Projects funded by the NCN


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57 projects found matching your search criteria :

  1. The effects of ligands of the alpha7 nicotinic acetylcholine receptors on complex cognitive processes and social behavio...

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Agnieszka Potasiewicz

    Instytut Farmakologii PAN

  2. How does second language proficiency and immersion experience modulate interference between languages? Control mechanism...

    Call: PRELUDIUM 8 , Panel: HS6

    Principal investigator: Joanna Durlik-Marcinowska

    Uniwersytet Jagielloński, Wydział Filozoficzny

  3. Search for the mechanisms of the modulation of canonical Wnt signaling which effectively attenuate the survival of head ...

    Call: SONATA 7 , Panel: NZ7

    Principal investigator: dr Jarosław Paluszczak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  4. Analysis of the structural and functional mechanisms of action of the nicotinic receptors modulators.

    Call: SONATA 5 , Panel: NZ7

    Principal investigator: dr Katarzyna Targowska-Duda

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

  5. The effects of positive allosteric modulators of alpha7 nicotinic acetylcholine receptors on complex cognitive processes...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Nikiforuk

    Instytut Farmakologii PAN

  6. Structural studies based on low sequence similarity of G protein-coupled receptors activated by hormones and allosteric ...

    Call: SONATA 4 , Panel: NZ1

    Principal investigator: dr Dorota Latek

    Uniwersytet Warszawski, Wydział Chemii

  7. Evaluation of the synthesis and metabolism modulation of estrogens - breast cancer risk factors by new synthetic resvera...

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: prof. Wanda Baer-Dubowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  8. The role of corticotropin releasing factor (CRF) in low and high anxiety rats, and teh iteraction between of the CRF sys...

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: dr Anna Skórzewska

    Instytut Psychiatrii i Neurologii

  9. Probing the selectivity of zinc allosteric modulation in various serotonin receptor subtypes

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Grzegorz Satała

    Instytut Farmakologii PAN

  10. Taming aggregation with AmyloGraph 2.0: a database and prediction models of amyloid self-assembly modulators

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Michał Burdukiewicz

    Uniwersytet Medyczny w Białymstoku

  11. Modulation of the N-glycosylation as a tool to improve the CAR-T immunotherapy efficacy

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr Agnieszka Graczyk-Jarzynka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  12. First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: prof. Jadwiga Handzlik

    Uniwersytet Jagielloński, Collegium Medicum

  13. Amorphous Senolytics: A Breakthrough Approach in Senescence Modulation and Age-Related Disease Treatment

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Szymon Sip

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  14. Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Bernadeta Pietrzak-Wawrzyńska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  15. Potential of TH cell profiling in personalized multiple sclerosis treatmentplanning.

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Donskow-Łysoniewska

    Uczelnia Łazarskiego

  16. Histone demethylase inhibitors as chemosensitivity modulators in the treatment of head and neck squamous cell carcinoma

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Dawid Dorna

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  17. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  18. New positive allosteric modulators of EAAT2 glutamate transporter as candidates for treatment of neurological and psychi...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Krzysztof Kamiński

    Uniwersytet Jagielloński, Collegium Medicum

  19. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Przepiórska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  20. 'Mitotherapy as a novel strategy for the modulation of immunometabolic phenotype of fibroblast-like synoviocytes (FLS) –...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Krzysztof Marycz

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Biologii i Hodowli Zwierząt

  21. Targeting UDP-glucose and P2Y14 receptor interaction for therapeutic modulation of inflammatory lung diseases

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Tadeusz Karcz

    Uniwersytet Jagielloński, Collegium Medicum

  22. Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Katarzyna Kieć-Kononowicz

    Uniwersytet Jagielloński, Collegium Medicum

  23. New strategies in the pharmacotherapy of neuropathic pain based on modulation of the chemokine system and its influence ...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Joanna Mika

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  24. Modulation of immune cells activity in the tumor microenvironment by oligonucleotide therapeutics delivered by silk nano...

    Call: OPUS 19 , Panel: NZ6

    Principal investigator: dr hab. Hanna Dams-Kozłowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  25. Exploring new drug targets for efficacious therapy of neuropathic pain basing on the assessment and modulation of neuroi...

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr hab. Joanna Mika

    Instytut Farmakologii PAN

  26. Biotic and abiotic stress elicitors as modulators of isoquinoline alkaloid profile towards specific antimicrobial proper...

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Sylwia Zielińska

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

  27. Modulation of exosome production to support anti-cancer treatment

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Markus Düchler

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  28. SARMs as a modulators of metabolic functions and oxidative stress in adipose and heart tissues in rat obesity model- in ...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Natalia Leciejewska

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  29. Pharmacological modulation of histamine H3 and H4 receptors - a new perspective in the treatment of neuropathic pain

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Katarzyna Popiołek-Barczyk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  30. Galactosylceramide as a regulator of apoptotic gene expression and modulator of drug resistance in breast cancer cells.

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: prof. Maciej Ugorski

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Medycyny Weterynaryjnej

  31. Specific interactions of new antitumor unsymmetrical bisacridines, UAs, with DNA and ABC proteins and their potential to...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: prof. Zofia Mazerska

    Politechnika Gdańska

  32. The role of nitric oxide-dependent pathways in the procognitive effects of muscarinic and metabotropic glutamate recepto...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Joanna Wierońska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  33. Application of machine learning based artificial intelligence to search for substances that modulate the activity of ROR...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Marcin Ratajewski

    Instytut Biologii Medycznej Polskiej Akademii Nauk

  34. The influence of muscarinic acetylcholine receptors (M1, M4 and M5) and serotonergic 5-HT1A receptor modulation on cogni...

    Call: PRELUDIUM 16 , Panel: NZ7

    Principal investigator: dr Paulina Cieślik

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  35. Novel, rationally designed modulators of glycosomal import of enzymes in Trypanosoma parasites

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: dr hab. Maciej Dawidowski

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

  36. Gut microbiota dependent modulation of therapeutic response and side effects to irinotecan and new camptothecin analogue...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Jerzy Ostrowski

    Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy

  37. Prolonged high intensity interval training (HIIT) modulates inflammation through the specific microRNAs level changes in...

    Call: PRELUDIUM 16 , Panel: NZ7

    Principal investigator: Paulina Małczyńska-Sims

    Instytut Psychiatrii i Neurologii

  38. Evaluation of therapeutic role of novel positive allosteric modulators of GABA-A receptor in ischemic brain stroke

    Call: SONATA BIS 8 , Panel: NZ7

    Principal investigator: dr Monika Marcinkowska

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  39. New strategies in neuropathic pain pharmacotherapy based on the modulation of the functions of chemokine receptors CCR2 ...

    Call: PRELUDIUM 15 , Panel: NZ7

    Principal investigator: dr Klaudia Kwiatkowski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  40. Modulation of the structure and properties of curcumin using triterpene oleanolic modifiers

    Call: PRELUDIUM 14 , Panel: NZ7

    Principal investigator: Katarzyna Sowa-Kasprzak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  41. Modulation of inflammatory processes using new agonists of the formyl peptide receptors ALX/FPR2 as a new therapeutic st...

    Call: HARMONIA 9 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  42. Combined urinary bladder cancer treatment with isothiocyanate-derived mercapturic acids and microtubule assembly modulat...

    Call: SONATA 13 , Panel: NZ7

    Principal investigator: dr Mateusz Psurski

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  43. The role of tumor secretable factors in modulation of endothelial senescence cells activity

    Call: SONATA 13 , Panel: NZ7

    Principal investigator: dr Wojciech Ciszewski

    Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu, Katedra Nauk Biomedycznych

  44. Modulation of electrophysiological properties of the spinal cord motoneurons in response to trans-spinal direct current ...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Piotr Krutki

    Akademia Wychowania Fizycznego im. Eugeniusza Piaseckiego w Poznaniu, Wydział Nauk o Zdrowiu

  45. The evaluation of the efficacy of alpha7 nicotinic acetylcholine receptor ligands in rat models of autism

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Nikiforuk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  46. Determination of the mechanisms and potential targets for neuropathic pain therapy by investigating pharmacological inte...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Anna Piotrowska-Murzyn

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  47. Evaluation of SLC22A5 activity modulation in sensitizing glioma cells to the suppression of fatty acid oxidation by CPT1...

    Call: PRELUDIUM 12 , Panel: NZ3

    Principal investigator: Barbara Juraszek

    Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

  48. Old drugs - new perspectives: modulation of antibiotics activity by caffeine and pentoxifylline

    Call: SONATA 11 , Panel: NZ7

    Principal investigator: dr Anna Woziwodzka

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  49. Modulation of the expression and activation of transcription factors Nrf2 and NF-kappaB by new synthetic triterpenoids a...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Wanda Baer-Dubowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  50. New amide derivatives of cinnamic acid as a carbonyl reductase inhibitors, which modulate the activity of doxorubicin - ...

    Call: SONATA 11 , Panel: NZ7

    Principal investigator: dr Paulina Koczurkiewicz-Adamczyk

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny