Projects funded by the NCN

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60 projects found matching your search criteria :

  1. The effects of ligands of the alpha7 nicotinic acetylcholine receptors on complex cognitive processes and social behavio...

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Agnieszka Teresa Potasiewicz

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  2. How does second language proficiency and immersion experience modulate interference between languages? Control mechanism...

    Call: PRELUDIUM 8 , Panel: HS6

    Principal investigator: Joanna Durlik-Marcinowska

    Uniwersytet Jagielloński, Wydział Filozoficzny

  3. Search for the mechanisms of the modulation of canonical Wnt signaling which effectively attenuate the survival of head ...

    Call: SONATA 7 , Panel: NZ7

    Principal investigator: dr Jarosław Jan Paluszczak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  4. Analysis of the structural and functional mechanisms of action of the nicotinic receptors modulators.

    Call: SONATA 5 , Panel: NZ7

    Principal investigator: dr Katarzyna Małgorzata Targowska-Duda

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

  5. The effects of positive allosteric modulators of alpha7 nicotinic acetylcholine receptors on complex cognitive processes...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Anna Nikiforuk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  6. Structural studies based on low sequence similarity of G protein-coupled receptors activated by hormones and allosteric ...

    Call: SONATA 4 , Panel: NZ1

    Principal investigator: dr Dorota Latek

    Uniwersytet Warszawski, Wydział Chemii

  7. Evaluation of the synthesis and metabolism modulation of estrogens - breast cancer risk factors by new synthetic resvera...

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: prof. Wanda Maria Baer-Dubowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  8. The role of corticotropin releasing factor (CRF) in low and high anxiety rats, and teh iteraction between of the CRF sys...

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: dr Anna Karolina Skórzewska

    Instytut Psychiatrii i Neurologii

  9. Probing the selectivity of zinc allosteric modulation in various serotonin receptor subtypes

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Grzegorz Marek Satała

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  10. Modulation of 5-HT7 receptor signaling as common mechanism involved in the long-lasting antidepressant effects of typica...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Barbara Wanda Chruścicka-Smaga

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  11. Modulation of the Gut Microbiome as a Strategy to Counteract Hormone-Dependent Disorders

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Janeczko

    Uniwersytet Przyrodniczy we Wrocławiu

  12. Small molecule modulators of the tumor necrosis factor alpha signaling pathway for the inhibition of inflammatory proces...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Tadeusz Holak

    Uniwersytet Gdański

  13. Molecular mechanisms underlying the liver injury induced by ulipristal acetate treatment

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Aleksandra Natalia Łupińska

    Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

  14. Taming aggregation with AmyloGraph 2.0: a database and prediction models of amyloid self-assembly modulators

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Michał Jan Burdukiewicz

    Uniwersytet Medyczny w Białymstoku

  15. Modulation of the N-glycosylation as a tool to improve the CAR-T immunotherapy efficacy

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr Agnieszka Graczyk-Jarzynka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  16. First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: prof. Jadwiga Handzlik

    Uniwersytet Jagielloński, Collegium Medicum

  17. Amorphous Senolytics: A Breakthrough Approach in Senescence Modulation and Age-Related Disease Treatment

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Szymon Sip

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  18. Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Bernadeta Angelika Pietrzak-Wawrzyńska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  19. Potential of TH cell profiling in personalized multiple sclerosis treatmentplanning.

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Donskow-Łysoniewska

    Uczelnia Łazarskiego

  20. Histone demethylase inhibitors as chemosensitivity modulators in the treatment of head and neck squamous cell carcinoma

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Dawid Dariusz Dorna

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  21. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  22. New positive allosteric modulators of EAAT2 glutamate transporter as candidates for treatment of neurological and psychi...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Krzysztof Tomasz Kamiński

    Uniwersytet Jagielloński, Collegium Medicum

  23. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Barbara Przepiórska-Drońska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  24. Targeting UDP-glucose and P2Y14 receptor interaction for therapeutic modulation of inflammatory lung diseases

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Tadeusz Piotr Karcz

    Uniwersytet Jagielloński, Collegium Medicum

  25. Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Katarzyna Justyna Kieć-Kononowicz

    Uniwersytet Jagielloński, Collegium Medicum

  26. New strategies in the pharmacotherapy of neuropathic pain based on modulation of the chemokine system and its influence ...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Joanna Gabriela Mika

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  27. Modulation of immune cells activity in the tumor microenvironment by oligonucleotide therapeutics delivered by silk nano...

    Call: OPUS 19 , Panel: NZ6

    Principal investigator: prof. Hanna Dams-Kozłowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  28. Exploring new drug targets for efficacious therapy of neuropathic pain basing on the assessment and modulation of neuroi...

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr hab. Joanna Gabriela Mika

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  29. Biotic and abiotic stress elicitors as modulators of isoquinoline alkaloid profile towards specific antimicrobial proper...

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr hab. Sylwia Zielińska

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

  30. Modulation of exosome production to support anti-cancer treatment

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr Liliana Monika Czernek

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  31. SARMs as a modulators of metabolic functions and oxidative stress in adipose and heart tissues in rat obesity model- in ...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: dr Natalia Leciejewska

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  32. Pharmacological modulation of histamine H3 and H4 receptors - a new perspective in the treatment of neuropathic pain

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Katarzyna Popiołek-Barczyk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  33. Galactosylceramide as a regulator of apoptotic gene expression and modulator of drug resistance in breast cancer cells.

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: prof. Maciej Ugorski

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Medycyny Weterynaryjnej

  34. Specific interactions of new antitumor unsymmetrical bisacridines, UAs, with DNA and ABC proteins and their potential to...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: prof. Zofia Mazerska

    Politechnika Gdańska

  35. The role of nitric oxide-dependent pathways in the procognitive effects of muscarinic and metabotropic glutamate recepto...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Joanna Monika Wierońska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  36. Application of machine learning based artificial intelligence to search for substances that modulate the activity of ROR...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Marcin Marek Ratajewski

    Instytut Biologii Medycznej Polskiej Akademii Nauk

  37. The influence of muscarinic acetylcholine receptors (M1, M4 and M5) and serotonergic 5-HT1A receptor modulation on cogni...

    Call: PRELUDIUM 16 , Panel: NZ7

    Principal investigator: dr Paulina Agnieszka Cieślik

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  38. Novel, rationally designed modulators of glycosomal import of enzymes in Trypanosoma parasites

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Maciej Filip Dawidowski

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

  39. Gut microbiota dependent modulation of therapeutic response and side effects to irinotecan and new camptothecin analogue...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Jerzy Zygmunt Ostrowski

    Narodowy lnstytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy lnstytut Badawczy

  40. Prolonged high intensity interval training (HIIT) modulates inflammation through the specific microRNAs level changes in...

    Call: PRELUDIUM 16 , Panel: NZ7

    Principal investigator: Paulina Anna Małczyńska-Sims

    Instytut Psychiatrii i Neurologii

  41. Evaluation of therapeutic role of novel positive allosteric modulators of GABA-A receptor in ischemic brain stroke

    Call: SONATA BIS 8 , Panel: NZ7

    Principal investigator: dr Monika Emilia Marcinkowska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum

  42. New strategies in neuropathic pain pharmacotherapy based on the modulation of the functions of chemokine receptors CCR2 ...

    Call: PRELUDIUM 15 , Panel: NZ7

    Principal investigator: dr Klaudia Kwiatkowski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  43. Modulation of the structure and properties of curcumin using triterpene oleanolic modifiers

    Call: PRELUDIUM 14 , Panel: NZ7

    Principal investigator: Katarzyna Joanna Sowa-Kasprzak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  44. Modulation of inflammatory processes using new agonists of the formyl peptide receptors ALX/FPR2 as a new therapeutic st...

    Call: HARMONIA 9 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  45. Combined urinary bladder cancer treatment with isothiocyanate-derived mercapturic acids and microtubule assembly modulat...

    Call: SONATA 13 , Panel: NZ7

    Principal investigator: dr Mateusz Psurski

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  46. The role of tumor secretable factors in modulation of endothelial senescence cells activity

    Call: SONATA 13 , Panel: NZ7

    Principal investigator: dr Wojciech Michał Ciszewski

    Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

  47. Modulation of electrophysiological properties of the spinal cord motoneurons in response to trans-spinal direct current ...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Piotr Andrzej Krutki

    Akademia Wychowania Fizycznego im. Eugeniusza Piaseckiego w Poznaniu, Wydział Nauk o Zdrowiu

  48. The evaluation of the efficacy of alpha7 nicotinic acetylcholine receptor ligands in rat models of autism

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Anna Nikiforuk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  49. Determination of the mechanisms and potential targets for neuropathic pain therapy by investigating pharmacological inte...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Anna Piotrowska-Murzyn

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  50. Evaluation of SLC22A5 activity modulation in sensitizing glioma cells to the suppression of fatty acid oxidation by CPT1...

    Call: PRELUDIUM 12 , Panel: NZ3

    Principal investigator: Barbara Elżbieta Juraszek

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

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