efficacy markers in patients with advanced melanoma harboring BRAF mutation.

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: dr hab. Jacek Mackiewicz

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Nauk o Zdrowiu

  29. The role of the genetic diversity of 3'-UTR of RNA1 in processes of transmission and replication of tomato torrado virus...

    Call: SONATA 11 , Panel: NZ9

    Principal investigator: dr Marta Budziszewska

    Instytut Ochrony Roślin - Państwowy Instytut Badawczy

  30. Searching for genomic regions responsible for the observed divergence in the outcome of multiple endocrine neoplasia typ...

    Call: PRELUDIUM 9 , Panel: NZ5

    Principal investigator: dr Anna Elżbieta Skalniak

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

  31. Molecular mechanisms linking BRAF mutations and the expression of immunoregulatory molecules, galectin-1 and PD-L1 in me...

    Call: PRELUDIUM 8 , Panel: NZ5

    Principal investigator: Maja Magdalena Wasylecka-Juszczyńska

    Instytut Hematologii i Transfuzjologii

  32. Effect of induced mutations and inbred on behavioural traits in guppy.

    Call: OPUS 8 , Panel: NZ8

    Principal investigator: dr Magdalena Zofia Herdegen-Radwan

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  33. Identification of miRNAs involved in classical Hodgkin lymphoma pathogenesis using combined expression and mutation prof...

    Call: HARMONIA 6 , Panel: NZ2

    Principal investigator: dr hab. Maciej Witold Giefing

    Instytut Genetyki Człowieka PAN

  34. De novo mutations as a tool for finding new loci for cardiological diseases

    Call: PRELUDIUM 6 , Panel: NZ2

    Principal investigator: dr Maria Joanna Franaszczyk

    Instytut Kardiologii im. Prymasa Tysiąclecia Stefana Kardynała Wyszyńskiego

  35. Variability of clinical phenotype of glucose metabolism disorders acoording to type of mutation in the gene encoding glu...

    Call: PRELUDIUM 5 , Panel: NZ4

    Principal investigator: Piotr Rafał Gnyś

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  36. Prediction of controlled ovarian hiperstimulation activity on the basis of GDF-9 mRNA expression in the granulosa cells ...

    Call: PRELUDIUM 4 , Panel: NZ5

    Principal investigator: Katarzyna Ewa Ożegowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

  37. The role of gene duplications in evolutionary process, example from yeast Saccharomyces cerevisiae

    Call: SONATA 4 , Panel: NZ8

    Principal investigator: dr Piotr Śliwa

    Uniwersytet Rzeszowski, Pozawydziałowy Zamiejscowy Instytut Biotechnologii Stosowanej i Nauk Podstawowych

  38. An application of novel approaches in the search for linkage of genetic defects and exponents of immune dysregulation re...

    Call: OPUS 3 , Panel: NZ5

    Principal investigator: dr Izabela Barbara Klich

    Uniwersytet Medyczny w Łodzi, I Katedra Pediatrii, Klinika Pediatrii, Onkologii, Hematologii i Diabetologii Uniwersytetu Medycznego w Łodzi

  39. Attempt to identify a molecular basis (mutation) of a new hereditary hemolytic anemia associated with the lack of MPP1 p...

    Call: OPUS 3 , Panel: NZ5

    Principal investigator: dr Dżamila Marta Bogusławska

    Uniwersytet Zielonogórski, Wydział Nauk Biologicznych

  40. Searching for the background of the canine sex reversal syndrome (78,XX disorder of sexual development)

    Call: OPUS 3 , Panel: NZ9

    Principal investigator: prof. Marek Zbigniew Świtoński

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  41. High-resolution phylogenetic analysis of Y chromosomes in Eurasian populations based on Y-STR loci characterized by dive...

    Call: PRELUDIUM 3 , Panel: NZ8

    Principal investigator: Urszula Agata Rogalla

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Lekarski

  42. New beta-lactoglobulin variants with increased affinity to selected highly toxic drugs

    Call: OPUS 3 , Panel: ST5

    Principal investigator: prof. Krzysztof Lewiński

    Uniwersytet Jagielloński, Wydział Chemii

  43. The role of mitochondrial DNA and epigenetic factors in the pathogenesis of Huntington's disease

    Call: OPUS 2 , Panel: NZ2

    Principal investigator: prof. Janusz Limon

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  44. Molecular aspects of RAS-related disorders in Polish population

    Call: PRELUDIUM 2 , Panel: NZ2

    Principal investigator: Magdalena Pelc

    INSTYTUT - POMNIK - CENTRUM ZDROWIA DZIECKA

  45. Determining the significance of a new potential miRNA-based marker in biology and earlier detection of the ovarian carci...

    Call: MAESTRO 1 , Panel: NZ2

    Principal investigator: prof. Janusz Limon

    Gdański Uniwersytet Medyczny

  46. Analysis of gene polymorphisms and mutations that play a role in Th17 and Treg cells function in patients with rheumatoi...

    Call: SONATA 1 , Panel: NZ5

    Principal investigator: dr Agnieszka Paradowska-Gorycka

    Instytut Reumatologii im. prof. dr hab. med. Eleonory Reicher

  47. Fitness effects of protein instability in the model eukaryotic cells of Saccharomyces cerevisiae.

    Call: OPUS 1 , Panel: NZ8

    Principal investigator: dr Katarzyna Tomala

    Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi