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New insights into multifaceted targeted therapy for treatment of glioblastoma multiforme.

2019/35/B/NZ5/04208

Keywords

Descriptors

  • NZ5_007: Leczenie chorób człowieka
  • NZ7_014: Farmacja, farmakoterapia, farmakologia
  • NZ3_007: Przekaźnictwo sygnału

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

Voivodeship: śląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Katarzyna Anna Malarz

Number of co-investigators in the project: 5

Call

OPUS 18 – announced on 2019-09-16

Amount awarded
1 954 800 PLN
Project start date
2020-07-20
Project end date
2025-11-19
Project duration
64 months (the same as in the proposal)
Project status
Project completed

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (8)

  1. Identification and Biological Evaluation of a Water-Soluble Fullerene Nanomaterial as BTK Kinase Inhibitor

    Authors:
    Malarz K., Korzuch J., Marforio T.D., Balin K., Calvaresi M., Mrozek-Wilczkiewicz A., Musiol R., Serda M.
    Academic press:
    International Journal of Nanomedicine (year: 2023, volume: 18, pages: 16), Publisher: Dove Medical Press
    Status:
    Published
    DOI:
    10.2147/IJN.S403058 – link to the publication

  2. Styrylquinazoline derivatives as ABL inhibitors selective for different DFG orientations

    Authors:
    Katarzyna Malarz, Jacek Mularski, Marcin Pacholczyk, Robert Musiol
    Academic press:
    Journal of Enzyme Inhibition and Medicinal Chemistry (year: 2023, volume: 38, pages: 21), Publisher: Taylor & Francis
    Status:
    Published
    DOI:
    10.1080/14756366.2023.2201410 – link to the publication

  3. Imbalance of redox homeostasis and altered cellular signaling induced by the metal complexes of terpyridine

    Authors:
    Malarz K., Ziola P., Zych D., Rurka P., Mrozek-Wilczkiewicz A.
    Academic press:
    Scientific Reports (year: 2024, volume: 14, pages: 26951), Publisher: Nature Portfolio
    Status:
    Published
    DOI:
    10.1038/s41598-024-77575-4 – link to the publication

  4. 1,8-Naphthalimides 3-substituted with imine or β-ketoenamine unit evaluated as compounds for organic electronics and cell imaging

    Authors:
    M. Korzec, S. Kotowicz, R. Gawecki, K. Malarz, A. Mrozek-Wilczkiewicz, M. Siwy, E. Schab-Balcerzak, J. Grzelak, S. Maćkowski
    Academic press:
    Dyes and Pigments (year: 2021, volume: 193, pages: 9), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.dyepig.2021.109508 – link to the publication

  5. Novel benzenesulfonate scaffolds with a high anticancer activity and G2/M cell cycle arrest

    Authors:
    K. Malarz, J. Mularski, M. Kuczak, A. Mrozek-Wilczkiewicz, R. Musiol
    Academic press:
    Cancers (year: 2021, volume: 8, pages: 24), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13081790 – link to the publication

  6. Spectroscopic and biological properties of the 3-imino-1,8-naphthalimide derivatives as fluorophores for cellular imaging

    Authors:
    Mateusz Korzec, Sonia Kotowicz, Katarzyna Malarz, Anna Mrozek-Wilczkiewicz
    Academic press:
    Molecules (year: 2023, volume: 28, pages: 15), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules28176255 – link to the publication

  7. Anticancer potential and through study of the cytotoxicity mechanism of ionic liquids that are based on the trifluoromethanesulfonate and bis(trifluoromethylsulfonyl)imide anions

    Authors:
    M. Kuczak, M. Musiał, K. Malarz, P. Rurka, E. Zorębski, R. Musioł, M. Dzida, A. Mrozek-Wilczkiewicz
    Academic press:
    Journal of Hazardous Materials (year: 2021, volume: 427, pages: 16), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jhazmat.2021.128160 – link to the publication

  8. Luminescence and Electrochemical Activity of New Unsymmetrical 3-Imino-1,8-naphthalimide Derivatives

    Authors:
    S. Kotowicz, M. Korzec, K. Malarz, A. Krystkowska, A. Mrozek-Wilczkiewicz, S. Golba, M. Siwy, S. Maćkowski, E. Schab-Balcerzak
    Academic press:
    Materials (year: 2021, volume: 14, pages: 23), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14195504 – link to the publication

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