Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Fitness effects of protein instability in the model eukaryotic cells of Saccharomyces cerevisiae.

2011/01/B/NZ8/00042

Keywords:

translation fidelity protein instability mutation fitness environmental stress yeast

Descriptors:

  • NZ8_1: Evolutionary biology
  • NZ8_9: Population genetics
  • NZ8_8: Ecotoxicology

Panel:

NZ8 - Evolutionary and environmental biology: evolution, ecology, population biology, biodiversity, biogeography

Host institution :

Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Katarzyna Tomala 

Number of co-investigators in the project: 4

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 192 800 PLN

Project start date (Y-m-d): 2011-12-09

Project end date (Y-m-d): 2014-12-08

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. autoklaw medyczny (6 500 PLN)
  2. inkubator z chłodzeniem (14 000 PLN)
  3. automatyczna pipeta wielokanałowa wraz ze statywem ładującym (6 710 PLN)
  4. pipety wielokanałowe (2 szt.) (2 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Fitness Costs of Minimal Sequence Alterations Causing Protein Instability and Toxicity
    Authors:
    Katarzyna Tomala, Elzbieta Pogoda, Agata Jakubowska, Ryszard Korona
    Academic press:
    Molecular Biology and Evolution (rok: 2014, tom: 31 (3), strony: 703-707), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/molbev/mst264 - link to the publication
  2. Evaluating the Fitness Cost of Protein Expression in Saccharomyces cerevisiae
    Authors:
    Katarzyna Tomala, Ryszard Korona
    Academic press:
    Genome Biology and Evolution (rok: 2013, tom: 5 (11), strony: 2051-2060), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/gbe/evt154 - link to the publication