Projects funded by the NCN

2-oxoglutarate dependent oxygenases catalyzing atypical oxidative transformations - structural and mechanistic studies.

Call: OPUS 8 , Panel: NZ1

Principal investigator: prof. Tomasz Borowski

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Selective recognition of toxic heteroaromatic amines and N-nitrosamines in protein providing food products

Call: OPUS 8 , Panel: NZ7

Principal investigator: prof. Włodzimierz Kutner

Instytut Chemii Fizycznej PAN

Biodegradable poly(N-vinylpyrrolidone) hydrogels containing trehalose as bioprotective protein carriers

Call: PRELUDIUM 8 , Panel: ST8

Principal investigator: Małgorzata Burek

Politechnika Śląska, Wydział Chemiczny

New and efficient methods for the flexible molecular docking of proteins.

Call: MAESTRO 6 , Panel: ST6

Principal investigator: prof. Andrzej Koliński

Uniwersytet Warszawski, Wydział Chemii

Materials determinants of biological activity of new generation simple and composite bioactive materials.

Call: OPUS 7 , Panel: ST8

Principal investigator: prof. Maria Borczuch-Łączka

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Inżynierii Materiałowej i Ceramiki

Middle ear dynamics with smart prosthesis

Call: OPUS 7 , Panel: ST8

Principal investigator: dr hab. Rafał Rusinek

Politechnika Lubelska, Wydział Mechaniczny

Refolding of protein in membrane and chromatographic reactor

Call: PRELUDIUM 6 , Panel: ST8

Principal investigator: Sylwia Ryś

Politechnika Rzeszowska im. Ignacego Łukasiewicza, Wydział Chemiczny

Modeling realistic tear film structure including tear protein and analyzing its role in stability and biophysical proper...

Call: PRELUDIUM 6 , Panel: ST7

Principal investigator: Alicja Wizert

Politechnika Wrocławska, Wydział Podstawowych Problemów Techniki

An integrated approach to the prediction of the structures of proteins and protein complexes with the use of the coarse-...

Call: HARMONIA 5 , Panel: ST4

Principal investigator: prof. Józef Liwo

Uniwersytet Gdański, Wydział Chemii

Structural basis of biological properties of muscle fructose-1,6-bisphosphatase (FBPase) - a regulatory enzyme of glycon...

Call: OPUS 5 , Panel: NZ1

Principal investigator: prof. Andrzej Dżugaj

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Simulation of conformational changes related to the interdomain communication in the eukaryotic GlcN-6-P synthase by mea...

Call: PRELUDIUM 5 , Panel: NZ2

Principal investigator: Aleksandra Miszkiel

Politechnika Gdańska, Wydział Chemiczny

Structural analysis of substrate binding region of Hsp40 protein

Call: PRELUDIUM 5 , Panel: NZ2

Principal investigator: Maciej Baranowski

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

A novel continuous method of proteolysis in hierarchically structured microreactor

Call: SONATA 5 , Panel: ST8

Principal investigator: dr Katarzyna Szymańska

Politechnika Śląska, Wydział Chemiczny

Synthetic, new generation layers to interact with the liquid connective tissue

Call: OPUS 5 , Panel: ST8

Principal investigator: dr hab. Aleksandra Wesełucha-Birczyńska

Uniwersytet Jagielloński, Wydział Chemii

Electrospinning of bicomponent nanofibers - synthetic polymer/biopolymer using alternative, protein non-denaturing, nonc...

Call: OPUS 5 , Panel: ST8

Principal investigator: dr hab. Paweł Sajkiewicz

Instytut Podstawowych Problemów Techniki PAN

Virtual High Throughput Screening (vHTS) derivation of a cross-immunity model for the Influenza-A Virus Infections.

Call: OPUS 5 , Panel: NZ2

Principal investigator: dr hab. Dariusz Plewczyński

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Designing mRNA transcripts resistant to enzymatic cap hydrolysis applicable for anti-cancer vaccines; multiplexed bioche...

Call: MAESTRO 4 , Panel: NZ1

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Centrum Nowych Technologii

Bioinformatic analysis of GmrSD, a Type IV Modification-Dependent Restriction Systems

Call: PRELUDIUM 4 , Panel: NZ2

Principal investigator: Magdalena Machnicka

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Halogen Bonding in Protein-Ligand Complexes. Thermodynamics and Structural Studies on Rationally Selected Protein-Ligand...

Call: OPUS 4 , Panel: ST4

Principal investigator: prof. Jarosław Poznański

Instytut Biochemii i Biofizyki PAN

Structural studies based on low sequence similarity of G protein-coupled receptors activated by hormones and allosteric ...

Call: SONATA 4 , Panel: NZ1

Principal investigator: dr Dorota Latek

Uniwersytet Warszawski, Wydział Chemii

Revealing adsorption mechanisms of anisotropic proteins under well-defined transport conditions.

Call: OPUS 4 , Panel: ST4

Principal investigator: prof. Zbigniew Adamczyk

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Members of eIF4E protein family, their affinities towards 5' mRNA cap and protein binding partners: an interdisciplinary...

Call: OPUS 4 , Panel: NZ1

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Wydział Fizyki

Mechanics of single molecules: REELIN - neuronal growth steering protein.

Call: PRELUDIUM 3 , Panel: ST3

Principal investigator: dr Karolina Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Analysis of the plasma proteome in chronic kidney disease in the context of progressive cardiovascular disease.

Call: OPUS 3 , Panel: NZ2

Principal investigator: dr Magdalena Łuczak

Instytut Chemii Bioorganicznej PAN

The study of new safer cross-linking methods of protein materials for tissue engineering

Call: SONATA 2 , Panel: ST8

Principal investigator: dr Joanna Skopińska-Wiśniewska

UNIWERSYTET MIKOŁAJA KOPERNIKA W TORUNIU, Wydział Chemii

Structure and function of acireductone dioxygenases - experimental and computational studies.

Call: OPUS 2 , Panel: NZ1

Principal investigator: dr hab. Tomasz Borowski

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Exposing unseen passages - towards identification of functional transient tunnels in protein structures

Call: PRELUDIUM BIS 5 , Panel: NZ2

Principal investigator: dr hab. Jan Brezovský

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Optimization of coarse-grained molecular dynamics simulations for tunnel exploration of large proteins with buried activ...

Call: PRELUDIUM 22 , Panel: NZ2

Principal investigator: Nishita Mandal

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Modeling the effect of climate change and soil organic carbon on baking quality traits of winter wheat cultivars in temp...

Call: PRELUDIUM 22 , Panel: NZ9

Principal investigator: Abu Zar Ghafoor

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Rolnictwa

Decrypting the "sulfation code" of glycosaminoglycans for understanding their function in the extracellular matrix

Call: OPUS 25 , Panel: ST4

Principal investigator: dr hab. Sergey Samsonov

Uniwersytet Gdański, Wydział Chemii

Study of ligand binding and activation processes of formyl, opioid and cannabinoid G-protein-coupled receptors

Call: OPUS 2 , Panel: NZ1

Principal investigator: prof. Sławomir Filipek

Uniwersytet Warszawski, Wydział Chemii

Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap...

Call: SONATA BIS 12 , Panel: ST4

Principal investigator: dr Karolina Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Rational engineering of E. coli penicillin G acylase for quorum quenching-based bacterial control as an effective strate...

Call: PRELUDIUM 20 , Panel: NZ2

Principal investigator: Bartłomiej Surpeta

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Integrative methods for modeling protein-protein complexes and multimolecular assemblies

Call: SHENG 2 , Panel: NZ2

Principal investigator: dr hab. Sebastian Kmiecik

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Data-assisted modeling of the ensemble structure of intrinsically disordered proteins and their assemblies

Call: SHENG 2 , Panel: ST4

Principal investigator: prof. Józef Liwo

Uniwersytet Gdański, Wydział Chemii

Purification and isolation of proteins in integrated process of extraction and chromatography

Call: PRELUDIUM 2 , Panel: ST8

Principal investigator: Wojciech Marek

Politechnika Rzeszowska im. Ignacego Łukasiewicza, Wydział Chemiczny

Self-learning systems in the design of compounds modulating GPCR receptors activation.

Call: OPUS 20 , Panel: NZ2

Principal investigator: dr hab. Dorota Latek

Uniwersytet Warszawski, Wydział Chemii

Blocking HVEM/LIGHT interactions using peptides - an innovative approach to immunosuppression

Call: PRELUDIUM BIS 2 , Panel: ST4

Principal investigator: dr hab. Adam Sieradzan

Uniwersytet Gdański, Wydział Chemii

Development of tools for the rational design of peptide therapeutics

Call: OPUS 20 , Panel: NZ2

Principal investigator: dr hab. Sebastian Kmiecik

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Identification and comprehensive classification of peptidases

Call: SONATA 15 , Panel: NZ2

Principal investigator: dr Kamil Steczkiewicz

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Molecular mechanisms, signal transduction and inhibition of PEBP1-15LOX protein complex triggering the ferroptotic cell ...

Call: SONATA 15 , Panel: ST4

Principal investigator: dr Karolina Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Development of a new protein-protein docking method based on the flexible docking of short peptide fragments.

Call: OPUS 17 , Panel: NZ2

Principal investigator: dr Mateusz Kurciński

Uniwersytet Warszawski

Influence of polyester fiber and chemical finishing agents on thermally-assisted acidic hydrolysis of natural fibers con...

Call: OPUS 17 , Panel: ST8

Principal investigator: dr hab. Izabela Witońska

Politechnika Łódzka, Wydział Chemiczny

Mechanistic insights into the specificity of glycosaminoglycan interactions with regulatory proteins

Call: BEETHOVEN 3 , Panel: ST4

Principal investigator: dr hab. Sergey Samsonov

Uniwersytet Gdański, Wydział Chemii

Crystallization of monoclonal antibodies by forced convection evaporation

Call: PRELUDIUM 16 , Panel: ST8

Principal investigator: Michał Kołodziej

Politechnika Rzeszowska im. Ignacego Łukasiewicza, Wydział Chemiczny

Modeling of glycosaminoglycan-induced formation of protein structure and enhancement of biologically relevant protein-li...

Call: SONATA BIS 8 , Panel: ST4

Principal investigator: dr Sergey Samsonov

Uniwersytet Gdański, Wydział Chemii

Combining Rosetta method with deeply coarse grained SURPASS model into a novel multiscale algorithm for modeling protein...

Call: OPUS 15 , Panel: ST6

Principal investigator: dr hab. Dominik Gront

Uniwersytet Warszawski, Wydział Chemii

Extension of the CABS-dock method for protein-peptide docking to modelling of membrane proteins

Call: PRELUDIUM 15 , Panel: NZ1

Principal investigator: Maciej Ciemny

Uniwersytet Warszawski, Wydział Chemii

The role and cooperation of AidB dehydrogenase and AlkB dioxygenase in repair of adducts to DNA and RNA bases

Call: OPUS 15 , Panel: NZ3

Principal investigator: dr hab. Agnieszka Maciejewska

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Analysis of physical - chemical and thermal processes which determine the structure of casting metallic biomaterials.

Call: PRELUDIUM 1 , Panel: ST8

Principal investigator: Karolina Beer-Lech

Politechnika Lubelska, Wydział Mechaniczny