Projects funded by the NCN

Influence of the disorder structure of the transcriptional factor Yin Yang 1 (YY1) on masking effect of the N-terminal a...

Call: PRELUDIUM 1 , Panel: NZ1

Principal investigator: Adam Górka

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

New mechanisms of cellular reprogramming: role of TLR3 and RIG-1 activation and downstream anti-inflammatory response to...

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: dr Jacek Stępniewski

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The assessment of the DNA methylation patterns of PR genes in flax after pathogenic and non-pathogenic Fusarium oxysporu...

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: dr Wioleta Wojtasik

Uniwersytet Wrocławski, Wydział Biotechnologii

The function of SWI/SNF- type chromatin remodeling complexes in control of metabolic processes

Call: OPUS 6 , Panel: NZ1

Principal investigator: dr hab. Tomasz Sarnowski

Instytut Biochemii i Biofizyki PAN

Molecular determinants of interactions between GW182 and CNOT1, proteins involved in miRNA-mediated silencing - identifi...

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: Maja Cieplak-Rotowska

Uniwersytet Warszawski, Wydział Fizyki

Analysis of the role of isoprostanes and their subsequent pathways on the development of cerebral vasospasms in patients...

Call: PRELUDIUM 6 , Panel: NZ4

Principal investigator: Karol Wiśniewski

Uniwersytet Medyczny w Łodzi, II Katedra Chirurgii, Klinika Neurochirurgii i Onkologii Centralnego Układu Nerwowego

Molecular mechanisms of activation and modulation of recombinant GABAA receptors by selected agonists and modulators

Call: OPUS 6 , Panel: NZ3

Principal investigator: prof. Jerzy Mozrzymas

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Lekarski

Synthesis and marking the activity of new potential antagonists of receptors for excitatory amino acids which have the s...

Call: OPUS 1 , Panel: NZ4

Principal investigator: prof. Aleksander Mazurek

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Structural studies of proteases of unknown catalytic type. Establishment of a unique group dedicated to structural studi...

Call: SONATA 1 , Panel: NZ1

Principal investigator: dr Grzegorz Dubin

UNIWERSYTET JAGIELLOŃSKI

The role of DDX5 helicase in the 3' end processing of canonical core histone transcripts in human cells

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: Aleksandra Brzęk

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Super-resolution optical imaging of higher order chromatin structures in nuclei of human cells, during DNA replication a...

Call: OPUS 6 , Panel: NZ3

Principal investigator: prof. Jerzy Dobrucki

Uniwersytet Jagielloński w Krakowie, Wydział Biochemii, Biofizyki i Biotechnologii

Mitochondrial translation-dependent alterations in expression of chloroplast genome and chloroplast to nucleus signallin...

Call: SONATA 6 , Panel: NZ1

Principal investigator: dr Małgorzata Kwaśniak-Owczarek

Uniwersytet Wrocławski, Wydział Biotechnologii

Molecular and biochemical characterization of eukaryotic C9orf41 protein.

Call: OPUS 6 , Panel: NZ1

Principal investigator: dr Jakub Drożak

Uniwersytet Warszawski, Wydział Biologii

Function of prenyllipids in development and plant stress response

Call: OPUS 1 , Panel: NZ1

Principal investigator: prof. Jerzy Kruk

UNIWERSYTET JAGIELLOŃSKI, Wydział Biochemii, Biofizyki i Biotechnologii

Exploring the Mutual Interactions between RNA Enantiomers

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: Marta Dudek

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Phenotypic plasticity of human macrophages regulating angiogenesis and lymphangiogenesis. The influence of exogenous fac...

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: Radosław Olkowski

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

The comprehensive assessment of fibrin clot function and structure in patients taking oral anticoagulants

Call: PRELUDIUM 1 , Panel: NZ4

Principal investigator: Michał Ząbczyk

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

Involvement of SnRK2 kinases in regulation of redox status in plant response to environmental stress

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: dr Katarzyna Szymańska

Instytut Biochemii i Biofizyki PAN

Investigation of amino acid linker-specific dependence of electron transfer between cytochrome c553 and photosystem I fr...

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: Julian Janna Olmos

Uniwersytet Warszawski, Wydział Biologii

Nickel oxides and metallic nickel as nickel(II) ion sources for nicklel(II)-assisted hydrolysis of peptide bond

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: Nina Wezynfeld

Instytut Biochemii i Biofizyki PAN

Essential features of miRNA precursors required for release of homogenous siRNAs from shRNA-miR vectors.

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: dr Paulina Gałka-Marciniak

Instytut Chemii Bioorganicznej PAN

Mutations in mitochondrial ATP6 gene, identified in cancer and myopathies, and their impact on ATP synthase and cell met...

Call: OPUS 6 , Panel: NZ1

Principal investigator: dr hab. Róża Kucharczyk

Instytut Biochemii i Biofizyki PAN

Extramitochondrial factors regulating turnover of mitochondrial intermembrane space proteins

Call: SONATA 6 , Panel: NZ1

Principal investigator: dr Piotr Brągoszewski

Uniwersytet Warszawski

Mechanism and consequences of protein N-homocysteinylation in humans

Call: OPUS 6 , Panel: NZ1

Principal investigator: prof. Hieronim Jakubowski

Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa i Bioinżynierii

Post-translational mechanisms of regulation of the activity of transcription factors from the Grainyhead-like family in ...

Call: OPUS 6 , Panel: NZ1

Principal investigator: dr hab. Tomasz Wilanowski

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Molecular functions of the human SUV3 gene

Call: OPUS 6 , Panel: NZ1

Principal investigator: prof. Piotr Stępień

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Function of antioxidant prenyllipids in response of green-algae Chlamydomonas reinhardtii to stress induced by heavy met...

Call: SONATA 6 , Panel: NZ1

Principal investigator: dr Beatrycze Nowicka

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Toxicokinetics study and imaging of temporal and spatial distribution of titanium in internal structure of selected orga...

Call: PRELUDIUM 6 , Panel: NZ4

Principal investigator: Magdalena Golasik

Uniwersytet Jagielloński, Wydział Chemii

A role of U12-type introns in eukaryotic gene expression regulation

Call: OPUS 6 , Panel: NZ1

Principal investigator: prof. Zofia Szweykowska-Kulińska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Protein stability in aqueous solutions of osmolytes studied through complementary theoretical and experimental approach

Call: OPUS 6 , Panel: NZ1

Principal investigator: prof. Janusz Stangret

Politechnika Gdańska, Wydział Chemiczny

Benzoic synthesis in flax

Call: OPUS 6 , Panel: NZ1

Principal investigator: prof. Jan Szopa-Skórkowski

Uniwersytet Wrocławski, Wydział Biotechnologii

Synthesis, biological and biophysical evaluation of mRNA cap-peptide conjugates for targeted delivery of cap analogues t...

Call: OPUS 6 , Panel: ST5

Principal investigator: dr hab. Marzena Jankowska-Anyszka

Uniwersytet Warszawski, Wydział Chemii

The crosstalk between the microRNA biogenesis complex, splicing and polyadenylation machineries in plants

Call: MAESTRO 5 , Panel: NZ1

Principal investigator: prof. Artur Jarmołowski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Inhibitors of ER stress dependant PERK kinase as a novel approach for Alzheimer's therapy

Call: HARMONIA 5 , Panel: NZ1

Principal investigator: prof. Ireneusz Majsterek

Uniwersytet Medyczny w Łodzi, Wydział Wojskowo-Lekarski

An integrated approach to the prediction of the structures of proteins and protein complexes with the use of the coarse-...

Call: HARMONIA 5 , Panel: ST4

Principal investigator: prof. Józef Liwo

Uniwersytet Gdański, Wydział Chemii

Role of the gates and anchoring residues in enzymes activity and selectivity.

Call: SONATA BIS 3 , Panel: NZ1

Principal investigator: dr Artur Góra

Politechnika Śląska, Centrum Biotechnologii

The effect of ppGpp analogs on RNA polymerase in the aspect of prokariotic and eukariotic transcriptional factors.

Call: SONATA BIS 3 , Panel: NZ1

Principal investigator: dr hab. Katarzyna Potrykus

Uniwersytet Gdański, Wydział Biologii

Exploiting the potential of synchrotron radiation for high resolution and weak signal in macromolecular crystallography

Call: HARMONIA 5 , Panel: NZ1

Principal investigator: prof. Mariusz Jaskólski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Thermodynamic insights into design of functionally optimized modified siRNAs and their experimental verification.

Call: SONATA BIS 3 , Panel: NZ1

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej PAN

Characterizing the functions of plant PCNA1 and PCNA2 proteins using Arabidopsis thaliana as an experimental model

Call: SONATA BIS 3 , Panel: NZ1

Principal investigator: dr Wojciech Strzałka

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Building bacterial orisome on bipartite origins - structural, functional and regulatory aspects of the process based on ...

Call: SONATA BIS 3 , Panel: NZ1

Principal investigator: dr hab. Anna Pawlik

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

The role of homologous recombination DNA repair mediators in the maintenance of centromere integrity.

Call: HARMONIA 5 , Panel: NZ1

Principal investigator: dr hab. Dorota Dziadkowiec

Uniwersytet Wrocławski, Wydział Biotechnologii

Functional analysis of Staphylococcus aureus antisig-sig operon

Call: PRELUDIUM 1 , Panel: NZ1

Principal investigator: Michał Bukowski

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Is size so crucial? Complex examination of plankton size structure in the warming European Arctic

Call: OPUS 5 , Panel: NZ8

Principal investigator: dr hab. Katarzyna Błachowiak-Samołyk

Instytut Oceanologii Polskiej Akademii Nauk

The active center and beyond: towards new selective inhibitors of S-adenosyl-L-homocysteine hydrolase. Structural enzymo...

Call: OPUS 5 , Panel: NZ1

Principal investigator: dr Krzysztof Brzeziński

Uniwersytet w Białymstoku, Wydział Biologiczno-Chemiczny

Functional and biochemical characterization of human Rexo2 and FASTKD3 proteins

Call: PRELUDIUM 5 , Panel: NZ1

Principal investigator: Maciej Szewczyk

Uniwersytet Warszawski, Wydział Biologii

Structural basis of biological properties of muscle fructose-1,6-bisphosphatase (FBPase) - a regulatory enzyme of glycon...

Call: OPUS 5 , Panel: NZ1

Principal investigator: prof. Andrzej Dżugaj

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Identification of apple sRNAs involved in Fire Blight resistance.

Call: PRELUDIUM 5 , Panel: NZ1

Principal investigator: Elżbieta Kaja

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

BCL11b - Potential Therapeutic Target in T cell Neoplasms

Call: OPUS 5 , Panel: NZ1

Principal investigator: dr hab. Grzegorz Przybylski

Instytut Genetyki Człowieka PAN

Evolutionary modeling physicochemical conditions for overexpression of viral replicons in plant liquid cultures

Call: SONATA 5 , Panel: NZ1

Principal investigator: dr Radosław Pilarski

Instytut Chemii Bioorganicznej PAN