Projects funded by the NCN

Cooperative involvement of serotonergic signaling and extracellular matrix in synaptic plasticity underlying the pathoge...

Call: HARMONIA 3 , Panel: NZ3

Principal investigator: dr hab. Jakub Włodarczyk

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Plasticity of glutamatergic synapses on dopamine neurons: the mechanism of habit formation.

Call: HARMONIA 3 , Panel: NZ4

Principal investigator: dr hab. Jan Rodriguez-Parkitna

Instytut Farmakologii PAN

UP9/LSU protein as a potential function modulator of selective autophagy receptor in plants

Call: PRELUDIUM 3 , Panel: NZ1

Principal investigator: Katarzyna Zientara-Rytter

Instytut Biochemii i Biofizyki PAN

WWOX tumour supressor gene - function characterisation in normal mammary and breast cancer cells

Call: OPUS 3 , Panel: NZ2

Principal investigator: prof. Andrzej Bednarek

Uniwersytet Medyczny w Łodzi, Wydział Nauk Biomedycznych i Kształcenia Podyplomowego

The molecular mechanism of Hecate-FSHbeta conjugate action on tumor cells expressing follicle stimulating hormone recept...

Call: OPUS 3 , Panel: NZ5

Principal investigator: dr Marcin Chruściel

Instytut Rozrodu Zwierząt i Badań Żywności PAN

The analysis of function of RCF-family proteins - potential gibberellin pathway membrane receptors in Arabidopsis with f...

Call: OPUS 1 , Panel: NZ1

Principal investigator: dr Tomasz Sarnowski

Instytut Biochemii i Biofizyki PAN

Development of ssDNA molecules recognizing cellular receptor of hyaluronic acid.

Call: PRELUDIUM 3 , Panel: NZ3

Principal investigator: Aleksandra Pęcak

UNIWERSYTET JAGIELLOŃSKI, Wydział Biochemii, Biofizyki i Biotechnologii

Polymers functionalized with molecular receptors.

Call: PRELUDIUM 3 , Panel: ST5

Principal investigator: dr Michał Cegłowski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Evolution and diversity of umami taste among carnivoran mammals in ecological, behavioural and phylogenetic contexts

Call: OPUS 3 , Panel: NZ8

Principal investigator: prof. Mieczysław Wolsan

Muzeum i Instytut Zoologii Polskiej Akademii Nauk

The role of polymorphisms and expressions of the receptors from the CD94/NKG2 family and the HLA-E molecule in etiopatho...

Call: PRELUDIUM 3 , Panel: NZ5

Principal investigator: Milena Iwaszko

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

Molecular characterization of Chd64 and FKBP39 proteins, key components of multiprotein complex mediating juvenile hormo...

Call: OPUS 3 , Panel: NZ1

Principal investigator: prof. Andrzej Ożyhar

Politechnika Wrocławska, Wydział Chemiczny

Searching for the molecular mechanisms of the therapeutic use of histamine signal and histamine receptors H1R, H2R and H...

Call: HARMONIA 2 , Panel: NZ6

Principal investigator: prof. Marek Jutel

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Lekarski

Search for new "drug-like" molecules designed as adenosine receptors ligands

Call: HARMONIA 2 , Panel: NZ4

Principal investigator: prof. Katarzyna Kieć-Kononowicz

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Studies on apoptosis and oxidative damage to biological molecules in tissue-specific and non-specific growth hormone rec...

Call: HARMONIA 2 , Panel: NZ4

Principal investigator: dr hab. Adam Gesing

Uniwersytet Medyczny w Łodzi, Wydział Lekarski z Oddziałem Stomatologicznym

Probing molecular recognition by mass spectrometry. A case study: Examination of properties of non-covalent complexes of...

Call: SONATA 2 , Panel: ST4

Principal investigator: dr Magdalena Zimnicka

Instytut Chemii Organicznej PAN

Role of the orexin - orexin receptors system in the biology of human prostate epithelial cells. Studies of cell lines of...

Call: PRELUDIUM 2 , Panel: NZ3

Principal investigator: Marta Szyszka

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

Structure-activity relationship of bifunctional peptides, agonists of opioid receptors and antagonists of neurokinin rec...

Call: PRELUDIUM 2 , Panel: ST5

Principal investigator: Jolanta Dyniewicz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Conjugated linoleic acid (CLA)-induced transcriptional activation of PPAR-an investigation of molecular machanisms of pu...

Call: OPUS 2 , Panel: NZ9

Principal investigator: prof. Teresa Leszczyńska

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Technologii Żywności

The role of the mGlu5-D2 heterodimeric receptor complexes in the extinction of drug seeking behavior associated with dep...

Call: SONATA 2 , Panel: NZ7

Principal investigator: dr Małgorzata Frankowska

Instytut Farmakologii Polskiej Akademii Nauk, Instytut Farmakologii Polskiej Akademii Nauk

The molecular basis of stress-induced anxiety and affective disorders

Call: OPUS 2 , Panel: NZ2

Principal investigator: dr Michał Korostyński

Instytut Farmakologii PAN

Dioscuri Center for Structural Dynamics of Receptors

Call: DIOSCURI 4 , Panel: NZ1

Principal investigator: Przemysław Nogły

Uniwersytet Jagielloński

Zn2+-dependent competition between CD4 and CD8α coreceprtor for Lck tyrosine kinase

Call: SONATA 19 , Panel: NZ1

Principal investigator: dr Anna Kocyła

Uniwersytet Wrocławski, Wydział Biotechnologii

Semaglutide and neurodevelopment: investigating risks arising from prenatal exposure to a widely popular drug for diabet...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Wnuk

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Deciphering the importance of the intracellular FGFR1 module for cell fate

Call: OPUS 26 , Panel: NZ1

Principal investigator: dr hab. Małgorzata Zakrzewska

Uniwersytet Wrocławski, Wydział Biotechnologii

Retro-inverso modification of zinc(II)–GLP-1 receptor agonist complexes – from bioinorganic chemistry to animal studies...

Call: OPUS 26 , Panel: ST5

Principal investigator: dr hab. Magdalena Rowińska-Żyrek

Uniwersytet Wrocławski, Wydział Chemii

First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Jadwiga Handzlik

Uniwersytet Jagielloński, Collegium Medicum

Regulation of clathrin-dependent endocytosis by mTOR kinase in neuronal development

Call: OPUS 2 , Panel: NZ3

Principal investigator: prof. Jacek Jaworski

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Proteolytic processing of adhesion G-protein coupled receptors through proteases

Call: WEAVE-UNISONO , Panel: NZ1

Principal investigator: dr Renata Mężyk-Kopeć

Uniwersytet Jagielloński

Study on novel sensing layers for determination of quorum sensing signal molecules

Call: SONATA BIS 13 , Panel: ST5

Principal investigator: dr hab. Kamila Sadowska

Instytut Biocybernetyki i Inżynierii Biomedycznej im. Macieja Nałęcza Polskiej Akademii Nauk

Crownphyrins - hybrids of crown ethers and porphyrins, constituting macrocyclic platforms for the construction of two- a...

Call: PRELUDIUM BIS 5 , Panel: ST4

Principal investigator: dr hab. Bartosz Szyszko

Uniwersytet Wrocławski, Wydział Chemii

The role of MCPIP1 in the regulation of innate immunity during infection

Call: OPUS 2 , Panel: NZ6

Principal investigator: dr hab. Joanna Kozieł

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Novel receptor materials for the construction of a bioelectronic nose for the rapid and efficient detection of lung canc...

Call: OPUS 25 , Panel: ST5

Principal investigator: prof. Wojciech Kamysz

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Molecular geometry – pre- and post-synthetically modified shape-persistent macrocycles of great chiroptical response, fo...

Call: OPUS 25 , Panel: ST5

Principal investigator: prof. Marcin Kwit

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Study of ligand binding and activation processes of formyl, opioid and cannabinoid G-protein-coupled receptors

Call: OPUS 2 , Panel: NZ1

Principal investigator: prof. Sławomir Filipek

Uniwersytet Warszawski, Wydział Chemii

Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Bernadeta Pietrzak-Wawrzyńska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Psychedelic-induced molecular changes in the brain

Call: SONATINA 7 , Panel: NZ2

Principal investigator: dr Dominik Cysewski

Uniwersytet Medyczny w Białymstoku

EBI2 receptor as a new myelin repair therapy in multiple sclerosis.

Call: SONATA 18 , Panel: NZ3

Principal investigator: dr Aleksandra Rutkowska

Gdański Uniwersytet Medyczny, Centrum Chorób Mózgu

Function, organization, dynamics, and evolution of hyperbranched receptor-binding protein systems in Klebsiella jumbo ph...

Call: OPUS 24 (LAP) , Panel: NZ1

Principal investigator: prof. Zuzanna Drulis-Kawa

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

In vitro and in vivo investigations of the radiometals influence on the ability of CCK2R receptors imaging by the radiol...

Call: OPUS 2 , Panel: ST5

Principal investigator: dr hab. Renata Mikołajczak

Narodowe Centrum Badań Jądrowych

The role of lipoproteins and lipoprotein receptors in mediating the effects of childhood trauma on the brain and the ger...

Call: PRELUDIUM 21 , Panel: NZ3

Principal investigator: Weronika Tomaszewska

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Molecular implications of gut microbiota disorders in the context of the immune system functioning in patients with prim...

Call: OPUS 23 , Panel: NZ6

Principal investigator: prof. Ewelina Grywalska

Uniwersytet Medyczny w Lublinie

Proinsulin C-peptide and G protein-coupled receptor 146 (GPR146) – clinical investigation of the impact of their signall...

Call: PRELUDIUM 21 , Panel: NZ4

Principal investigator: Aleksandra Ryk

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Allosteric and allosteric-orthosteric bitopic ligands of histamine receptor H4 as a way to increase selectivity and bias...

Call: OPUS 23 , Panel: NZ7

Principal investigator: prof. Sławomir Filipek

Uniwersytet Warszawski, Wydział Chemii

Highly-internalizing intrinsically fluorescent oligomeric cytotoxic conjugate targeting breast cancer cells overproducin...

Call: PRELUDIUM 21 , Panel: NZ1

Principal investigator: dr Natalia Porębska

Uniwersytet Wrocławski, Wydział Biotechnologii

Use of comparative oncology approach to dissect the PD-1 intrinsic signalling in osteosarcoma. Can dog be the key for ne...

Call: PRELUDIUM 21 , Panel: NZ1

Principal investigator: Katarzyna Dziubek

Uniwersytet Gdański, Międzynarodowe Centrum Badań nad Szczepionkami Przeciwnowotworowymi

Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Karolina Przepiórska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Magdalena Białoń

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

mRNA export regulation during global poly(A)RNA nuclear retention in plant cells.

Call: PRELUDIUM 21 , Panel: NZ3

Principal investigator: Karolina Majewska

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Nauk Biologicznych i Weterynaryjnych

Peptide receptor complexes for auxin canalization and regeneration in Arabidopsis.

Call: OPUS 22 (LAP) , Panel: NZ1

Principal investigator: dr Ewa Mazur

Uniwersytet Śląski w Katowicach, Wydział Nauk Przyrodniczych