Projects funded by the NCN

Mitochondrial nucleoside diphosphate kinase (NDPK) as a regulator of mitochondrial proton leak catalyzed by purine nucle...

Call: SONATA 10 , Panel: NZ3

Principal investigator: dr Andrzej Marek Woyda-Płoszczyca

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Synthesis and evaluation of a novel toolkit for biology and biotechnology based on adenine nucleotides analogs

Call: SONATA BIS 5 , Panel: ST5

Principal investigator: dr hab. Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

Look at the mechanism of ovarian cancer cells response to adenine nucleosides modified with metallacarborane clusters wi...

Call: OPUS 9 , Panel: NZ3

Principal investigator: dr Katarzyna Bednarska

Instytut Biologii Medycznej PAN

Extracellular nucleotide gradients as regulators of glioma cell motility

Call: OPUS 9 , Panel: NZ3

Principal investigator: dr hab. Paweł Pomorski

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

New nucleotide analogs containing triazole within oligophosphate bridge as mimics of the 5' end of mRNA - synthesis, pro...

Call: PRELUDIUM 9 , Panel: ST5

Principal investigator: Sylwia Ciechanowicz

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Functional analysis of SLC35A transporter family - substrate specificity and ability to interact with other proteins in ...

Call: OPUS 8 , Panel: NZ3

Principal investigator: prof. Mariusz Olczak

Uniwersytet Wrocławski, Wydział Biotechnologii

Characteristics of nucleotide sugar transporters SLC35A4 and SLC35A5

Call: PRELUDIUM 8 , Panel: NZ1

Principal investigator: Paulina Jadwiga Sosicka

Uniwersytet Wrocławski, Wydział Biotechnologii

From a molecular in silico model to cellular response in vitro. Modified nucleosides as photo and/or radiosensitizers of...

Call: MAESTRO 6 , Panel: ST4

Principal investigator: prof. Janusz Adam Rak

Uniwersytet Gdański, Wydział Chemii

Studies on the synthesis of newly discovered cyclic N6-threonylcarbamoyladenosine (ct6A) and its analogues and on the in...

Call: PRELUDIUM 7 , Panel: ST5

Principal investigator: Michał Robert Matuszewski

Politechnika Łódzka, Wydział Chemiczny

Metabolic profiles, gene polymorphism in NAT2, GSTM1, GSTP1, CYP1A1, COMT and epidemiological data in a holistic approac...

Call: PRELUDIUM 7 , Panel: NZ7

Principal investigator: Emilia Leila Daghir-Wojtkowiak

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Biosynthesis of seleno-modified nucleosides in the anticodon loop of transfer ribonucleic acids. Evaluation of the enzym...

Call: OPUS 7 , Panel: ST5

Principal investigator: prof. Barbara Czesława Nawrot

Centrum Badań Molekularnych i Makromolekularnych PAN

Methods and algorithms of discovering novel phenomena in genomes and transcriptomes with the statistical analysis of nuc...

Call: PRELUDIUM 7 , Panel: ST6

Principal investigator: Marek Stanisław Wiewiórka

Politechnika Warszawska, Wydział Elektroniki i Technik Informacyjnych

Abnormal metabotropic-nucleotide-receptors (P2Y) - dependent calcium response in myoblasts derived from mouse with mutat...

Call: OPUS 6 , Panel: NZ3

Principal investigator: prof. Krzysztof Olaf Zabłocki

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

New gamma-lactam analogues of homo-N-nucleosides

Call: PRELUDIUM 6 , Panel: NZ7

Principal investigator: Joanna Gotkowska

Uniwersytet Medyczny w Łodzi, Katedra Chemii Bioorganicznej i Biokoordynacyjnej

Synthesis, biological and biophysical evaluation of mRNA cap-peptide conjugates for targeted delivery of cap analogues t...

Call: OPUS 6 , Panel: ST5

Principal investigator: dr hab. Marzena Jankowska-Anyszka

Uniwersytet Warszawski, Wydział Chemii

Thermodynamic insights into design of functionally optimized modified siRNAs and their experimental verification.

Call: SONATA BIS 3 , Panel: NZ1

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej PAN

Isosterically modified acyclic nucleoside phosphonates

Call: OPUS 5 , Panel: NZ7

Principal investigator: prof. Andrzej Edward Wróblewski

Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny

The effect of long-term physical training on changes in the metabolism of nucleotides and their derivatives in blood.

Call: OPUS 5 , Panel: NZ7

Principal investigator: dr hab. Jacek Zieliński

Akademia Wychowania Fizycznego im. Eugeniusza Piaseckiego w Poznaniu, Wydział Wychowania Fizycznego, Sportu i Rehabilitacji

New methods for mRNA 5' end labeling and examples of their application in studies on RNA metabolism and searching for in...

Call: OPUS 5 , Panel: ST5

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Synthesis and study of spectroscopic and bilogical properties of nucleosides modyfied by new stilbene derivatives

Call: OPUS 4 , Panel: ST5

Principal investigator: dr hab. Przemysław Ryszard Szczeciński

Politechnika Warszawska, Wydział Chemiczny

An assessment of the relationship between the risk of stroke and the single nucleotide polymorphizm in the genome - wide...

Call: OPUS 4 , Panel: NZ7

Principal investigator: prof. Krzysztof Ziaja

Śląski Uniwersytet Medyczny

Pronucloetides - a pathway to cellular DNA sensitization to ionizing radiation

Call: PRELUDIUM 4 , Panel: ST5

Principal investigator: Magdalena Danuta Zdrowowicz

Uniwersytet Gdański, Wydział Chemii

Development of chemical method for synthesis of biologically active triphosphates using thermolabile protecting groups

Call: OPUS 4 , Panel: ST5

Principal investigator: dr hab. Marcin Krzysztof Chmielewski

Instytut Chemii Bioorganicznej PAN

The impact of rs868 single nucleotide polymorphism on the outcome of liver transplantation in hepatitis C

Call: PRELUDIUM 3 , Panel: NZ6

Principal investigator: Emir Ahmed Sajjad

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

New 3,8-disubstituted purine nucleoside analogues as prospective application for research of structure and biological ac...

Call: SONATA 3 , Panel: ST5

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej PAN

Influence of nucleotide sequence on the yield of radio- and photodamage to double stranded DNA fragments labelled with t...

Call: OPUS 3 , Panel: ST5

Principal investigator: prof. Janusz Adam Rak

Uniwersytet Gdański, Wydział Chemii

Pirymidine phosphorothioate analogues of nucleotides as multifunctional regulators of P2Y6 and P2Y14 nucleotide receptor...

Call: PRELUDIUM 3 , Panel: NZ5

Principal investigator: Edyta Węgłowska

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

Functional analyses of single nucleotide polymorphisms, rs10814948/9p24.2 and rs6702619/1p21.1, associating with colorec...

Call: PRELUDIUM 3 , Panel: NZ2

Principal investigator: Natalia Maryan

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Adenosine 5'-phosphoramidate as a novel signaling molecule; Study of enzymatic synthesis of this nucleotide and analysis...

Call: OPUS 3 , Panel: NZ1

Principal investigator: prof. Andrzej Bolesław Guranowski

Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa i Bioinżynierii

New reagents and methods in synthesis of modified nucleotides and their application for preparation biochemical tools an...

Call: SONATA BIS 1 , Panel: ST5

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Phylogeography and population genomics of the red fox, Vulpes vulpes

Call: OPUS 3 , Panel: NZ8

Principal investigator: prof. Jan Marek Wójcik

Instytut Biologii Ssaków PAN

Association genetics of nucleotide polymorphisms related to adaptive variation and population history in the European ra...

Call: SONATA BIS 1 , Panel: NZ9

Principal investigator: dr hab. Witold Marcin Wachowiak

Instytut Dendrologii PAN

Genomics of adaptation in oak and beech, as model forest tree species

Call: MAESTRO 2 , Panel: NZ9

Principal investigator: prof. Jarosław Burczyk

Uniwersytet Kazimierza Wielkiego, Wydział Nauk Przyrodniczych

Stereodefined phosphorothioate analogs of DNA with incorporated LNA-type nucleosides - synthesis and properties of compl...

Call: OPUS 2 , Panel: ST5

Principal investigator: dr hab. Piotr Jerzy Guga

Centrum Badań Molekularnych i Makromolekularnych PAN

A new gereration of anticancer pronucleotides

Call: OPUS 1 , Panel: NZ4

Principal investigator: prof. Jacek Antoni Stawiński

Instytut Chemii Bioorganicznej PAN

Varification of hypothesis connected with domestication of dog (Canis familiaris) using SNP genotyping

Call: OPUS 1 , Panel: NZ8

Principal investigator: prof. Wiesław Zbigniew Bogdanowicz

Muzeum i Instytut Zoologii PAN

Effect of single nucleotide polymorphism (SNP) in the human chorionic gonadotropin beta subunit gene on its expression i...

Call: OPUS 1 , Panel: NZ4

Principal investigator: dr Mirosław Andrusiewicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Nauk o Zdrowiu

Genomics of hybridization, adaptive variation and demography in hybrid zones of closely related pine species (genus Pinu...

Call: OPUS 1 , Panel: NZ8

Principal investigator: dr hab. Witold Marcin Wachowiak

Instytut Dendrologii PAN

Chromatographic determination of nucleic acids (DNA, RNA) and their constituents (nucleosides, nucleotides, oligonuceoti...

Call: SONATA 1 , Panel: ST4

Principal investigator: dr Sylwia Studzińska

Uniwersytet Mikołaja Kopernika, Wydział Chemii, Katedra Chemii Środowiska i Bioanalityki

Aryl nucleoside phosphoroamidates - a new generation of anti-HIV pronucleotides.

Call: OPUS 1 , Panel: ST5

Principal investigator: prof. Jacek Antoni Stawiński

Instytut Chemii Bioorganicznej PAN

Chemical syntesis and evaluation of biochemical properties of 7-methyloguanosine 5'-diphosphate analogs as inhibitors of...

Call: PRELUDIUM 1 , Panel: NZ1

Principal investigator: Marcin Jarosław Ziemniak

Uniwersytet Warszawski, Wydział Fizyki

Regulation of Expression of Ecto-5'-Nucleotidase - Changes in Pathology and Therapeutic Potential

Call: OPUS 1 , Panel: NZ4

Principal investigator: dr hab. Ryszard Tomasz Smoleński

Gdański Uniwersytet Medyczny, Wydział Lekarski

Conjugates of cap analogs with nanomaterials and biomolecules with potential applications in pharmacology or diagnostics

Call: SONATA 1 , Panel: ST5

Principal investigator: dr Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki