Projects funded by the NCN

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72 projects found matching your search criteria :

  1. Targeted inhibition of STATs and IRFs as a novel treatment strategy in cardiovascular disease

    Call: OPUS 9 , Panel: NZ2

    Principal investigator: prof. Johannes Antonius Bluijssen (Bluyssen)

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  2. DNA repair pathways contributing to resistance to photodynamic therapy and as possible theraupeutic targets

    Call: OPUS 8 , Panel: NZ5

    Principal investigator: dr hab. Elżbieta Speina

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  3. Functional Characterization of Non-Collagenous Extracellular Matrix Proteins as a Potential Molecular Target and Novel B...

    Call: SONATA 8 , Panel: NZ5

    Principal investigator: dr Michał Andrzej Pawlak

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  4. Identification of new, clinically relevant genetic and epigenetic aberrations by next-generation sequencing in chronic m...

    Call: HARMONIA 6 , Panel: NZ5

    Principal investigator: dr Tomasz Artur Stokłosa

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  5. Analysis of relations on the level of metabolome, miRNome, and transcriptome of human renal cancer: towards identificati...

    Call: OPUS 7 , Panel: NZ5

    Principal investigator: dr hab. Agnieszka Piekiełko-Witkowska

    Centrum Medyczne Kształcenia Podyplomowego

  6. Inhibition of p21-Activated Kinase (PAK) as a new molecular target in the treatment of chronic myeloid leukemia (CML)

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: dr hab. Sylwia Flis

    Narodowy Instytut Leków

  7. Disorders of metabolic pathways in breast cancer cells in population of postmenopausal women

    Call: PRELUDIUM 5 , Panel: NZ5

    Principal investigator: Łukasz Kwinta

    Wielkopolskie Centrum Onkologii im. Marii Skłodowskiej-Curie

  8. Targeted genomics of cardiovascular disease - multivariable genetic model of perioperative and long-term cardiovascular ...

    Call: OPUS 5 , Panel: NZ5

    Principal investigator: prof. Marek Jan Sanak

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

  9. Non-targeted metabolite fingerprinting of biological sample using gas chromatography with mass spectrometry detector

    Call: PRELUDIUM 4 , Panel: NZ5

    Principal investigator: Arlette Yumba Mpanga

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  10. Identification of triple negative breast cancer with inactive DNA damage repair pathway by homologous recombination base...

    Call: SONATA 3 , Panel: NZ5

    Principal investigator: dr Paweł Wenancjusz Domagała

    Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

  11. Targeted DNA Capture and Next Generation Sequencing to identify mutations responsible for hearing impairment

    Call: SONATA 2 , Panel: NZ5

    Principal investigator: dr Agnieszka Pollak

    Instytut Fizjologii i Patologii Słuchu

  12. Next-Generation Exosome Therapy: Engineering NK Cell-Derived Vesicles for Targeted Cancer Treatment

    Call: SONATINA 9 , Panel: NZ6

    Principal investigator: dr Daria Nawrocka

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  13. Identifying early biomarkers and molecular targets for therapeutic intervention in right ventricular dysfunction

    Call: OPUS 28 , Panel: NZ5

    Principal investigator: prof. Przemysław Błyszczuk

    Uniwersytet Jagielloński

  14. Selective autophagy-mediated protein degradation as a potential therapeutic strategy for the treatment of inflammatory c...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr hab. Monika Emilia Marcinkowska

    Uniwersytet Jagielloński

  15. M6A RNA methylation signatures as a targets for HPV-dependent HNSCC therapy

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: Kamila Ostrowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  16. Identification of circulating biomarkers for monitoring anti-CD19 CAR-T cell treatment response in patients with aggress...

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Monika Szelest

    Uniwersytet Medyczny w Lublinie

  17. Precision double strike against non-small cell lung cancer. Insights into multidirectional therapies and the landscape o...

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr Katarzyna Anna Malarz

    Politechnika Śląska

  18. Neutrophil-targeted immune response as an effective approach in immunotherapyof gastrointestinal cancers

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr Damian Jacenik

    Uniwersytet Łódzki

  19. Proteomic predictors of metastasis in colorectal cancer – a validation study

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr hab. Anna Wojakowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  20. Modulation of protein interaction networks as a new therapeutic target in the treatment of hereditary retinal dystrophie...

    Call: SONATA 19 , Panel: NZ5

    Principal investigator: dr Xiaonan Liu

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

  21. The inhibition of NMDAR and TRPM4 coupling - a hope for novel therapeutic target for the treatment of the ischemic brain...

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr Bartosz Sebastian Pomierny

    Uniwersytet Jagielloński, Collegium Medicum

  22. Deciphering the Chemoproteomics and Chemotranscriptomics of Anti-Alzheimer Drugs for Novel Druggable Target Identificati...

    Call: WEAVE-UNISONO , Panel: NZ5

    Principal investigator: prof. Krzysztof Sobczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  23. Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Anna Krętowska-Grunwald

    Uniwersytet Medyczny w Białymstoku

  24. Curdlan-based biomaterial as a nanostructure carrier for controlled and targeted drug delivery in the treatment of deep ...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: dr Aleksandra Nurzyńska

    Uniwersytet Medyczny w Lublinie

  25. Cuproptosis, a novel pathway of regulated cell death as a therapeutic target in treatment-naïve and targeted therapy-res...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: dr hab. Mariusz Łukasz Hartman

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  26. Endothelial bioenergetics as a novel target for vascular protection – unveiling the mitochondrial mechanisms of lipid-lo...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: dr Alicja Małgorzata Braczko

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  27. The Role of the Mitochondrial Unfolded Protein Response (UPRmt) in Endothelial Function: a Possible Novel Target for the...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Sylwester Tycjan Mosiołek

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  28. Investigating the role of fibroblast growth factor receptors and STAT transcription factors in the targeted therapy of a...

    Call: PRELUDIUM BIS 4 , Panel: NZ5

    Principal investigator: prof. Ewa Teresa Marcinkowska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  29. Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

    Call: POLONEZ BIS 3 , Panel: NZ5

    Principal investigator: dr Marco Deiana

    Politechnika Wrocławska

  30. Modifiers of Muscleblind-like genes expression in health and disease.

    Call: SONATA BIS 12 , Panel: NZ5

    Principal investigator: dr hab. Ewa Agnieszka Stępniak-Konieczna

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Biotechnologii

  31. Brain cytochrome P450 as a new target for the treatment of neurological and psychiatric diseases. Studies with human neu...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  32. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  33. Targeting of metabolic and transcriptomic cross-talk between leukemic cells and macrophages as a therapeutic strategy in...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Baran Natalia

    Instytut Hematologii i Transfuzjologii

  34. Interleukin-18 receptor targeted gene therapy as a novel approach for the treatment of pulmonary hypertension using cont...

    Call: POLONEZ BIS 1 , Panel: NZ5

    Principal investigator: dr Tara Scott

    Gdański Uniwersytet Medyczny

  35. The role of NPM1 as biomarker of the targeted therapy efficacy in chronic lymphocytic leukemia patients

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Krzysztof Georgios Giannopoulos

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  36. Role of RelA(p65) and cRel phosphorylations and their kinases in the biology of Diffuse-large B-cell lymphoma and Hodgki...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Maciej Stefan Szydłowski

    Instytut Hematologii i Transfuzjologii

  37. In the search of specific oxylipin fingerprint reflecting the development of endothelial dysfunction with the use of non...

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Agnieszka Róża Kij

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  38. New strategies in the treatment of non-small cell lung cancer based on silk nanocarriers targeting tumor vascularization

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Anna Katarzyna Florczak-Substyk

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  39. Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Anna Piotrowska-Murzyn

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  40. ATHENA Study - ArTerial HypErtension PAthogenesis - microRNA as a missing link of the disease development in children.

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: Michał Szyszka

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  41. Functional framework for viral RNA-dependent RNA polymerase, a major target in COVID19 treatment

    Call: Polskie Powroty NAWA 2020 COVID-19 , Panel: NZ1

    Principal investigator: dr Tomasz Wojciech Turowski

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  42. Identification of the interdependence between SWI/SNF-type chromatin remodeling complex, metabolism control and RNA modi...

    Call: OPUS 20 , Panel: NZ5

    Principal investigator: prof. Tomasz Jacek Sarnowski

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  43. The use of surface proteins to capture cancer cells with functionalized magnetic nanoparticles as an innovative theranos...

    Call: OPUS 20 , Panel: NZ5

    Principal investigator: dr hab. Joanna Danuta Dulińska-Litewka

    Uniwersytet Jagielloński, Wydział Chemii

  44. Identification of potential markers aiming early diagnostics of progression and tailoring metastasis-oriented therapies ...

    Call: OPUS 20 , Panel: NZ5

    Principal investigator: dr Natalia Bednarz-Knoll

    Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  45. The significance of circadian rhythm in urinary bladder cancer: deregulation of circadian genes as a putative therapeuti...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: prof. Edyta Wiesława Reszka

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  46. Understanding of the mesenchymal stem cells (MSCs)-mediated immune suppression mechanism in the neutrophilic experimenta...

    Call: PRELUDIUM 19 , Panel: NZ5

    Principal investigator: dr Marlena Tynecka

    Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

  47. Dynamina-2 jako potencjalny cel terapeutyczny w chłoniaku rozlanym z dużych komórek B

    Call: SONATA 15 , Panel: NZ5

    Principal investigator: dr Patryk Górniak

    Instytut Hematologii i Transfuzjologii

  48. New insights into multifaceted targeted therapy for treatment of glioblastoma multiforme.

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr Katarzyna Anna Malarz

    Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

  49. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  50. The 'omics' of renal cancer nucleolus: towards identification of new cancer markers and therapeutic targets.

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: prof. Agnieszka Piekiełko-Witkowska

    Centrum Medyczne Kształcenia Podyplomowego, Szkoła Nauk Medycznych

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