Projects funded by the NCN


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50 projects found matching your search criteria :

  1. Structure-based dynamical models of large and complex biomolecular systems

    Call: OPUS 8 , Panel: ST3

    Principal investigator: prof. Marek Cieplak

    Instytut Fizyki PAN

  2. Molecular basis of amyloidogenesis - structure of conformational dynamics slected complexes of human prion protein PrPc ...

    Call: OPUS 8 , Panel: ST4

    Principal investigator: prof. Maciej Kozak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

  3. Middle ear dynamics with smart prosthesis

    Call: OPUS 7 , Panel: ST8

    Principal investigator: dr hab. Rafał Rusinek

    Politechnika Lubelska, Wydział Mechaniczny

  4. Structural and biophysical characteristics of highly conserved zinc hook domain of Rad50 protein - Studies on stability ...

    Call: OPUS 7 , Panel: NZ1

    Principal investigator: dr hab. Artur Krężel

    Uniwersytet Wrocławski, Wydział Biotechnologii

  5. Structural and dynamic aspect of the electrostatic interaction in HIV-1 protease.

    Call: PRELUDIUM 7 , Panel: ST4

    Principal investigator: Prashant Kumar

    Uniwersytet Warszawski, Wydział Chemii

  6. Modeling realistic tear film structure including tear protein and analyzing its role in stability and biophysical proper...

    Call: PRELUDIUM 6 , Panel: ST7

    Principal investigator: Alicja Wizert

    Politechnika Wrocławska, Wydział Podstawowych Problemów Techniki

  7. Hydration effects in protein kinases

    Call: SONATA 6 , Panel: ST4

    Principal investigator: dr Piotr Setny

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  8. Protein stability in aqueous solutions of osmolytes studied through complementary theoretical and experimental approach

    Call: OPUS 6 , Panel: NZ1

    Principal investigator: prof. Janusz Stangret

    Politechnika Gdańska, Wydział Chemiczny

  9. An integrated approach to the prediction of the structures of proteins and protein complexes with the use of the coarse-...

    Call: HARMONIA 5 , Panel: ST4

    Principal investigator: prof. Józef Liwo

    Uniwersytet Gdański, Wydział Chemii

  10. Design, parametrization and implementation of potentials of amino acid side chain interactions in water for application ...

    Call: SONATA BIS 3 , Panel: ST4

    Principal investigator: dr hab. Mariusz Makowski

    Uniwersytet Gdański, Wydział Chemii

  11. Simulation of conformational changes related to the interdomain communication in the eukaryotic GlcN-6-P synthase by mea...

    Call: PRELUDIUM 5 , Panel: NZ2

    Principal investigator: Aleksandra Miszkiel

    Politechnika Gdańska, Wydział Chemiczny

  12. Dynamics of binding of heterochromatin protein 1 (HP1) and its significance for DNA replication.

    Call: OPUS 5 , Panel: NZ3

    Principal investigator: dr Tytus Bernas

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  13. Kinesin in motion relatively to tubulin - properties of solvation water and interactions between proteins

    Call: SONATA 5 , Panel: NZ1

    Principal investigator: dr Anna Kuffel

    Politechnika Gdańska, Wydział Chemiczny

  14. Virtual High Throughput Screening (vHTS) derivation of a cross-immunity model for the Influenza-A Virus Infections.

    Call: OPUS 5 , Panel: NZ2

    Principal investigator: dr hab. Dariusz Plewczyński

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  15. Structural studies based on low sequence similarity of G protein-coupled receptors activated by hormones and allosteric ...

    Call: SONATA 4 , Panel: NZ1

    Principal investigator: dr Dorota Latek

    Uniwersytet Warszawski, Wydział Chemii

  16. Structure and properties of protein layers: from biomolecules to a functional layer (a combined experimental and simulat...

    Call: OPUS 4 , Panel: ST5

    Principal investigator: dr hab. Barbara Jachimska

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  17. Structure and dynamics of protein chain at its folding temparature

    Call: PRELUDIUM 3 , Panel: ST4

    Principal investigator: Anna Hałabis

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  18. Synchrotron small angle X-ray scattering and TEM microscopy studies of Hsp90:Sgt1:Rar1 and Sgt1 TPR domain dimer complex...

    Call: PRELUDIUM 3 , Panel: ST3

    Principal investigator: Michał Taube

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

  19. Solution NMR investigations of human cystatin C - structure, dynamics and protein-ligand interactions.

    Call: PRELUDIUM 2 , Panel: ST4

    Principal investigator: Martyna Maszota-Zieleniak

    Uniwersytet Gdański, Wydział Chemii

  20. Exposing unseen passages - towards identification of functional transient tunnels in protein structures

    Call: PRELUDIUM BIS 5 , Panel: NZ2

    Principal investigator: dr hab. Jan Brezovský

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  21. Theoretical prediction, chemical synthesis and biological analysis of a novel class of HSPA5 inhibitors

    Call: OPUS 25 , Panel: ST4

    Principal investigator: prof. Arkadiusz Chworoś

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  22. Optimization of coarse-grained molecular dynamics simulations for tunnel exploration of large proteins with buried activ...

    Call: PRELUDIUM 22 , Panel: NZ2

    Principal investigator: Nishita Mandal

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  23. Decrypting the "sulfation code" of glycosaminoglycans for understanding their function in the extracellular matrix

    Call: OPUS 25 , Panel: ST4

    Principal investigator: dr hab. Sergey Samsonov

    Uniwersytet Gdański, Wydział Chemii

  24. The thylakoid soluble phosphoprotein 9 (TSP9) as a novel partner of plant cytochrome b6f - exploring dynamics of its int...

    Call: OPUS 24 , Panel: NZ1

    Principal investigator: prof. Artur Osyczka

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  25. Co-translational protein folding in the light of ribosome evolution

    Call: POLONEZ BIS 3 , Panel: NZ1

    Principal investigator: dr Tomasz Włodarski

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  26. Function, organization, dynamics, and evolution of hyperbranched receptor-binding protein systems in Klebsiella jumbo ph...

    Call: OPUS 24 (LAP) , Panel: NZ1

    Principal investigator: prof. Zuzanna Drulis-Kawa

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  27. Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap...

    Call: SONATA BIS 12 , Panel: ST4

    Principal investigator: dr Karolina Mikulska-Rumińska

    Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  28. Dynamics and evolution of specificity of TA complexes

    Call: POLONEZ BIS 2 , Panel: NZ1

    Principal investigator: dr Grzegorz Grabe

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  29. Data-assisted modeling of the ensemble structure of intrinsically disordered proteins and their assemblies

    Call: SHENG 2 , Panel: ST4

    Principal investigator: prof. Józef Liwo

    Uniwersytet Gdański, Wydział Chemii

  30. Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Paweł Siedlecki

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  31. Self-learning systems in the design of compounds modulating GPCR receptors activation.

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: dr hab. Dorota Latek

    Uniwersytet Warszawski, Wydział Chemii

  32. The influence of environment on biomolecular function, structure and interactions.

    Call: SONATA BIS 10 , Panel: ST4

    Principal investigator: dr hab. Piotr Setny

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  33. Quantifying evolutionary dynamics of tails in phages infecting bacteria of Klebsiella pneumoniae

    Call: OPUS 19 , Panel: NZ8

    Principal investigator: dr Rafał Mostowy

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  34. Computational studies of the disulfide-bond role in proteins.

    Call: SONATA 15 , Panel: ST4

    Principal investigator: dr Paweł Krupa

    Instytut Fizyki Polskiej Akademii Nauk

  35. Seeking for CB1 and CB2 receptor ligands among drugs, drug metabolites, and phytochemical compounds

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Adam Stasiulewicz

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  36. Computational study of protein folding and dimerization on the ribosome

    Call: OPUS 18 , Panel: ST4

    Principal investigator: prof. Mai Suan Li

    Instytut Fizyki Polskiej Akademii Nauk

  37. Molecular mechanisms, signal transduction and inhibition of PEBP1-15LOX protein complex triggering the ferroptotic cell ...

    Call: SONATA 15 , Panel: ST4

    Principal investigator: dr Karolina Mikulska-Rumińska

    Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  38. Novel methods for structural biology of large symmetric protein assemblies by solid-state Nuclear Magnetic Resonance (NM...

    Call: OPUS 17 , Panel: ST4

    Principal investigator: dr Jan Stanek

    Uniwersytet Warszawski, Wydział Chemii

  39. Computational insights into procathepsin maturation mediated by glycosaminoglycans.

    Call: PRELUDIUM 16 , Panel: ST4

    Principal investigator: Krzysztof Bojarski

    Uniwersytet Gdański, Wydział Chemii

  40. Modeling of glycosaminoglycan-induced formation of protein structure and enhancement of biologically relevant protein-li...

    Call: SONATA BIS 8 , Panel: ST4

    Principal investigator: dr Sergey Samsonov

    Uniwersytet Gdański, Wydział Chemii

  41. An integrated approach to modeling protein structure and dynamics based on the UNRES coarse-grained force field and bioi...

    Call: HARMONIA 9 , Panel: ST4

    Principal investigator: dr hab. Cezary Czaplewski

    Uniwersytet Gdański, Wydział Chemii

  42. Increasing global and local accuracy of the coarse-grained UNRES model of proteins and its extensions to simulating very...

    Call: OPUS 13 , Panel: ST4

    Principal investigator: prof. Józef Liwo

    Uniwersytet Gdański, Wydział Chemii

  43. Enabling routine and reliable analysis of transport tunnels in proteins

    Call: OPUS 13 , Panel: NZ1

    Principal investigator: dr Jan Brezovsky

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  44. Structural determinants of optical control of insulin and neuroligin release by photoactive protein ligands.

    Call: OPUS 12 , Panel: ST4

    Principal investigator: prof. Wiesław Nowak

    Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  45. Mechanism of substrate recognition and binding by gamma-secretase on the example of the amyloid precursor protein

    Call: PRELUDIUM 12 , Panel: ST4

    Principal investigator: Łukasz Nierzwicki

    Politechnika Gdańska, Wydział Chemiczny

  46. Structure and reactivity of proteins in the gas phase - a meeting between advanced mass spectrometry and molecular model...

    Call: HARMONIA 8 , Panel: ST4

    Principal investigator: dr Jarosław Panek

    Uniwersytet Wrocławski, Wydział Chemii

  47. Multiple functions of RFC protein complex in the architecture and dynamics of replication factories in cell nuclei

    Call: PRELUDIUM 11 , Panel: NZ3

    Principal investigator: Maciej Krupa

    Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

  48. Computational approaches to study protein-glycosaminoglycan interactions

    Call: POLONEZ 2 , Panel: ST4

    Principal investigator: dr Sergey Samsonov

    Uniwersytet Gdański, Wydział Chemii

  49. Dynamic changes of carp seminal proteins and their modifications upon sperm maturation, hormonal stimulation and storage...

    Call: OPUS 11 , Panel: NZ9

    Principal investigator: dr hab. Mariola Dietrich

    Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

  50. Memetic algorithms for the excited ligand diffusion in condensed biological matter

    Call: PRELUDIUM 10 , Panel: ST3

    Principal investigator: Jakub Rydzewski

    Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej