Projects funded by the NCN

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61 projects found matching your search criteria :

  1. The role of the P2X4 purinergic receptor in regulating mitochondrial metabolism and redox homeostasis in hematopoietic s...

    Call: PRELUDIUM 24 , Panel: NZ3

    Principal investigator: Magda Molenda

    Warszawski Uniwersytet Medyczny

  2. Modulation of 5-HT7 receptor signaling as common mechanism involved in the long-lasting antidepressant effects of typica...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Barbara Wanda Chruścicka-Smaga

    Instytut Farmakologii PAN

  3. Understanding the function of DTX3L ligase in an antiviral response induced by pattern recognition receptors (PRR).

    Call: OPUS 27 , Panel: NZ3

    Principal investigator: dr hab. Jakub Maciej Siednienko

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  4. Mitochondrial metabolism of glycerol as a regulator of lymphocyte homeostasis and pathology

    Call: OPUS 27 , Panel: NZ6

    Principal investigator: dr Marcin Kaminski

    Politechnika Śląska

  5. Targeting Proteinopathies: Understanding and Mitigating the Effects of Pathogenic Mutations in Cullin-RING Ubiquitin Lig...

    Call: OPUS 27 , Panel: NZ3

    Principal investigator: dr hab. Wojciech Mieczysław Pokrzywa

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  6. Deciphering the importance of the intracellular FGFR1 module for cell fate

    Call: OPUS 26 , Panel: NZ1

    Principal investigator: dr hab. Małgorzata Urszula Zakrzewska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  7. Evaluation of P2X7 purinergic receptor as a trigger of brain metabolic abnormalities and neuronal degeneration in a mous...

    Call: SONATA BIS 13 , Panel: NZ4

    Principal investigator: dr Anna Wilkaniec

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  8. Actin cytoskeleton disorders as a pro-survival signaling activator and a therapeutic biomarker in Diffuse Large B-cell L...

    Call: SONATA BIS 13 , Panel: NZ5

    Principal investigator: dr Patryk Górniak

    Instytut Hematologii i Transfuzjologii

  9. INVADOPODIA IN AXL-DRIVEN CANCER INVASION AND DRUG RESISTANCE

    Call: OPUS 25 , Panel: NZ3

    Principal investigator: dr Daria Paulina Zdżalik-Bielecka

    Uniwersytet Warszawski, Wydział Biologii

  10. Proinsulin C-peptide and G protein-coupled receptor 146 (GPR146) – clinical investigation of the impact of their signall...

    Call: PRELUDIUM 21 , Panel: NZ4

    Principal investigator: Aleksandra Ryk

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  11. Use of comparative oncology approach to dissect the PD-1 intrinsic signalling in osteosarcoma. Can dog be the key for ne...

    Call: PRELUDIUM 21 , Panel: NZ1

    Principal investigator: Katarzyna Joanna Dziubek

    Uniwersytet Gdański, Międzynarodowe Centrum Badań nad Szczepionkami Przeciwnowotworowymi

  12. Yin and Yang effect of P2X and P1 purinergic receptors on compartment of hematopoietic stem cells

    Call: OPUS 23 , Panel: NZ3

    Principal investigator: prof. Magdalena Józefa Kucia

    Warszawski Uniwersytet Medyczny

  13. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Barbara Przepiórska-Drońska

    Instytut Farmakologii PAN

  14. Development of the knowledge on the role of GPR18 ligands as a microglia-targeted strategy in the regulation of neuroinf...

    Call: SONATA 17 , Panel: NZ3

    Principal investigator: dr Ewelina Barbara Honkisz-Orzechowska

    Uniwersytet Jagielloński, Collegium Medicum

  15. The role of ATP-dependent activation of P2 purinergic receptors in the energetic disturbances in the brain of autistic-l...

    Call: PRELUDIUM 20 , Panel: NZ4

    Principal investigator: Lidia Maria Babiec

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  16. Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  17. AXL receptor signaling in cancer cell growth and drug resistance

    Call: OPUS 20 , Panel: NZ3

    Principal investigator: prof. Marta Elżbieta Miączyńska

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  18. Expression and function of Regulator of G Protein Signaling (RGS) proteins in physiological and pathophysiological condi...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr hab. Maciej Stawnisław Sałaga

    Uniwersytet Medyczny w Łodzi

  19. Structure-function relationship in fibroblast growth factor signaling

    Call: CEUS-UNISONO , Panel: NZ3

    Principal investigator: dr hab. Małgorzata Urszula Zakrzewska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  20. In vivo effects, underlying signaling pathways and mechanism of action of ghrelin receptor agonist against pathological ...

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Piotr Chmielarz

    Instytut Farmakologii PAN

  21. Kappa opioid receptors integrate neuronal signaling involved in social behavior

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii PAN

  22. Extracellular galectins as controllers of fibroblast growth factor receptor signaling

    Call: SONATA BIS 9 , Panel: NZ3

    Principal investigator: dr Łukasz Opaliński

    Uniwersytet Wrocławski, Wydział Biotechnologii

  23. The EBI2 receptor/oxysterol signalling in multiple sclerosis pathophysiology, therapy and diagnostics.

    Call: OPUS 17 , Panel: NZ4

    Principal investigator: dr Aleksandra Rutkowska

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  24. Biased multi-target ligands as tools for activity pattern analysis of G protein-coupled receptors in cancer cells

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr Artur Wnorowski

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

  25. Does DREADD and TrkB gene transfer targeted to selected motoneurons following spinal cord injury bring recovery of motor...

    Call: OPUS 16 , Panel: NZ4

    Principal investigator: prof. Małgorzata Hanna Skup

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  26. Badanie funkcji białek homologicznych do czynników wzrostu fibroblastów (FHF)

    Call: OPUS 16 , Panel: NZ3

    Principal investigator: dr hab. Małgorzata Urszula Zakrzewska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  27. Role of astrocytic NMDA receptors in the regulation of glutamine synthetase activity in cultured mouse astrocytes. Attem...

    Call: PRELUDIUM 14 , Panel: NZ3

    Principal investigator: dr Katarzyna Skowrońska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  28. The influence of impairment of extracellular nucleoside and nucleotide signaling on synaptic structure and function in a...

    Call: OPUS 13 , Panel: NZ4

    Principal investigator: dr hab. Agata Adamczyk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  29. Intracellular cross-talk between ligands and Notch receptors determine signalling response

    Call: OPUS 13 , Panel: NZ4

    Principal investigator: prof. Adolfo Rivero-Muller

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  30. Crosstalk between fibroblast growth factor receptors signaling and regulation of vitamin D receptor in leukemogenesis.

    Call: OPUS 12 , Panel: NZ5

    Principal investigator: prof. Ewa Teresa Marcinkowska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  31. Molecular identification of signalling pathways activated by receptor kinase CRK5 during senescence and stress response ...

    Call: SONATA 12 , Panel: NZ1

    Principal investigator: dr Paweł Burdiak

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  32. The role of codependent 5-HT1a and 5-HT7 receptor signalling in the hippocampal stress response

    Call: PRELUDIUM 12 , Panel: NZ4

    Principal investigator: Marcin Siwiec

    Instytut Farmakologii PAN

  33. Structural studies of signaling receptors HVEM/CD160 as potential targets for immunoterapy against melanoma

    Call: SONATA 11 , Panel: NZ1

    Principal investigator: dr Marta Orlikowska

    Uniwersytet Gdański, Wydział Chemii

  34. The impact of intracellular distribution and endocytic transport of lymphotoxin beta receptor (LTbetaR) on its signaling

    Call: OPUS 11 , Panel: NZ3

    Principal investigator: dr Magdalena Maria Banach-Orłowska

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  35. Neurodevelopmental patomechanisms of triclocarban- and dichlorodiphenyldichloroetylene-induced effects: the role of apop...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Kajta

    Instytut Farmakologii PAN

  36. Molecular mechanism of interactions between GPCRs and G protein.

    Call: PRELUDIUM 10 , Panel: NZ2

    Principal investigator: Stefan Mateusz Mordalski

    Instytut Farmakologii PAN

  37. Mechanism of epigenetic-driven inactivation of tumor suppressor SIGIRR

    Call: OPUS 10 , Panel: NZ6

    Principal investigator: dr Katarzyna Bulek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  38. Endocytosis of AXL receptor and its role in AXL-mediated signaling.

    Call: SONATA 10 , Panel: NZ3

    Principal investigator: dr Daria Paulina Zdżalik-Bielecka

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  39. Molecular mechanisms of nucleic acids receptors signalling regulation by Pellino 3 protein during viral infection.

    Call: SONATA BIS 5 , Panel: NZ3

    Principal investigator: dr hab. Jakub Maciej Siednienko

    Wrocławskie Centrum Badań EIT+ Sp. z o.o.

  40. Estrogen signaling in male gonad from birth to aging. Study of the molecular mechanisms of cellular processes in mammali...

    Call: SONATA BIS 5 , Panel: NZ4

    Principal investigator: dr hab. Małgorzata Aneta Kotula-Balak

    Uniwersytet Jagielloński, Wydział Biologii

  41. Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Irena Maria Nalepa

    Instytut Farmakologii PAN

  42. Extracellular nucleotide gradients as regulators of glioma cell motility

    Call: OPUS 9 , Panel: NZ3

    Principal investigator: dr hab. Paweł Pomorski

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  43. Estrogen receptor GPER as a modulator of inflammatory and functional gastrointestinal diseases and colorectal cancer

    Call: PRELUDIUM 9 , Panel: NZ5

    Principal investigator: Damian Jacenik

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  44. Relatioship between activation of FGFR-mediated signalling and loss of progesterone receptor in estrogen receptor-positi...

    Call: OPUS 9 , Panel: NZ4

    Principal investigator: prof. Radzisław Kordek

    Uniwersytet Medyczny w Łodzi, Katedra Onkologii, Zakład Patologii

  45. Molecular mechanism of unique action of clozapine in the context of GPCR.

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: dr Agata Faron-Górecka

    Instytut Farmakologii PAN

  46. The role of urokinase-type plasminogen activator receptor in the process of endothelial microparticle formation and inte...

    Call: PRELUDIUM 8 , Panel: NZ5

    Principal investigator: Martyna Maria Durak-Kozica

    Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  47. The role of lysophosphatidic (LPA) and sphingosine-1-phosphate (S1P) and their receptors in human endometrial stromal ce...

    Call: PRELUDIUM 7 , Panel: NZ4

    Principal investigator: Maria Sztachelska

    Instytut Rozrodu Zwierząt i Badań Żywności PAN

  48. Lyn tyrosine kinase as regulator of lipopolysaccharide-triggered TLR4 pro-inflammatory signaling

    Call: PRELUDIUM 7 , Panel: NZ3

    Principal investigator: dr Kinga Borzęcka-Solarz

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  49. Stearoyl-CoA desaturase and intracellular lipid signaling as novel players in regulation of thyroid hormone action in th...

    Call: OPUS 7 , Panel: NZ4

    Principal investigator: dr hab. Paweł Dobrzyń

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  50. The role of ceramide and sphingosine-1-phosphate receptor signalling in amyloid beta precursor protein metabolism.

    Call: PRELUDIUM 6 , Panel: NZ4

    Principal investigator: dr Kinga Sylwia Czubowicz

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

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