Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Molecular determinants of interactions between GW182 and CNOT1, proteins involved in miRNA-mediated silencing - identification of key protein fragments and their conformational changes determining molecular recognition.

2013/11/N/NZ1/02387

Keywords:

miRNA regulation of gene expression GW182 TNRC6C silencing domain CNOT1 protein-protein interactions mass spectrometry natively unstructured proteins hydrogen-deuterium exchange conformational changes

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_3: Biophysics
  • NZ1_2: Biochemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Warszawski, Wydział Fizyki

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Maja Cieplak-Rotowska 

Number of co-investigators in the project: 3

Call: PRELUDIUM 6 - announced on 2013-09-16

Amount awarded: 99 970 PLN

Project start date (Y-m-d): 2014-09-10

Project end date (Y-m-d): 2017-09-09

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled