Molecular determinants of input specificity in plasticity phenomena at GABAergic synapses in the hippocampus

2021/43/B/NZ4/01675

Keywords

Descriptors

  • NZ4_007: Neurofizjologia
  • NZ4_009: Neurobiologia systemowa
  • NZ3_006: Neurobiologia komórkowa

Panel

NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Voivodeship: dolnośląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Jerzy Władysław Mozrzymas

Number of co-investigators in the project: 7

Call

OPUS 22 – announced on 2021-09-15

Amount awarded
2 843 400 PLN
Project start date
2022-09-02
Project end date
2027-09-01
Project duration
60 months (the same as in the proposal)
Project status
Pending project

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (6)

  1. NMDA-Dependent Coplasticity in VIP Interneuron-Driven Inhibitory Circuits

    Authors:
    Jadwiga Jabłońska, Grzegorz Wiera, Jerzy W. Mozrzymas
    Academic press:
    Journal if Neurochemistry (year: 2025, volume: Volume169, pages: Volume169, Issue6), Publisher: WILEY
    Status:
    Published
    DOI:
    10.1111/jnc.70117 – link to the publication
  2. Input specificity of NMDA-dependent GABAergic plasticity in the hippocampus

    Authors:
    Grzegorz Wiera, Jadwiga Jabłońska, Anna Maria Lech & Jerzy W. Mozrzymas
    Academic press:
    Scientific Reports (year: 2024, volume: 14, pages: Article number: 20463 (2024)), Publisher: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-024-70278-w – link to the publication
  3. D1-type dopamine receptors are critical for GABAergic synaptic plasticity in CA1 mouse hippocampal SST interneurons and pyramidal cells

    Authors:
    Patrycja Brzdąk , Katarzyna Lebida , Patrycja Droździel , Emilia Stefańczyk , Aleksandra Leszczyńska , Jerzy W. Mozrzymas
    Academic press:
    Progress in Neurobiology (year: 2025, volume: Volume 255, pages: Volume 255, December 2025, 102845), Publisher: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.pneurobio.2025.102845 – link to the publication
  4. GABAergic synapses onto SST and PV interneurons in the CA1 hippocampal region show cell‑specifc and integrin‑dependent plasticit

    Authors:
    J. Mozrzymas, K. Lebida, P. Brzdąk, M. Wyroślak
    Academic press:
    Scientific Reports (year: 2023, volume: 13, pages: 5079), Publisher: Nature Portfolio
    Status:
    Published
    DOI:
    10.1038/s41598-023-31882-4 – link to the publication
  5. Extracellular matrix integrity regulates GABAergic plasticity in the hippocampus

    Authors:
    Jadwiga Jabłońska 1 , Grzegorz Wiera 1 , Jerzy W. Mozrzymas
    Academic press:
    Matrix Biology (year: 2024, volume: Volume 134, pages: 184-196), Publisher: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.matbio.2024.11.001 – link to the publication
  6. Molecular mechanisms of the GABA type A receptor function

    Authors:
    Michał A. Michałowski Open the ORCID record for Michał A. Michałowski, Karol Kłopotowski , Grzegorz Wiera , Marta M. Czyżewska, Jerzy W. Mozrzymas
    Academic press:
    Quarterly Reviews of Biophysics (year: 2025, volume: Volume 58, pages: Volume 58 , 2025 , e3), Publisher: Published online by Cambridge University Press
    Status:
    Published
    DOI:
    10.1017/S0033583524000179 – link to the publication

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