Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Role of protein acetylation in the formation of antibiotic-tolerant Escherichia coli persisters

2011/03/B/NZ1/01206

Keywords:

N-lysine acetylation protein aggregation Escherichia coli acetate stress persisters

Descriptors:

  • NZ1_10: Microbiology
  • NZ1_1: Molecular biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Gdański, Wydział Biologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewa Laskowska 

Number of co-investigators in the project: 5

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 522 000 PLN

Project start date (Y-m-d): 2012-08-22

Project end date (Y-m-d): 2016-02-21

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Inkubator z wytrząsaniem Incu-Shaker Mini, Benchmark (17 000 PLN)
  2. Spektrofotometr UV-VIS (20 000 PLN)
  3. Zasilacz niskonapięciowy (5 000 PLN)
  4. Mikroskop fluoorescencyjny Axio Scope A1 firmy Zeiss, z kamerą i oprogramowaniem (120 000 PLN)
  5. Homogenizator ultradźwiękowy (sonikator), model Omni Ruptor 400.
  6. Inkubator -cieplarka (9 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. The effect of protein acetylation on the formation and processing of inclusion bodies and endogenous protein aggregates in Escherichia coli cells
    Authors:
    Dorota Kuczyńska-Wiśnik, María Moruno-Algara, Karolina Stojowska-Swędrzyńska, Ewa Laskowska
    Academic press:
    Microbial Cell Factories (rok: 2016, tom: 15, strony: 189), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12934-016-0590-8 - link to the publication
  2. Lack of intracellular trehalose affects formation of Escherichia coli persister cells
    Authors:
    Dorota Kuczynska-Wisnik, Karolina Stojowska, Ewelina Matuszewska, Daria Leszczyn ska, Marıa Moruno Algara, Mateusz Augustynowicz, Ewa Laskowska
    Academic press:
    Microbiology (rok: 2015, tom: 161, strony: 000-000), Wydawca: Society for General Microbiology
    Status:
    Published
    DOI:
    10.1099/mic.0.000012 - link to the publication