Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Emergence of the two-component small heat shock protein system – a fortified first line of defense against stress in Enterobacterales

2019/33/B/NZ1/00352

Keywords:

chaperone proteins protein aggregation protein disaggregation and refolding small heat shock proteins ancestral proteins

Descriptors:

  • NZ1_002:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Krzysztof Piotr Liberek 

Number of co-investigators in the project: 7

Call: OPUS 17 - announced on 2019-03-15

Amount awarded: 2 131 200 PLN

Project start date (Y-m-d): 2020-02-06

Project end date (Y-m-d): 2024-02-05

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Evolution towards simplicity in bacterial small heat shock protein system
    Authors:
    Piotr Karaś, Klaudia Kochanowicz, Marcin Pitek, Przemysław Domański, Igor Obuchowski, Bartłomiej Tomiczek, Krzysztof Liberek
    Academic press:
    eLife (rok: 2023, tom: 12, strony: RP89813), Wydawca: eLife Sciences Publications Ltd
    Status:
    Published
    DOI:
    10.7554/eLife.89813 - link to the publication
  2. The Small Ones Matter—sHsps in the Bacterial Chaperone Network
    Authors:
    Igor Obuchowski, Piotr Karas and Krzysztof Liberek
    Academic press:
    Frontiers in Molecular Biosciences (rok: 2021, tom: 8, strony: ), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmolb.2021.666893 - link to the publication
  3. Small but mighty: a functional look at bacterial sHSPs
    Authors:
    Igor Obuchowski & Krzysztof Liberek
    Academic press:
    Cell Stress and Chaperones Journal (rok: 2020, tom: 25, strony: 593-600), Wydawca: Cell Stress and Chaperones
    Status:
    Published
    DOI:
    10.1007/s12192-020-01094-0 - link to the publication
  4. Two Bacterial Small Heat Shock Proteins, IbpA and IbpB, Form a Functional Heterodimer
    Authors:
    Artur Piro´g, Francesca Cantini, Łukasz Nierzwicki, Igor Obuchowski, Bartłomiej Tomiczek, Jacek Czub and Krzysztof Liberek
    Academic press:
    Journal of Molecular Biology (rok: 2021, tom: 433, strony: ), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jmb.2021. - link to the publication