Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Extracellular vesicles as mediators of intercellular communication in an organism exposed to PET microplastics - multi-omic studies in domestic pig model

2022/47/B/NZ7/03026

Keywords:

microplastic PET extracellular vesicles body fluids blood bile urine

Descriptors:

  • NZ7_015:
  • NZ7_002:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Karol Mierzejewski 

Number of co-investigators in the project: 5

Call: OPUS 24 - announced on 2022-07-15

Amount awarded: 1 569 103 PLN

Project start date (Y-m-d): 2023-10-02

Project end date (Y-m-d): 2026-10-01

Project duration:: 36 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Ingested PET microplastics alter the metabolomic profile of the porcine pancreas
    Authors:
    Karol Mierzejewski, Aleksandra Kurzyńska, Monika Golubska, Ismena Gałęcka, Jarosław Całka, Iwona Bogacka
    Academic press:
    Scientific Reports (rok: 2025, tom: 15, strony: 46033), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-025-21915-5 - link to the publication
  2. Extracellular vesicles as mediators of metabolomic changes in response to PET microplastics
    Authors:
    Karol Mierzejewski, Aleksandra Kurzyńska, Monika Golubska, Ismena Gałęcka, Jarosław Całka, Iwona Bogacka.
    Academic press:
    Environmental Pollution (rok: 2025, tom: 385, strony: 46030), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.envpol.2025.127047 - link to the publication
  3. Oral exposure to PET microplastics induces the pancreatic immune response and oxidative stress in immature pigs
    Authors:
    Karol Mierzejewski, Aleksandra Kurzyńska, Monika Golubska, Ismena Gałęcka, Jarosław Całka, Iwona Bogacka
    Academic press:
    BMC Genomics (rok: 2025, tom: 26, strony: 46033), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12864-025-11760-1 - link to the publication