Projects funded by the NCN

The influence of bone marrow microenvironment on the regulation of BRCA1 mRNA translation in leukemia cells; role in the...

Call: SONATA 8 , Panel: NZ3

Principal investigator: dr Paulina Podszywałow-Bartnicka

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

The role of the 5' non-coding regions of p53 mRNA transcripts, which are synthesized from various transcription promoter...

Call: OPUS 5 , Panel: NZ1

Principal investigator: prof. Jerzy Ciesiołka

Instytut Chemii Bioorganicznej PAN

Designing mRNA transcripts resistant to enzymatic cap hydrolysis applicable for anti-cancer vaccines; multiplexed bioche...

Call: MAESTRO 4 , Panel: NZ1

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Centrum Nowych Technologii

Members of eIF4E protein family, their affinities towards 5' mRNA cap and protein binding partners: an interdisciplinary...

Call: OPUS 4 , Panel: NZ1

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Wydział Fizyki

An effect of hypothalamic GnRH neurons activity on SF-1, beta-catenin and Dax 1 genes trancription and translation activ...

Call: SONATA 3 , Panel: NZ9

Principal investigator: dr Marlena Zielińska-Górska

Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego PAN

Synthesis of mononucleotide N2,N2,7-trimethylguanosine cap analogues as translation inhibitors in Ascaris suum

Call: PRELUDIUM 3 , Panel: ST5

Principal investigator: dr Karolina Piecyk

Uniwersytet Warszawski, Wydział Chemii

Conjugates of cap analogs with nanomaterials and biomolecules with potential applications in pharmacology or diagnostics

Call: SONATA 1 , Panel: ST5

Principal investigator: dr Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

Nuclear mRNA retention and delayed translation as a novel mechanism of post-transcriptional mRNA regulation in plants

Call: PRELUDIUM BIS 5 , Panel: NZ3

Principal investigator: dr hab. Dariusz Smoliński

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Nauk Biologicznych i Weterynaryjnych

Linkage between Maf1-mediated control of tRNA transcription and mRNA translation in Saccharomyces cerevisiae yeast

Call: PRELUDIUM 21 , Panel: NZ1

Principal investigator: Alicja Armatowska

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Synthesis and structural/biophysical studies of model mRNA/mt-tRNA oligomers to evaluate the role of modified nucleoside...

Call: OPUS 22 , Panel: ST4

Principal investigator: dr hab. Grażyna Leszczyńska

Politechnika Łódzka

Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRN...

Call: SONATA 16 , Panel: ST4

Principal investigator: dr Dorota Gudanis

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

FAST interactions in cell death regulation

Call: PRELUDIUM 19 , Panel: NZ1

Principal investigator: Daria Dawidziak

Uniwersytet Warszawski, Wydział Chemii

Ribozyme-based potential antibacterial strategy

Call: PRELUDIUM 19 , Panel: NZ1

Principal investigator: Joanna Miszkiewicz

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

mRNA 5' end methylation status: towards deeper understanding of biological role and identification of synthetic mimics

Call: OPUS 17 , Panel: ST4

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Designing modified mRNAs as vaccines and therapeutic protein carriers. Studies on their immunogenicity in the context of...

Call: OPUS 17 , Panel: NZ1

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Gold and silver nanoparticles as carriers for delivery of 5' end mRNA cap analogues with potential therapeutical applica...

Call: OPUS 16 , Panel: ST5

Principal investigator: dr hab. Marzena Jankowska-Anyszka

Uniwersytet Warszawski, Wydział Chemii

Mechanisms of human gene expression regulation by uridilation

Call: SONATA 13 , Panel: NZ1

Principal investigator: dr hab. Zbigniew Warkocki

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Bacterial chaperone protein Hfq in noncoding RNA-dependent translation regulation

Call: OPUS 1 , Panel: NZ1

Principal investigator: dr hab. Mikołaj Olejniczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

How RNA structure governs messenger RNA function? Exploring structural and functional aspects essential for synthesis of...

Call: SONATA 12 , Panel: NZ1

Principal investigator: dr Leszek Błaszczyk

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

The role of protein factors that bind to the 5' non-coding region of human p53 mRNA in regulation of p53 expression at t...

Call: OPUS 11 , Panel: NZ1

Principal investigator: prof. Jerzy Ciesiołka

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk