Projects funded by the NCN

Blood plasma microRNA profile as a basis for detecting Alzheimer's disease and dementia risk in pre-symptomatic individu...

Call: OPUS 24 , Panel: NZ7

Principal investigator: prof. Urszula Wojda

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Unveiling the molecular signature underlying resistance to CD19 CAR-T therapy in malignant cells.

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Marta Krawczyk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Molecular profiling of soft tissue sarcomas in tumor and peripheral blood in terms of response to treatment and early de...

Call: OPUS 25 , Panel: NZ5

Principal investigator: prof. Piotr Rutkowski

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy

"I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr...

Call: OPUS 25 , Panel: NZ7

Principal investigator: dr hab. Sabina Podlewska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Anticancer potential of TMPyP4 porphyrin in breast cancer photodynamic therapy and evaluation of the treatment safety

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Błażej Rubiś

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Compounds modulating function of telomeric proteins TRF1 and TRF2

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Maciej Bagiński

Politechnika Gdańska, Wydział Chemiczny

Prioritizing diagnostics and therapeutics of human prion diseases through integrative omics

Call: JPND Call 2023 , Panel: NZ2

Principal investigator: prof. Beata Sikorska

Uniwersytet Medyczny w Łodzi

Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Magdalena Wujak

Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

The role of oxidative stress, inflammation, disorders of purine metabolism, urea cycle and angiogenesis at the molecular...

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Paulina Wigner-Jeziorska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Tumor viscoelasticity as a central player in glioblastoma treatment - towards mechanopharmacology

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Pogoda

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego Polskiej Akademii Nauk

The impact of physical activity on the gut-brain axis molecular adaptation to chronic stress

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Julia Morys

Akademia Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach

Innovative Small Molecule Inhibitors Targeting LAG-3 and MHCII Complex for Tumour Immunotherapy

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr Jacek Plewka

Uniwersytet Jagielloński w Krakowie

AI-based model for fast and label-free identification of BAALC overexpression in acute myeloid leukemia cells

Call: PRELUDIUM 23 , Panel: NZ1

Principal investigator: Paulina Laskowska

Instytut Hematologii i Transfuzjologii

Effect of Urolithin A on gut microbiota and intestinal integrity contributing to neuroprotective effects in a model of P...

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Olga Wojciechowska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Novel human topoisomerase II inhibitors as anticancer agents

Call: PRELUDIUM 15 , Panel: NZ7

Principal investigator: dr Barbara Kaproń

Uniwersytet Medyczny w Lublinie, Wydział Nauk o Zdrowiu

Comparative analysis of intrinsic molecular subtypes as defined by PAM50 of circulating, primary and metastatic tumour c...

Call: PRELUDIUM 15 , Panel: NZ4

Principal investigator: Marcin Braun

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Dissecting of the novel mechanisms in multi-drug resistance associated with vault's proteins and translation initiation ...

Call: SONATA BIS 8 , Panel: NZ7

Principal investigator: dr hab. Witold Szaflarski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

Specific interactions of new antitumor unsymmetrical bisacridines, UAs, with DNA and ABC proteins and their potential to...

Call: OPUS 17 , Panel: NZ7

Principal investigator: prof. Zofia Mazerska

Politechnika Gdańska

Identyfication of changes in expression profile of mRNAs and proteins in blood platelets, as potential molecular markers...

Call: PRELUDIUM 17 , Panel: NZ7

Principal investigator: dr Rafał Piotr Szelenberger

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

The use of olaparib and ATR / CHK1 kinase inhibitors as a targeted anti-cancer therapy based on synthetic lethality

Call: SONATA BIS 9 , Panel: NZ7

Principal investigator: dr hab. Aneta Katarzyna Rogalska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Molecular mechanisms of interplay between RORγ/RORγT receptors and cyclin-dependent kinase inhibitor (AT7519). Analysis ...

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Kaja Urszula Karaś

Instytut Biologii Medycznej Polskiej Akademii Nauk

Seeking for CB1 and CB2 receptor ligands among drugs, drug metabolites, and phytochemical compounds

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Adam Stasiulewicz

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Identification of molecular mechanism of Escherichia coli response to antimicrobial blue light inactivation by genome-wi...

Call: SONATINA 4 , Panel: NZ7

Principal investigator: dr Aleksandra Małgorzata Rapacka-Zdończyk

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Influence of modified maternal diet on the phenotype of offspring: behavioral and molecular correlations

Call: ETIUDA 8 , Panel: NZ7

Principal investigator: Kinga Gawlińska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer...

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Anna Marta Pasieka

Uniwersytet Jagielloński, Collegium Medicum

Genomic profiling of circulating biomarkers and matched primary tumors from breast cancer patients

Call: OPUS 20 (LAP) , Panel: NZ5

Principal investigator: dr Aleksandra Markiewicz

Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Epidemiology and rapid spread of antimicrobial resistance amongAcinetobacter spp. strains in hospital units - analysis u...

Call: PRELUDIUM BIS 2 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Chmielarczyk

Uniwersytet Jagielloński, Collegium Medicum

Molecular mechanism of the protective effect of swimming training on skeletal muscle atrophy and the course of amyotroph...

Call: OPUS 20 , Panel: NZ7

Principal investigator: prof. Wiesław Ziółkowski

Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Instytutem Medycyny Morskiej i Tropikalnej