Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Integrative methods for modeling protein-protein complexes and multimolecular assemblies

2021/40/Q/NZ2/00078

Keywords:

protein-protein docking coarse-grained modeling multiscale modeling molecular docking

Descriptors:

  • NZ2_10: Biological systems analysis, modelling and simulation
  • NZ2_7: Bioinformatics
  • NZ2_8: Computational biology

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Sebastian Kmiecik 

Number of co-investigators in the project: 6

Call: SHENG 2 - announced on 2020-12-15

Amount awarded: 1 918 816 PLN

Project start date (Y-m-d): 2021-12-22

Project end date (Y-m-d): 2025-07-21

Project duration:: 43 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. A3D Model Organism Database (A3D-MODB): a database for proteome aggregation predictions in model organisms
    Authors:
    Aleksandra E Badaczewska-Dawid, Aleksander Kuriata, Carlos Pintado-Grima, Javier Garcia-Pardo, Michał Burdukiewicz, Valentín Iglesias, Sebastian Kmiecik, Salvador Ventura
    Academic press:
    Nucleic Acids Research (rok: 2023, tom: 52, D1, strony: D360–D367), Wydawca: Oxford academic
    Status:
    Published
    DOI:
    10.1093/nar/gkad942 - link to the publication
  2. A3DyDB: exploring structural aggregation propensities in the yeast proteome
    Authors:
    Javier Garcia-Pardo, Aleksandra E. Badaczewska-Dawid, Carlos Pintado-Grima, Valentín Iglesias, Aleksander Kuriata, Sebastian Kmiecik, Salvador Ventura
    Academic press:
    Microbial Cell Factories (rok: 2023, tom: 22, strony: 186), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12934-023-02182-3 - link to the publication
  3. Efficient improvement of the proliferation, differentiation, and anti-arthritic capacity of mesenchymal stem cells by simply culturing on the immobilized FGF2 derived peptide, 44-ERGVVSIKGV-53
    Authors:
    Soo Bin Lee, Ahmed Abdal Dayem, Sebastian Kmiecik, Kyung Min Lim, Dong Sik Seo, Hyeong-Taek Kim, Polash Kumar Biswas, Minjae Do, Deok-Ho Kim, Ssang-Goo Cho
    Academic press:
    Journal of Advanced Research (rok: 2023, tom: 28, strony: S2090-1232), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.jare.2023.09.041 - link to the publication
  4. Fatty Acids Reverse the Supramolecular Chirality of Insulin Fibrils
    Authors:
    Aidan P Holman, Kimberly Quinn, Rakesh Kumar, Sebastian Kmiecik, Abid Ali, Dmitry Kurouski
    Academic press:
    The Journal of Physical Chemistry Letters (rok: 2023, tom: 14, 30, strony: 6935–6939), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.jpclett.3c01527 - link to the publication