Projects funded by the NCN
"I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to improve pharmacological efficacy
2023/49/B/NZ7/03340
Keywords:
computer-aided drug design G protein-coupled receptors drug kinetics molecular dynamics machine learning compound residence time serotonin receptors opioid receptors
Descriptors:
- NZ2_7: Bioinformatics
- NZ7_14: Pharmacy, pharmacotherapy, pharmacology
- ST6_11: Machine learning, statistical data processing and applications using signal processing (e.g. speech, image, video)
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk
woj.
Principal investigator (from the host institution):
Number of co-investigators in the project: 6
Call: OPUS 25 - announced on 2023-03-16
Amount awarded: 1 661 823 PLN
Project start date (Y-m-d): 2024-11-28
Project end date (Y-m-d): 2028-11-27
Project duration:: 48 months (the same as in the proposal)
Project status: Pending project
Project description
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