Projects funded by the NCN

Next-Generation Exosome Therapy: Engineering NK Cell-Derived Vesicles for Targeted Cancer Treatment

Call: SONATINA 9 , Panel: NZ6

Principal investigator: dr Daria Nawrocka

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Role of stem cell- derived extracellular vesicles in regulation of autophagy and mitochondrial homeostasis in cardiac ce...

Call: OPUS 28 , Panel: NZ4

Principal investigator: prof. Ewa Katarzyna Zuba-Surma

Uniwersytet Jagielloński

PET micro- and nanoplastics as modulators of intercellular communication in oviductal epithelial cells: The role of extr...

Call: OPUS 28 , Panel: NZ3

Principal investigator: prof. Iwona Urszula Bogacka

Uniwersytet Warmińsko-Mazurski w Olsztynie

Aptamer-mediated SERS/DEP Biosensors for proteomic analysis of extracellular vesicles of salivary gland tumors: towards ...

Call: OPUS 28 , Panel: ST4

Principal investigator: prof. Agnieszka Edyta Michota-Kamińska

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Autophagy in autoimmune vasculitis: a multiomics approach

Call: SONATA BIS 14 , Panel: NZ6

Principal investigator: dr hab. Marcin Piotr Surmiak

Uniwersytet Jagielloński

A new universal method for the isolation and deep proteomic characterization of extracellular vesicles to study drug res...

Call: PRELUDIUM 23 , Panel: NZ2

Principal investigator: Bianka Świderska

Instytut Biochemii i Biofizyki PAN

Do interactions between plants and endophytic bacteria's extracellular vesicles in the presence of heavy metals improve ...

Call: PRELUDIUM 23 , Panel: NZ9

Principal investigator: Iryna Bodnaruk

UNIWERSYTET ŚLĄSKI

Phoenixin as a new factor regulating maternal-embryonic communication in the peri-implantation period - multi-omics appr...

Call: OPUS 27 , Panel: NZ9

Principal investigator: dr hab. Agata Żmijewska

Uniwersytet Warmińsko-Mazurski w Olsztynie

Developmental neurotoxicity of nanoplastic. Functional, structural and molecular analysis of the neurovascular unit in t...

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Kamil Dawid Adamiak

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Analysis of extracellular vesicles isolated from perfusion fluid as potential biomarkers of kidney quality from deceased...

Call: PRELUDIUM 23 , Panel: NZ2

Principal investigator: Maksymilian Baryła

Warszawski Uniwersytet Medyczny

Bacterial outer membrane vesicles and caspase-4-mediated activation of endothelial cells induces secretion of immunomodu...

Call: SONATA 19 , Panel: NZ6

Principal investigator: dr Wojciech Marek Cypryk

Centrum Badań Molekularnych i Makromolekularnych PAN

Evolution and function of astrocytic extracellular vesicles.

Call: SONATA 19 , Panel: NZ3

Principal investigator: dr Katarzyna Ciuba

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

The Impact of Undernutrition on Host Microbiome: the Messenger Role of Bacterial Extracellular Vesicles.

Call: SONATA 19 , Panel: NZ7

Principal investigator: dr Agnieszka Maria Razim

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Extracellular vesicles of probiotic yeast as carriers of biologically active molecules transferred to human intestinal c...

Call: OPUS 25 , Panel: NZ9

Principal investigator: dr hab. Jolanta Mierzejewska

Politechnika Warszawska, Wydział Chemiczny

Towards in-vitro meat: the influence of fibroblast-derived extracellular vesicles in the modulation of bovine satellite ...

Call: PRELUDIUM 22 , Panel: NZ9

Principal investigator: Karolina Małgorzata Zygmunt

Instytut Zootechniki - Państwowy Instytut Badawczy

The anti-inflammatory potential of extracellular vesicles of the parasitic nematode Anisakis simplex in human gastric an...

Call: OPUS 25 , Panel: NZ6

Principal investigator: dr Robert Stryiński

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

Participation of exosomes secreted by neutrophils in the modulation of angiogenesis - the role of the type 1 interferon ...

Call: SONATINA 7 , Panel: NZ5

Principal investigator: dr Mateusz Piotr Smolarz

Akademia Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach

Extracellular vesicles derived from patients with rheumatoid arthritis as modulators of NK cell functionality

Call: OPUS 24 , Panel: NZ3

Principal investigator: prof. Katarzyna Maria Bogunia-Kubik

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

A comparative analysis of the ability to secrete exosomes by different types of human mesenchymal stem/stromal cells (MS...

Call: PRELUDIUM BIS 4 , Panel: NZ3

Principal investigator: dr hab. Anna Otylia Sarnowska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Role of microparticles derived from platelets and cancer cells in colorectal cancer progression – how to stop them or tu...

Call: OPUS 24 , Panel: NZ5

Principal investigator: prof. Maria Anna Kowalska

Instytut Biologii Medycznej PAN

Extracellular vesicles as mediators of intercellular communication in an organism exposed to PET microplastics - multi-o...

Call: OPUS 24 , Panel: NZ7

Principal investigator: Karol Mierzejewski

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

The assessment of purity and identity confirmation of extracellular vesicles withcapillary electrophoresis

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Aleksandra Steć

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

CO-TARGETING OF TUMOR MICROENVIRONMENT-MEDIATED ADAPTATION TO HYPOXIA RENDERS GLIOBLASTOMA MORE SUSCEPTIBLE TO ONCOLYTIC...

Call: OPUS 23 , Panel: NZ5

Principal investigator: dr hab. Agnieszka Marta Bronisz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Analysis of the influence of extracellular follicles from the follicular fluid of the equine ovary on the cumulus cells ...

Call: PRELUDIUM 21 , Panel: NZ9

Principal investigator: Julia Gabryś

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Hodowli i Biologii Zwierząt

The role of PDCD6IP protein from plasma exosomes in progression of melanoma

Call: OPUS 23 , Panel: NZ5

Principal investigator: dr hab. Monika Anna Pietrowska

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Extracellular vesicles modifications for future drug delivery systems

Call: OPUS 23 , Panel: NZ7

Principal investigator: prof. Ewa Łucja Stępień

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Whether, how and which EVs derived from follicular cells can affect boar sperm?

Call: PRELUDIUM BIS 3 , Panel: NZ3

Principal investigator: dr hab. Aneta Andronowska

Instytut Rozrodu Zwierząt i Badań Żywności PAN

Inhibition of protein disulfide isomerases as a strategy for reduction of prothrombotic state in atherosclerosis; therap...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Kamil Przyborowski

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Influence of fungal and bacterial extracellular vesicles on the mechanisms of biofilm formation by pathogenic Candida fu...

Call: SONATA 17 , Panel: NZ6

Principal investigator: dr Justyna Karkowska-Kuleta

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Understanding contribution of platelets and platelet function in epigenetics of Wilson's Disease

Call: SONATA 17 , Panel: NZ2

Principal investigator: dr Ceren Eyileten Postula

Warszawski Uniwersytet Medyczny, Wydział Lekarski

New methods for isolation, separation and characterisation of extracellular vesicles based on the two-dimensional high-p...

Call: SONATA 17 , Panel: ST4

Principal investigator: dr Weronika Maria Hewelt-Belka

Politechnika Gdańska

Extracellular vesicles produced by Bifidobacterium as novel approach fortreatment of allergy diseases

Call: OPUS 22 (LAP) , Panel: NZ7

Principal investigator: dr hab. Sabina Barbara Górska

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Podocyte-specific proteins of extracellular vesicles excreted in the urine as potential markers of graft function after ...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: dr Kornelia Sałaga-Zaleska

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Extracellular vesicles carrying microRNA in experimental immunotherapy for glioblastoma

Call: OPUS 21 , Panel: NZ6

Principal investigator: dr Jakub Godlewski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Mechanisms of generation of myeloid-derived suppressor cells of monocyte origin (Mo-MDSCs) by extracellular vesicles fro...

Call: PRELUDIUM 20 , Panel: NZ6

Principal investigator: dr Izabela Siemińska

Uniwersytet Jagielloński, Collegium Medicum

Extracellular vesicles modified ex vivo as an anti-cancer immune-response boosting vaccine

Call: PRELUDIUM 20 , Panel: NZ6

Principal investigator: Klaudia Elżbieta Kiel

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Analysis of miRNA in extracellular vesicles from respiratory tract associated with asthma pathomechanism in pediatric po...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Dominika Magdalena Ambrożej

Warszawski Uniwersytet Medyczny

Contribution of extracellular vesicles and exosomal arginase to immune dysfunction in endometriosis

Call: OPUS 21 , Panel: NZ6

Principal investigator: dr Małgorzata Maria Czystowska-Kuźmicz

Warszawski Uniwersytet Medyczny

The role of lipid metabolism in transmission of parental traumatic experiences across generations.

Call: SONATA 16 , Panel: NZ3

Principal investigator: dr Ali Jawaid

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Immunomodulatory properties of tumor-derived exosomes from plasma of patients with HPV-dependent and HPV-independent hea...

Call: PRELUDIUM BIS 2 , Panel: NZ4

Principal investigator: dr hab. Monika Anna Pietrowska

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Modulation of exosome production to support anti-cancer treatment

Call: OPUS 18 , Panel: NZ7

Principal investigator: dr Liliana Monika Czernek

Centrum Badań Molekularnych i Makromolekularnych PAN

Molecular and cellular mechanisms of pro-regenerative activity of stem cell- derived extracellular vesicles (EVs) in isc...

Call: MAESTRO 11 , Panel: NZ3

Principal investigator: prof. Ewa Katarzyna Zuba-Surma

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Study of lncRNA differential expression during cardio- and angiogenesis and of molecular mechanisms of their selective p...

Call: OPUS 17 , Panel: NZ3

Principal investigator: dr Marta Hanna Pabiś

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

The role of microRNA delivered by Tumor derived Extracellular Vesicles in modulation of human monocytes activity.

Call: OPUS 17 , Panel: NZ5

Principal investigator: dr hab. Monika Ewa Baj-Krzyworzeka

Uniwersytet Jagielloński, Collegium Medicum

The role of autophagy in the regulation of secretion of extracellular vesicles and proteins at different stages of vascu...

Call: OPUS 16 , Panel: NZ3

Principal investigator: dr hab. Grażyna Krystyna Mosieniak

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Ectosomal alpha-v beta-3 and alpha-v beta-5 as potential proangiogenic factors during melanoma progression

Call: PRELUDIUM 16 , Panel: NZ4

Principal investigator: dr Magdalena Surman

Uniwersytet Jagielloński, Wydział Biologii

Role of microRNAs and prostaglandis in reglation of extracellular vesicles biogenesis in porcine trophoblast cells: in v...

Call: PRELUDIUM 15 , Panel: NZ9

Principal investigator: Maria Marta Guzewska

Instytut Rozrodu Zwierząt i Badań Żywności PAN

BCR-ABL-containing leukemic extracellular vesicles as a novel, immunosuppressive factor controlling function of regulato...

Call: PRELUDIUM 15 , Panel: NZ3

Principal investigator: Julian Marek Swatler

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Interplay between extracellular vesicles and neutrophil extracellular traps during sepsis

Call: PRELUDIUM 15 , Panel: NZ6

Principal investigator: Weronika Ortmann

Uniwersytet Jagielloński, Wydział Biologii

Characterization of secretion, composition and immune properties of the extracellular vesicles released during NLRP3 inf...

Call: SONATINA 2 , Panel: NZ6

Principal investigator: dr Wojciech Marek Cypryk

Centrum Badań Molekularnych i Makromolekularnych PAN