Projects funded by the NCN
Ribozyme-based potential antibacterial strategy
2020/37/N/NZ1/03987
Keywords:
ribozymes hammerhead ribozyme catalytic RNA mRNA hydrolysis inhibition of translation bacteria E. coli antibiotics
Descriptors:
- NZ1_002:
- NZ1_009:
- NZ1_001:
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 19 - announced on 2020-03-16
Amount awarded: 139 644 PLN
Project start date (Y-m-d): 2021-02-10
Project end date (Y-m-d): 2023-12-09
Project duration:: 34 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Hammerhead ribozymes directed against mRNA of an essential gene inhibit Escherichia coli growth and enhance tetracycline efficacyAuthors:Joanna Miszkiewicz-Golec, Ksenia Maximova, Maciej Łukaszewicz, Dariusz Bartosik, Edward Darżynkiewicz, Joanna TrylskaAcademic press:Frontiers in Microbiology (rok: 2025, tom: 16, strony: 1663476), Wydawca: Frontiers Media S.A.Status:PublishedDOI:10.3389/fmicb.2025.1663476 - link to the publication