Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Role of TP53 mutations in corticotroph pituitary tumors

2019/35/N/NZ5/03121

Keywords:

mutation TP53 USP8 USP48 corticotroph pituitary tumor next-generation sequencing sequencing

Descriptors:

  • NZ4_5: Anatomical pathology
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

Monika Pękul 

Number of co-investigators in the project: 3

Call: PRELUDIUM 18 - announced on 2019-09-16

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2020-07-22

Project end date (Y-m-d): 2024-07-21

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. Relevance of mutations in protein deubiquitinases genes and TP53 in corticotroph pituitary tumors
    Authors:
    Monika Pękul, Magdalena Szczepaniak, Paulina Kober, Natalia Rusetska, Beata J. Mossakowska, Szymon Baluszek,, Artur Kowalik, Maria Maksymowicz, Grzegorz Zieliński, Jacek Kunicki, Przemysław Witek, Mateusz Bujko
    Academic press:
    Frontiers in Endocrinology (rok: 2024, tom: 15, strony: 1302667), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fendo.2024.1302667 - link to the publication
  2. The Expression of Cell Cycle-Related Genes in USP8-Mutated Corticotroph Neuroendocrine Pituitary Tumors and Their Possible Role in Cell Cycle-Targeting Treatment.
    Authors:
    Mossakowska BJ, Rusetska N, Konopinski R, Kober P, Maksymowicz M, Pekul M, Zieliński G, Styk A, Kunicki J, Bujko M
    Academic press:
    Cancers (rok: 2022, tom: 14(22), strony: 5594), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers14225594 - link to the publication
  3. The Expression of Cell Cycle-Related Genes in USP8-Mutated Corticotroph Neuroendocrine Pituitary Tumors and Their Possible Role in Cell Cycle-Targeting Treatment.
    Authors:
    Mossakowska BJ, Rusetska N, Konopinski R, Kober P, Maksymowicz M, Pekul M, Zieliński G, Styk A, Kunicki J, Bujko M
    Academic press:
    Cancers (rok: 2022, tom: 14(22), strony: 5594), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers14225594 - link to the publication
  4. Relevance of mutations in protein deubiquitinases genes and TP53 in corticotroph pituitary tumors
    Authors:
    Monika Pękul, Magdalena Szczepaniak, Paulina Kober, Natalia Rusetska, Beata J. Mossakowska, Szymon Baluszek,, Artur Kowalik, Maria Maksymowicz, Grzegorz Zieliński, Jacek Kunicki, Przemysław Witek, Mateusz Bujko
    Academic press:
    Frontiers in Endocrinology (rok: 2024, tom: 15, strony: 1302667), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fendo.2024.1302667 - link to the publication
  5. The Expression of Cell Cycle-Related Genes in USP8-Mutated Corticotroph Neuroendocrine Pituitary Tumors and Their Possible Role in Cell Cycle-Targeting Treatment.
    Authors:
    Mossakowska BJ, Rusetska N, Konopinski R, Kober P, Maksymowicz M, Pekul M, Zieliński G, Styk A, Kunicki J, Bujko M
    Academic press:
    Cancers (rok: 2022, tom: 14(22), strony: 5594), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers14225594 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy