Search results

1. Identifying changes in Purkinje cell chromatin dynamics as novel drivers of neuronal vulnerability in spinocerebellar at…

Principal investigator: dr Paweł Michał Świtoński

Instytut Chemii Bioorganicznej PAN

Call: OPUS 29, Panel: NZ2

2. Dynamic RNA structures including pseudoknots and G-quadruplexes of influenza type A virus RNAs as targets for designing …

Principal investigator: prof. Elżbieta Beata Kierzek

Instytut Chemii Bioorganicznej PAN

Call: SHENG 4, Panel: NZ1

3. From third ventricle to pituitary gland: regulatory RNA networks in posttranscriptionalmodulation of gene expression in …

Principal investigator: dr Monika Piwecka

Instytut Chemii Bioorganicznej PAN

Call: OPUS 28 (LAP), Panel: NZ3

4. The complex nature of multidomain proteins: the unmasked activity of human Dicer ribonuclease – expect the unexpected

Principal investigator: dr hab. Anna Maria Kurzyńska-Kokorniak

Instytut Chemii Bioorganicznej PAN

Call: OPUS 28, Panel: NZ2

5. Modified nucleotide residues as potential tool to increase aptamer - target protein interaction

Principal investigator: dr Weronika Paulina Kotkowiak

Instytut Chemii Bioorganicznej PAN

Call: SONATA 20, Panel: NZ7

6. A comprehensive structural and functional analysis of toxic RNA-protein interactions for better understanding and therap…

Principal investigator: dr hab. Agnieszka Ludmiła Kiliszek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 28 (LAP), Panel: NZ5

7. Jump in with a splash: Exploring the principles of long noncoding RNA import into mitochondria and its biological releva…

Principal investigator: dr hab. Barbara Uszczyńska-Ratajczak

Instytut Chemii Bioorganicznej PAN

Call: OPUS 27, Panel: NZ3

8. Evaluation of the role of genes BARS1 and BARS2, which encodes novel oxidosqualene synthase, in the natural diversity of…

Principal investigator: dr hab. Agnieszka Jowita Żmieńko

Instytut Chemii Bioorganicznej PAN

Call: OPUS 27, Panel: NZ2

9. Molecular basis of the function of WRKY transcription factors as pivotal regulators of plant responses to stress

Principal investigator: dr Marta Grzechowiak

Instytut Chemii Bioorganicznej PAN

Call: OPUS 27, Panel: NZ9

10. Proteomic predictors of metastasis in colorectal cancer – a validation study

Principal investigator: dr hab. Anna Wojakowska

Instytut Chemii Bioorganicznej PAN

Call: OPUS 27, Panel: NZ5

11. Comprehensive structural and functional analysis of p53 mRNA to identify secondary and tertiary RNA structures important…

Principal investigator: dr Leszek Michał Błaszczyk

Instytut Chemii Bioorganicznej PAN

Call: OPUS 27, Panel: NZ5

12. Unravelling the conservation of crossover hotspots and regulation of meiotic recombination at the pericentromeres

Principal investigator: dr Maja Magdalena Szymańska-Lejman

Instytut Chemii Bioorganicznej PAN

Call: SONATINA 8, Panel: NZ2

13. In search for DNA methylation aberrations associated with susceptibility to ovarian cancer

Principal investigator: dr Malwina Magdalena Suszyńska

Instytut Chemii Bioorganicznej PAN

Call: OPUS 26, Panel: NZ5

14. Insights in the phenylpropanoid transport in model legume plant Medicago truncatula

Principal investigator: dr Wanda Ada Biała-Leonhard

Instytut Chemii Bioorganicznej PAN

Call: SONATA 19, Panel: NZ9

15. At the dawn of Central European statehood on the example of the Czechia and Poland. Dynasties - elites - societies (late…

Principal investigator: prof. Marek Marian Figlerowicz

Instytut Chemii Bioorganicznej PAN

Call: OPUS 26 (LAP), Panel: NZ8

16. Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

Principal investigator: dr hab. Miłosz Ruszkowski

Instytut Chemii Bioorganicznej PAN

Call: SONATA BIS 13, Panel: NZ7

17. (Micro)RNA and informatics approaches for diagnosis, prognosis and treatment of Alzheimer's disease and Dementia

Principal investigator: dr hab. Agnieszka Fiszer

Instytut Chemii Bioorganicznej PAN

Call: JPND Call 2023, Panel: NZ3

18. Antisense oligonucleotides as tools specifically binding viral G-quadruplexes and their experimental verification

Principal investigator: dr Marta Maria Szabat

Instytut Chemii Bioorganicznej PAN

Call: OPUS 25, Panel: ST4

19. Multiomic characterization of neurogenerative processes in Zebrin-II positive and Zebrin-II negative Purkinje cells

Principal investigator: Grażyna Beata Jamróg

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM 22, Panel: NZ3

20. The genetic basis underlying immune resistance in selected accessions of the model plant A. thaliana against the plant p…

Principal investigator: Anastasiia Satyr

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM 22, Panel: NZ2

21. Ultrasensitive profiling of mutations driving tumorigenesis in hereditary syndromes associated with tumor suppressor gen…

Principal investigator: dr Katarzyna Klonowska

Instytut Chemii Bioorganicznej PAN

Call: OPUS 25, Panel: NZ5

22. Functional characterization of ABCG transporters present in Medicago truncatula seeds

Principal investigator: prof. Michał Jasiński

Instytut Chemii Bioorganicznej PAN

Call: OPUS 24, Panel: NZ9

23. tRNA-derived fragments as stress responsive and regulating agents in soybean

Principal investigator: dr hab. Agata Tyczewska

Instytut Chemii Bioorganicznej PAN

Call: OPUS 24, Panel: NZ9

24. Molecular Mechanisms of Dietary Intervention on Neurodegeneration

Principal investigator: dr hab. Maciej Figiel

Instytut Chemii Bioorganicznej PAN

Call: JPND Call 2022, Panel: NZ2

25. Microscopic identification of proteins involved in DNA repair of CAG repeats regions

Principal investigator: dr Mateusz Przemysław Nowaczyk

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM 21, Panel: NZ3

26. Description of the key mechanisms of coordination and prioritization of barley's response to simultaneous biotic and abi…

Principal investigator: dr hab. Anna Barbara Piasecka

Instytut Chemii Bioorganicznej PAN

Call: OPUS 23, Panel: NZ9

27. Crystallographic analysis of RNA-ligand complexes. Towards rational design oflead compounds for development of therapies…

Principal investigator: dr hab. Agnieszka Ludmiła Kiliszek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 23, Panel: NZ7

28. Thermodynamics of modified RNAs. Impact of RNA modifications on structure and function of natural RNA and vaccine-type i…

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 23, Panel: ST4

29. Game of Tails: Understanding the role of 3'-end processing of long noncoding RNAs during zebrafish development

Principal investigator: dr Monika Kwiatkowska

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM 21, Panel: NZ2

30. The puzzling structure of Grainyhead-like human transcription factors involved in tumor growth regulation

Principal investigator: dr Maria Zofia Małecka

Instytut Chemii Bioorganicznej PAN

Call: SONATINA 6, Panel: NZ1

31. The role of transposable elements and epigenetic regulation of gene expression in Medicago truncatula root nodules devel…

Principal investigator: dr hab. Agnieszka Jowita Żmieńko

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM BIS 3, Panel: NZ2

32. Structure-guided design of histone demethylase inhibitors for cancer therapy.

Principal investigator: dr Piotr Henryk Małecki

Instytut Chemii Bioorganicznej PAN

Call: SONATA 17, Panel: NZ7

33. Elucidating neurodegenerative processes using direct profiling of selectively vulnerable neurons

Principal investigator: dr Paweł Michał Świtoński

Instytut Chemii Bioorganicznej PAN

Call: SONATA 17, Panel: NZ3

34. New mechanisms determining MFT-mediated sensitivity to abscisic acid during the germination of Medicago truncatula seeds

Principal investigator: dr hab. Joanna Banasiak

Instytut Chemii Bioorganicznej PAN

Call: OPUS 22, Panel: NZ3

35. Searching for new therapeutic targets in polyglutamine diseases

Principal investigator: prof. Marta Olejniczak

Instytut Chemii Bioorganicznej PAN

Call: OPUS 22, Panel: NZ2

36. Search for Inhibitors of Human δ1-Pyrroline-5-Carboxylate Reductase 1 (PYCR1) as Lead Molecules for the Development of N…

Principal investigator: dr hab. Miłosz Ruszkowski

Instytut Chemii Bioorganicznej PAN

Call: OPUS 22, Panel: NZ7

37. Non-canonical pre-mRNA splicing participates in the editing of CNBP mutant allele in myotonic dystrophy type 2 (DM2)

Principal investigator: dr hab. Marzena Wojciechowska

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM BIS 3, Panel: NZ1

38. Comprehensive phosphoproteomic analysis of NKT cells in the context of the role of phosphorylation mechanisms in progres…

Principal investigator: dr hab. Magdalena Łuczak

Instytut Chemii Bioorganicznej PAN

Call: OPUS 22, Panel: NZ2

39. Functional or not functional? Studying positionally conserved vertebrate lncRNA orthologues at subcellular resolution

Principal investigator: dr hab. Barbara Uszczyńska-Ratajczak

Instytut Chemii Bioorganicznej PAN

Call: SONATA BIS 11, Panel: NZ2

40. Exploring Ty3 genomic RNA structure during retrotransposition in yeast

Principal investigator: dr Angelika Daria Andrzejewska-Romanowska

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM 20, Panel: NZ3

41. Close Encounters of the Third Kind: what happens when ribonuclease Dicer encounters in the cell RNA and DNA adopting G-q…

Principal investigator: dr hab. Anna Maria Kurzyńska-Kokorniak

Instytut Chemii Bioorganicznej PAN

Call: OPUS 21, Panel: NZ2

42. Relationship between ATPase activity stimulation and transport - the case of selective Medicago truncatula ABCG transpor…

Principal investigator: dr Konrad Mateusz Pakuła

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM 20, Panel: NZ1

43. Investigation of a new therapeutic strategy to lower mutant protein in SCA3 / MJD

Principal investigator: prof. Maciej Figiel

Instytut Chemii Bioorganicznej PAN

Call: OPUS 21, Panel: NZ2

44. Investigation of DNA repair mechanisms in DRPLA model using CRISPR-Cas system

Principal investigator: dr Magdalena Dąbrowska

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM 20, Panel: NZ2

45. Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec…

Principal investigator: prof. Elżbieta Beata Kierzek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 21, Panel: NZ1

46. Thrombin binding aptamer with expanded chemical diversity as potential anticoagulant and anticancer agent

Principal investigator: dr Weronika Paulina Kotkowiak

Instytut Chemii Bioorganicznej PAN

Call: OPUS 21, Panel: NZ7

47. The use of artificial miRNAs in the therapy of Huntington's Disease

Principal investigator: dr Anna Kotowska-Zimmer

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM 20, Panel: NZ1

48. The cellular RNA interactome of the human Dicer helicase domain

Principal investigator: dr Kinga Ciechanowska

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM 20, Panel: NZ2

49. Airborne microbiome - characterization of microorganisms inhabiting particulate matter of urban areas and their impact o…

Principal investigator: dr hab. Anna Philips

Instytut Chemii Bioorganicznej PAN

Call: OPUS 21, Panel: NZ9

50. Function and dysfunction of repeated tracts in non-coding and protein-coding transcripts

Principal investigator: dr hab. Agnieszka Fiszer

Instytut Chemii Bioorganicznej PAN

Call: OPUS 21, Panel: NZ3

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