Search results

301. Role of natural products in overcoming drug resistance in Mycobacterium tuberculosis

Principal investigator: dr Elwira Zofia Sieniawska

Uniwersytet Medyczny w Lublinie

Call: OPUS 23, Panel: NZ7

302. Allosteric and allosteric-orthosteric bitopic ligands of histamine receptor H4 as a way to increase selectivity and bias…

Principal investigator: prof. Sławomir Hubert Filipek

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 23, Panel: NZ7

303. Modulation of HIV-1 epitranscriptome: A novel approach to improve "shock & kill" therapy.

Principal investigator: Haider Ali brak danych (PI has only a Name - in accordance with PESEL)

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Call: PRELUDIUM 21, Panel: NZ6

304. Understanding drug/polymer/plasticizer miscibility and its effect on mechanical properties of polymeric filaments for FD…

Principal investigator: Marta Maria Kozakiewicz-Latała

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Call: PRELUDIUM 21, Panel: NZ7

305. New positive allosteric modulators of EAAT2 glutamate transporter as candidates for treatment of neurological and psychi…

Principal investigator: prof. Krzysztof Tomasz Kamiński

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 23, Panel: NZ7

306. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

Principal investigator: Karolina Barbara Przepiórska-Drońska

Instytut Farmakologii PAN

Call: PRELUDIUM 21, Panel: NZ7

307. The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud…

Principal investigator: dr Magdalena Białoń

Instytut Farmakologii PAN

Call: PRELUDIUM 21, Panel: NZ7

308. A comprehensive approach to powders for pharmaceutical 3D printing using Selective Laser Sintering - development of stra…

Principal investigator: dr hab. Piotr Paweł Kulinowski

Uniwersytet Pedagogiczny im. Komisji Edukacji Narodowej w Krakowie

Call: OPUS 23, Panel: NZ7

309. Combination of FAAH inhibition with action via serotonin 5-HT6 receptor as pioneering approach to fight with Alzheimer D…

Principal investigator: Kinga Maria Czarnota-Łydka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 21, Panel: NZ7

310. Effects of activation of cholinergic, noradrenergic, and serotonergic systems on respiratory impairment in Alzheimer's d…

Principal investigator: prof. Katarzyna Kaczyńska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 23, Panel: NZ7

311. Bioconjugates of 103Pd nanostructures for targeted Auger electron therapy.

Principal investigator: dr hab. Agnieszka Majkowska-Pilip

Instytut Chemii i Techniki Jądrowej

Call: OPUS 23, Panel: ST5

312. Can keto diet save the brain? The effect of the ketogenic diet on glial scar formation after traumatic brain injury.

Principal investigator: Zuzanna Maria Rauk

Uniwersytet Jagielloński, Wydział Biologii

Call: PRELUDIUM 21, Panel: NZ4

313. Extracellular vesicles modifications for future drug delivery systems

Principal investigator: prof. Ewa Łucja Stępień

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Call: OPUS 23, Panel: NZ7

314. Modulating effect of elicitors on the biosynthesis of bioactive metabolites in Nigella damascena in vitro cultures - A t…

Principal investigator: dr Magdalena Klimek-Chodacka

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Biotechnologii i Ogrodnictwa

Call: OPUS 23, Panel: NZ7

315. Pharmacogenomics of SGLT2 inhibitors - investigating the role of empagliflozin in epigenetic modification of non-coding …

Principal investigator: Anna Nowak-Szwed

Warszawski Uniwersytet Medyczny

Call: PRELUDIUM 21, Panel: NZ7

316. The application of artificial intelligence to the discovery of new natural drugs with mechanisms aimed at lowering free …

Principal investigator: Maciej Spiegel

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Farmaceutyczny

Call: PRELUDIUM 21, Panel: NZ7

317. EEG/ECoG based functional connectivity neuroimaging in the rat - optimisation, standardisation and translational leap in…

Principal investigator: prof. Daniel Krzysztof Wójcik

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: WEAVE-UNISONO, Panel: NZ4

318. The effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on changes in selected epigenetic mechan…

Principal investigator: Agnieszka Magdalena Woźniak

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: PRELUDIUM 21, Panel: NZ7

319. Amino acids among biomarkers for blood pressure level – causal inference using molecular, epidemiological, and genetic a…

Principal investigator: dr hab. Mateusz Siedliński

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 23, Panel: NZ4

320. Transgenerational inheritance of Liver Disease in mouse offspring conceived by Assisted Reproduction Technologies.

Principal investigator: dr Maria Florencia Heber

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Call: SONATINA 6, Panel: NZ4

321. Enhancement of antidepressant therapy by combined administration of hyperforin and ketamine: behavioral and molecular st…

Principal investigator: dr Bartłomiej Pochwat

Instytut Farmakologii PAN

Call: SONATA 17, Panel: NZ7

322. The use of genetic analysis of liquid biopsy for predicting and monitoring ofresponse to therapies and tumor evolution i…

Principal investigator: dr Magdalena Olbryt

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Call: OPUS 22, Panel: NZ7

323. Characterization of childhood asthma and IgE-dependent allergy asthma endotypes using integrated clinical, metabolomic a…

Principal investigator: prof. Jan Franciszek Matysiak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: PRELUDIUM BIS 3, Panel: NZ5

324. Mechanisms and consequences of small cerebral blod vessels dysfunction inexperimental hyponatremia in the presence of va…

Principal investigator: dr Marta Aleksandrowicz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: SONATA 17, Panel: NZ4

325. Molecular determinants of input specificity in plasticity phenomena at GABAergic synapses in the hippocampus

Principal investigator: prof. Jerzy Władysław Mozrzymas

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Call: OPUS 22, Panel: NZ4

326. Electrospun nanofiber-based nanoplatform for delivery of new nutraceutical derivatives to eliminate chemotherapy-induced…

Principal investigator: dr hab. Maciej Antoni Wnuk

Uniwersytet Rzeszowski, Collegium Medicum

Call: OPUS 22, Panel: NZ7

327. Cognitive impairment in chronic pain - CBD as the undervalued remedy.

Principal investigator: prof. Katarzyna Maria Starowicz-Bubak

Instytut Farmakologii PAN

Call: OPUS 22, Panel: NZ7

328. Targeting UDP-glucose and P2Y14 receptor interaction for therapeutic modulation of inflammatory lung diseases

Principal investigator: dr Tadeusz Piotr Karcz

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA 17, Panel: NZ7

329. Biological roles of transcriptional networks activated in the brain by psychotropic drugs

Principal investigator: dr hab. Michał Korostyński

Instytut Farmakologii PAN

Call: PRELUDIUM BIS 3, Panel: NZ7

330. Perinuclear AKAP6 signalosome as a new target for gene therapy in ischemic optic neuropathy

Principal investigator: dr hab. Tomasz Boczek

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

Call: OPUS 22, Panel: NZ4

331. Involvement of gasotransmitter systems in the brain response to seizure activity in animal models of epilepsy

Principal investigator: prof. Krzysztof Jan Janeczko

Uniwersytet Jagielloński, Wydział Biologii

Call: PRELUDIUM BIS 3, Panel: NZ4

332. Bifunctional, pH-responsive zeolite-bisphosphonates complex as a base for the production of smart bone implant for osteo…

Principal investigator: prof. Agata Natalia Przekora-Kuśmierz

Uniwersytet Medyczny w Lublinie, Wydział Nauk Medycznych

Call: OPUS 22, Panel: NZ7

333. Glymphatic system in epilepsy pathogenesis.

Principal investigator: prof. Katarzyna Łukasiuk

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 22, Panel: NZ4

334. Impact of the CDK4/6 targeted degradation by PROTACs on immune checkpoint signaling in cancer

Principal investigator: dr Katarzyna Magiera-Mularz

Uniwersytet Jagielloński, Wydział Chemii

Call: OPUS 22, Panel: NZ7

335. Novel pathway of vitamin B12 activation by CD73 - analysis of molecular mechanisms, in vivo processing and clinical rele…

Principal investigator: dr hab. Marta Urszula Tomczyk

Gdański Uniwersytet Medyczny, Wydział Lekarski

Call: SONATA 17, Panel: NZ4

336. Translational and interdisciplinary investigation of phenotypes of reinforcement sensitivity as predictors of the respon…

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

Call: OPUS 22, Panel: HS6

337. Bioresorbable, electrospun nonwoven as a multi-drug delivery system for a combination glioblastoma therapy

Principal investigator: dr Monika Anna Musiał-Kulik

Centrum Materiałów Polimerowych i Węglowych PAN

Call: SONATA 17, Panel: NZ7

338. Novel broad-spectrum central nervous system active substances: optimization of their multi-target profile

Principal investigator: dr hab. Agnieszka Anna Kaczor

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Call: OPUS 22, Panel: NZ7

339. Keap1-dependent proteopathy as a unifying mechanism of vascular dysfunction

Principal investigator: dr hab. Anna Maria Grochot-Przęczek

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 22, Panel: NZ4

340. Structure-guided design of histone demethylase inhibitors for cancer therapy.

Principal investigator: dr Piotr Henryk Małecki

Instytut Chemii Bioorganicznej PAN

Call: SONATA 17, Panel: NZ7

341. Development of the knowledge on the role of GPR18 ligands as a microglia-targeted strategy in the regulation of neuroinf…

Principal investigator: dr Ewelina Barbara Honkisz-Orzechowska

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA 17, Panel: NZ3

342. Inhibition of protein disulfide isomerases as a strategy for reduction of prothrombotic state in atherosclerosis; therap…

Principal investigator: dr Kamil Przyborowski

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Call: SONATA 17, Panel: NZ7

343. Multiomic level analyses in atypical diabetes patient derived iPSC and pancreatic cells- key to function

Principal investigator: dr hab. Maciej Maurycy Łałowski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: POLONEZ BIS 1, Panel: NZ4

344. Bleomycin hydrolase, homocysteine metabolism, epigenetic regulation of mTOR signalling, autophagy, and Alzheimer's disea…

Principal investigator: dr hab. Joanna Perła-Kaján

Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Biotechnologii

Call: OPUS 22, Panel: NZ4

345. New strategies in the treatment of non-small cell lung cancer based on silk nanocarriers targeting tumor vascularization

Principal investigator: dr Anna Katarzyna Florczak-Substyk

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: SONATA 17, Panel: NZ7

346. Light-producing, oxygen-delivering, cancer cell-targeted carriers for photosensitisers dedicated for photodynamic therap…

Principal investigator: prof. Marek Arkadiusz Murias

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: OPUS 22, Panel: NZ7

347. Dual 5-HT3 receptor/5-HT6 receptor antagonists in neuropsychiatric and neurological disorders

Principal investigator: prof. Paweł Maria Zajdel

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 22, Panel: NZ7

348. Species belonging to lichens and bryophytes as a useful source of biologically active compounds in therapy of skin disea…

Principal investigator: prof. Sławomir Daniel Dresler

Uniwersytet Medyczny w Lublinie

Call: PRELUDIUM BIS 3, Panel: NZ7

349. A new animal model of human McArdle disease in zebrafish (Danio rerio)

Principal investigator: dr hab. Marta Migocka-Patrzałek

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: SONATA 17, Panel: NZ4

350. The role of the immune checkpoints in the pathomechanism of depressive disorders.

Principal investigator: prof. Marta Wanda Kubera

Instytut Farmakologii PAN

Call: OPUS 22, Panel: NZ6

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