Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Molecular analysis of clear cell renal cell carcinoma progression in the context of the search for predictive factors prior to treatment

2013/09/D/NZ5/00249

Keywords:

tumor progression MET receptor CXCR4 receptor molecular analysis ephitelial to mesenchymal transition

Descriptors:

  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Katarzyna Miękus 

Number of co-investigators in the project: 6

Call: SONATA 5 - announced on 2013-03-15

Amount awarded: 754 120 PLN

Project start date (Y-m-d): 2014-03-28

Project end date (Y-m-d): 2018-03-27

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. aparatura do metody western blot (10 000 PLN)
  2. drukarka (500 PLN)
  3. komputer przenośny (5 000 PLN)
  4. komputer stacjonarny (2 861 PLN)
  5. wirówka (25 000 PLN)
  6. homogenizator tkanek (10 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. MCPIP1 downregulation in clear cell renal cell carcinoma promotes vascularization and metastatic progression
    Authors:
    Marona P, Górka J, Mazurek Z, Wilk W, Rys J, Majka M, Jura J, Miekus K
    Academic press:
    Cancer Research (rok: 2017, tom: 77(18), strony: 4905-4920), Wydawca: AACR journals
    Status:
    Published
    DOI:
    10.1158/0008-5472.CAN-16-3190 - link to the publication
  2. The Met tyrosine kinase receptor as a therapeutic target and a potential cancer stem cell factor responsible for therapy resistance
    Authors:
    Miekus K
    Academic press:
    Oncology Reports (rok: 2017, tom: 37 (2), strony: 647-656), Wydawca: Spandisos Publications
    Status:
    Published
    DOI:
    10.3892/or.2016.5297 - link to the publication
  3. RNAza MCPIP1 jako istotny regulator wewnątrzkomórkowej puli RNA
    Authors:
    Pydyn N, Miękus K, Kotlinowski J
    Academic press:
    Postępy Higieny i Medycyny Doświadczalnej (rok: 2018, tom: 72, strony: 0,0479166666666667), Wydawca: Czasopismo Instytutu Immunologii i Terapii Doświadczalnej Polskiej Akademii Nauk im. Ludwika Hirszfelda
    Status:
    Published
    DOI:
    10.5604/01.3001.0011.8255 - link to the publication

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