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1. Hsp70 and its cochaperones in protein recovery from aggregates

Principal investigator: prof. Krzysztof Piotr Liberek

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Call: OPUS 18, Panel: NZ1

2. Chaperone machinery in protein refolding from amorphous and fibrillar aggregates

Principal investigator: prof. Krzysztof Piotr Liberek

Uniwersytet Gdański

Call: OPUS 27, Panel: NZ1

3. Impact of OMA1 protease on aggregation-prone proteins associated with neurodegenerative diseases.

Principal investigator: Magda Alicja Krakowczyk

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Call: PRELUDIUM 22, Panel: NZ1

4. Tracing the fibrillation mechanism by nanospectroscopic profiling of structure-dependent tau protein aggregation

Principal investigator: dr Kamila Sofińska

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Call: SONATA 17, Panel: ST4

5. Aggregates of toxic polyglycine protein: in the spotlight. Understanding of formation and degradation processes.

Principal investigator: dr Magdalena Maria Derbis

Instytut Chemii Bioorganicznej PAN

Call: SONATINA 5, Panel: NZ3

6. Studies of the processes of aggregation of GAPDH and other proteins participating in neurodegenerative diseases, induced…

Principal investigator: prof. Grzegorz Bartosz

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska, Katedra Biofizyki Molekularnej

Call: OPUS 3, Panel: NZ1

7. Self-aggregation of protein complexes: virus capsids and amyloids

Principal investigator: dr Panagiotis Theodorakis

Instytut Fizyki PAN

Call: POLONEZ 1, Panel: ST3

8. Inhibitors, protein aggregation and carbon nanotube

Principal investigator: dr hab. Mai Suan Li

Instytut Fizyki PAN

Call: OPUS 1, Panel: NZ1

9. The effect of cytosolic adaptive responses associated with long-term mitochondrial stress on the Tau protein aggregation…

Principal investigator: dr Łukasz Samluk

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: OPUS 17, Panel: NZ3

10. Studies on the metal ions impact on the structure and functions of peptidic inhibitors of aggregation of proteins involv…

Principal investigator: dr Marek Józef Łuczkowski

Uniwersytet Wrocławski, Wydział Chemii

Call: OPUS 1, Panel: ST5

11. Small-molecule inhibitors of protein aggregation and ER stress as a novel strategy against neurodegeneration in the cour…

Principal investigator: prof. Ireneusz Jacek Majsterek

Uniwersytet Medyczny w Łodzi

Call: PRELUDIUM BIS 3, Panel: NZ5

12. Multifunctional inhibitors of beta-secretase with anti-aggregating properties of neurotoxic peptides - beta-amyloid and …

Principal investigator: prof. Barbara Antonina Malawska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 11, Panel: NZ7

13. Role of prion protein in amyloidogenesis and neurotoxicity of Tau protein

Principal investigator: dr hab. Krzysztof Nieznański

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 11, Panel: NZ4

14. Emergence of the two-component small heat shock protein system – a fortified first line of defense against stress in Ent…

Principal investigator: prof. Krzysztof Piotr Liberek

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Call: OPUS 17, Panel: NZ1

15. Clinical Variants of Hsp70 Chaperone HSPA1L in Protein Folding and Regulation of Glucocorticoid Receptor

Principal investigator: dr Agnieszka Antonina Kłosowska

Uniwersytet Gdański

Call: SONATA 20, Panel: NZ5

16. Nuclear protein quality control in neurodegeneration

Principal investigator: dr Lidia Wróbel

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: SONATA 19, Panel: NZ3

17. Molecular mechanisms of chaperones in protein disaggregation

Principal investigator: prof. Krzysztof Piotr Liberek

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Call: MAESTRO 4, Panel: NZ1

18. Protein S-nitrosation as a trigger for DNA leakage from the nucleus: in the quest for a mechanism

Principal investigator: Aleksandra Anna Kopacz

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: PRELUDIUM 18, Panel: NZ3

19. Role of protein acetylation in the formation of antibiotic-tolerant Escherichia coli persisters

Principal investigator: dr hab. Ewa Laskowska

Uniwersytet Gdański, Wydział Biologii

Call: OPUS 2, Panel: NZ1

20. Inhibition of protein disulfide isomerases as a strategy for reduction of prothrombotic state in atherosclerosis; therap…

Principal investigator: dr Kamil Przyborowski

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Call: SONATA 17, Panel: NZ7

21. Prevention of post-translational protein modifications

Principal investigator: prof. Grzegorz Bartosz

Uniwersytet Łódzki, UNIWERSYTET ŁÓDZKI, Katedra Biofizyki Molekularnej

Call: HARMONIA 1, Panel: NZ3

22. Lipid-Proteasome Interplay in Aging and Proteostasis

Principal investigator: Pankaj Thapa

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: SONATINA 9, Panel: NZ1

23. Keap1-dependent proteopathy as a unifying mechanism of vascular dysfunction

Principal investigator: dr hab. Anna Maria Grochot-Przęczek

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 22, Panel: NZ4

24. Toxic RNA with expanded trinucleotide repeats: pathomechanism and therapeutic targets of neurological diseases

Principal investigator: prof. Krzysztof Sobczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: MAESTRO 12, Panel: NZ3

25. Molecular Pathogenesis and Precision Antisense Oligonucleotide Therapy for BAG3-Related Myofibrillar Myopathy Type 6 Usi…

Principal investigator: dr Estera Elmira Rintz

Uniwersytet Gdański

Call: OPUS 29, Panel: NZ2

26. Interactions of amyloid beta peptides with metal ions and lipid membranes: Insights from lattice and all-atom simulation…

Principal investigator: prof. Mai Suan Li

Instytut Fizyki PAN

Call: OPUS 10, Panel: ST4

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