Search results

101. Activity of the opioid system in the pathogenesis and therapy of inflammatory disorders in mouse lines with high and low…

Principal investigator: dr hab. Jakub Jerzy Fichna

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: OPUS 7, Panel: NZ4

102. Oral endoglin based-DNA vaccine combined with gene encoding IL-12 can polarize tumor microenvironment from proangiogenic…

Principal investigator: dr Magdalena Jarosz-Biej

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Call: OPUS 6, Panel: NZ4

103. Conjugates of prion protein with dendrimers as inhibitors of Abeta peptide amyloidogenesis and cytotoxicity of potential…

Principal investigator: dr hab. Krzysztof Nieznański

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: HARMONIA 5, Panel: NZ4

104. Cell replacement therapy for restoring motor function in paraplegic rats - selective activation of serotonergic neurons …

Principal investigator: prof. Urszula Sławińska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 5, Panel: NZ4

105. Phosphonic inhibitors of human neutrophil elastase in cancer therapy

Principal investigator: dr Łukasz Winiarski

Politechnika Wrocławska, Wydział Chemiczny

Call: SONATA 5, Panel: NZ4

106. Vibrational spectroscopy in analysis of biochemical status of blood that mirrors vascular wall pathology in animals with…

Principal investigator: Emilia Antonina Staniszewska-Ślęzak

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Call: PRELUDIUM 5, Panel: NZ4

107. Potential neuroprotective properties of therapy combining hyperbaric oxygen or hypobaric hypoxia postconditioning with m…

Principal investigator: Marcin Gamdzyk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 4, Panel: NZ4

108. Activation of endogenous pronociceptive mechanisms of opioid system as an important factors in the development of neurop…

Principal investigator: prof. Barbara Elżbieta Przewłocka

Instytut Farmakologii PAN

Call: MAESTRO 3, Panel: NZ4

109. Epicutaneous (EC) application of a protein antigen as a new method to treat collagen induced arthritis (CIA) in humanize…

Principal investigator: prof. Marian Szczepanik

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Nauk o Zdrowiu

Call: OPUS 2, Panel: NZ6

110. Histological and behavioral correlates of abnormal magnetic resonance markers of the brain in rats of high fat diet

Principal investigator: dr hab. Stefan Gaździński

Wojskowy Instytut Medycyny Lotniczej

Call: OPUS 2, Panel: NZ4

111. Opioid receptors in the basal ganglia of the brain as targets for alcohol abuse therapy.

Principal investigator: dr Jan Manuel Rodriguez Parkitna

Instytut Farmakologii PAN

Call: OPUS 2, Panel: NZ4

112. Exploring new drug targets for efficacious therapy of neuropathic pain basing on the assessment and modulation of neuroi…

Principal investigator: dr hab. Joanna Gabriela Mika

Instytut Farmakologii PAN

Call: OPUS 2, Panel: NZ4

113. ErbB2-ErbB3/CD151/laminin binding integrins in breast carcinoma: Implications for tumour prognostication and therapy

Principal investigator: prof. Radzisław Kordek

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: OPUS 1, Panel: NZ4

114. Combined targeted therapy with the use of PPAR receptor ligands or statins and cytostatics aimed at molecular mechanisms…

Principal investigator: dr Wojciech Stanisław Placha

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Call: SONATA 1, Panel: NZ4

115. Regulation of Expression of Ecto-5'-Nucleotidase - Changes in Pathology and Therapeutic Potential

Principal investigator: dr hab. Ryszard Tomasz Smoleński

Gdański Uniwersytet Medyczny, Wydział Lekarski

Call: OPUS 1, Panel: NZ4

116. Effect of dietary modulation of RAGE/AGE axis on prostatic neuroendocrine differentiation and the efficacy of anticancer…

Principal investigator: dr Wawrzyniec Dobrucki

Gdański Uniwersytet Medyczny

Call: OPUS 29, Panel: NZ7

117. Pharmacokinetic and pharmacodynamics modeling of antidepressants in a mechanistic approach for efficient therapy.

Principal investigator: prof. Filip Rybakowski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: OPUS 29, Panel: NZ7

118. Dual-acting 5-HT6/5-HT7 receptor antagonists: exploring beneficial effects for the treatment of neurodegenerative disord…

Principal investigator: Michał Kamiński

Uniwersytet Jagielloński

Call: PRELUDIUM 24, Panel: NZ7

119. Development of novel 1,3-selenazol-2-one derivatives incorporated into self-emulsifying drug delivery systems as a strat…

Principal investigator: dr hab. Robert Czarnomysy

Uniwersytet Medyczny w Białymstoku

Call: OPUS 29, Panel: NZ7

120. The Impact of Endocannabinoid System Modulation and Enriched Environment on the Therapy of Myelination and Memory Disord…

Principal investigator: Justyna Anna Socha

Uniwersytet Medyczny w Lublinie

Call: PRELUDIUM 24, Panel: NZ5

121. The impact of H3 histamine receptor modulation on oligodendrogenesis and neurogenesis: a new strategy for the treatment …

Principal investigator: Maciej Degutis

Instytut Farmakologii PAN

Call: PRELUDIUM 24, Panel: NZ5

122. Immersive virtual reality therapy combined with guided breathing exercises as a supportive intervention for reducing dep…

Principal investigator: Magdalena Anna Nowak

Politechnika Opolska

Call: PRELUDIUM 24, Panel: NZ7

123. Disrupting the Toxic NMDAR/TRPM4 Protein Dialogue as a Novel Neuroprotective Strategy: Development of Small-Molecule Inh…

Principal investigator: Katarzyna Aleksandra Szafrańska

Uniwersytet Jagielloński

Call: PRELUDIUM 24, Panel: NZ7

124. Astrocytic contributions to endogenous neuroprotection: Can astrocytes point the way to neuroprotective treatments?

Principal investigator: dr hab. Małgorzata Beręsewicz-Haller

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 29, Panel: NZ5

125. The role of DNA methylation in therapy that increases CFTR channel activity in cystic fibrosis

Principal investigator: dr Beata Maria Narożna

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: SONATA 20, Panel: NZ5

126. The influence of beta2-receptor N-terminal polymorphismsadrenergic on its functionality, interactions withdrugs and the …

Principal investigator: dr hab. Anita Elżbieta Płazińska

Uniwersytet Medyczny w Lublinie

Call: OPUS 28, Panel: NZ7

127. Prolonged-release of selected antiangiogenic proteins from innovative nanocarrier for use in adjuvant/additive multiple …

Principal investigator: prof. Bogusław Bronisław Machaliński

Pomorski Uniwersytet Medyczny w Szczecinie

Call: OPUS 28, Panel: NZ7

128. Cannabidiol as a Neuroprotective Therapy: Are Brain Regeneration Mechanisms After Perinatal Hypoxia-Ischemia Sex-Depende…

Principal investigator: dr Hanna Kletkiewicz

Uniwersytet Mikołaja Kopernika

Call: SONATA 20, Panel: NZ7

129. Decoding the novel role of the histamine H3 receptor in opioid-induced analgesia and hyperalgesia: studies toward innova…

Principal investigator: dr Katarzyna Popiołek-Barczyk

Instytut Farmakologii PAN

Call: OPUS 28, Panel: NZ7

130. Human exosomes as natural carriers of protein kinase CK2 inhibitors and degraders in targeted anticancer therapy.

Principal investigator: dr hab. Patrycja Joanna Wińska

Politechnika Warszawska

Call: OPUS 28 (LAP), Panel: NZ5

131. Biomimetic scaffolds modified with ferulic acid dedicated to necrotic wound therapy

Principal investigator: dr Beata Kaczmarek-Szczepańska

Uniwersytet Mikołaja Kopernika

Call: SONATA 20, Panel: NZ7

132. "Integrated Fixed-Dose Combination Drugs in Depression Therapy: A New Standard of Treatment and Mechanism of Action Stud…

Principal investigator: prof. Gabriel Piotr Nowak

Instytut Farmakologii PAN

Call: OPUS 28, Panel: NZ7

133. FA-PROTACs - Design and Synthesis of Compounds Based on Folic Acid for Degradation of Enzyme Involved in Folate Metaboli…

Principal investigator: dr Mateusz Daśko

Politechnika Gdańska

Call: SONATA 20, Panel: NZ5

134. The first antibody-drug conjugates for Alzheimer's disease therapy

Principal investigator: dr hab. Marcin Łukasz Poręba

Politechnika Wrocławska

Call: SONATA BIS 14, Panel: NZ5

135. M6A RNA methylation signatures as a targets for HPV-dependent HNSCC therapy

Principal investigator: Kamila Ostrowska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: OPUS 27, Panel: NZ5

136. Decoding novel O/K loci of Klebsiella pneumoniae into chemical O/K antigen structures – towards better adjustment of bac…

Principal investigator: prof. Jolanta Katarzyna Łukasiewicz

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: OPUS 27, Panel: NZ7

137. Phage Therapy Antipersister Strategy

Principal investigator: prof. Zuzanna Drulis-Kawa

Uniwersytet Wrocławski

Call: JPIAMR ACTION Call 2024, Panel: NZ6

138. Longitudinal analysis of changes in the expression, activity, and regulation mechanisms of the NLRP3 inflammasome in mon…

Principal investigator: prof. Joanna Saluk

Uniwersytet Łódzki

Call: OPUS 27, Panel: NZ7

139. Assessment of the potential of new histidine hybrids and simulation of their metabolism as a potential therapy for neuro…

Principal investigator: prof. Paweł Bartosz Szymański

Uniwersytet Medyczny w Łodzi

Call: OPUS 27, Panel: NZ7

140. Planetary Health by Healing Forests as Nature Based Solution

Principal investigator: dr Paweł Mateusz Sowa

Uniwersytet Medyczny w Białymstoku

Call: BiodivNBS, Panel: NZ7

141. Comprehensive structural and functional analysis of p53 mRNA to identify secondary and tertiary RNA structures important…

Principal investigator: dr Leszek Michał Błaszczyk

Instytut Chemii Bioorganicznej PAN

Call: OPUS 27, Panel: NZ5

142. Genomic analysis of invasive vancomycin-resistant Enterococcus faecium of VanA phenotype from intensive-care units in Po…

Principal investigator: dr Ewa Nina Wardal

Narodowy Instytut Leków

Call: SONATA 19, Panel: NZ7

143. Potential pharmacological strategies aimed at alleviating cognitive dysfunctions accompanying oncological therapy while …

Principal investigator: dr hab. Joanna Monika Wierońska

Instytut Farmakologii PAN

Call: OPUS 26, Panel: NZ5

144. Semaglutide and neurodevelopment: investigating risks arising from prenatal exposure to a widely popular drug for diabet…

Principal investigator: dr hab. Agnieszka Wnuk

Instytut Farmakologii PAN

Call: OPUS 26, Panel: NZ7

145. CAR(dio)-T(oxicity)- Engineered Heart Tissue model for CAR-T cardiotoxicity evaluation

Principal investigator: dr Agnieszka Joanna Zimna

Instytut Genetyki Człowieka PAN

Call: SONATA 19, Panel: NZ7

146. New biomimetic 3D materials for potential use in advanced therapies of bone tissue diseases - 3D BioBone

Principal investigator: dr hab. Joanna Krystyna Kolmas

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: OPUS 26, Panel: NZ7

147. Modulation of the N-glycosylation as a tool to improve the CAR-T immunotherapy efficacy

Principal investigator: dr Agnieszka Graczyk-Jarzynka

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 26, Panel: NZ7

148. First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect…

Principal investigator: prof. Jadwiga Handzlik

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 26, Panel: NZ7

149. "One step to game changer": combined antimicrobial therapy based on AI and nanotechnology to combat challenging diabetes…

Principal investigator: dr Barbara Ewa Pucelik

Sieć Badawcza ŁUKASIEWICZ - Krakowski Instytut Technologiczny

Call: SONATA 19, Panel: NZ7

150. Bacterial membrane carriers targeting tumor-associated microbes for advanced cancer therapy

Principal investigator: dr Monika Kluzek

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Call: OPUS 26, Panel: NZ7

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