Projects funded by the NCN

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237 projects found matching your search criteria :

  1. Two sides of the same coin: leveraging order and disorder at the molecular level for the design and preparation of advan...

    Call: SONATA BIS 15 , Panel: ST5

    Principal investigator: dr Adam Paweł Gorczyński

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  2. Functional nanomaterials based on drug–lipid–ligands as targeted delivery systems for anticancer agents in lung adenocar...

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Piotr Paweł Szyk

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  3. Non-noble metal complexes bearing NHC ligands from renewable feedstocks as catalysts for sustainable synthesis of functi...

    Call: OPUS 29 , Panel: ST5

    Principal investigator: dr hab. Patrycja Karolina Żak

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  4. Design and Pharmacological Evaluation of Marine Alkaloid-Inspired 5-HT2A Receptor Ligands

    Call: PRELUDIUM 24 , Panel: NZ1

    Principal investigator: Szymon Kazimierz Kordylewski

    Instytut Farmakologii PAN

  5. The influence of beta2-receptor N-terminal polymorphismsadrenergic on its functionality, interactions withdrugs and the ...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr hab. Anita Elżbieta Płazińska

    Uniwersytet Medyczny w Lublinie

  6. A new concept of inhibiting the progression of Alzheimer's disease based on the modification of the blood-brain barrier ...

    Call: OPUS 28 , Panel: NZ4

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  7. Synthesis of ruthenium complexes with CAAC ligands, application in metathesis reactions

    Call: SONATA 20 , Panel: ST4

    Principal investigator: dr Adrian Sytniczuk

    Uniwersytet Warszawski

  8. Acyclic aminocarbenes and acyclic aminooxycarbenes as useful ligands for ruthenium complexes

    Call: OPUS 28 , Panel: ST4

    Principal investigator: dr hab. Anna Sylwia Kajetanowicz

    Uniwersytet Warszawski

  9. L-SWITCH: towards tailor-made molecular switches for specific applications – understanding of transition-metal coordinat...

    Call: OPUS 28 , Panel: ST4

    Principal investigator: dr hab. Katarzyna Natalia Jarzembska

    Uniwersytet Warszawski

  10. Implementation of Sustainable Sustainable Chemical Synthesis: Harnessing the Power of 3d-Electron Metal Compounds

    Call: SONATA BIS 14 , Panel: ST4

    Principal investigator: dr hab. Krzysztof Kuciński

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  11. Dual Se-containing 5-HT1A and 5-HT7 biased agonists activating sigma-1 receptor as a hope of finding fast-acting antidep...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Karolina Anna Pytka

    Uniwersytet Jagielloński

  12. Cyclic triel carbenoids as auxiliary ligands for ruthenium-based olefin metathesis catalysts

    Call: PRELUDIUM 23 , Panel: ST4

    Principal investigator: Tymoteusz Marek Basak

    Uniwersytet Warszawski

  13. Cobalt and Iron Complexes With Aminophosphine Ligands: Catalysts Design for Organic and Organometallic Synthesis

    Call: SONATINA 8 , Panel: ST4

    Principal investigator: dr Hanna Maria Stachowiak-Dłużyńska

    Fundacja Uniwersytetu im. Adama Mickiewicza

  14. Deciphering the promiscuous bioinorganic chemistry of putative copper transporters in bacteria

    Call: SONATA 19 , Panel: ST5

    Principal investigator: dr Aleksandra Anna Hecel-Czaplicka

    Uniwersytet Wrocławski, Wydział Chemii

  15. Insights in the phenylpropanoid transport in model legume plant Medicago truncatula

    Call: SONATA 19 , Panel: NZ9

    Principal investigator: dr Wanda Ada Biała-Leonhard

    Instytut Chemii Bioorganicznej PAN

  16. Playing with Carbene Ligand Rigidity to Control Olefin Metathesis Stability, Productivity and Selectivity

    Call: OPUS 26 , Panel: ST4

    Principal investigator: prof. Karol Lesław Grela

    Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

  17. Crownphyrins - hybrids of crown ethers and porphyrins, constituting macrocyclic platforms for the construction of two- a...

    Call: PRELUDIUM BIS 5 , Panel: ST4

    Principal investigator: dr hab. Bartosz Jakub Szyszko

    Uniwersytet Wrocławski, Wydział Chemii

  18. "I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Sabina Marta Podlewska

    Instytut Farmakologii PAN

  19. Optimization of coarse-grained molecular dynamics simulations for tunnel exploration of large proteins with buried activ...

    Call: PRELUDIUM 22 , Panel: NZ2

    Principal investigator: Nishita Mandal

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  20. New applications of non-conventional nonempirical methodologies for the analysis of catalytic and inhibitory properties ...

    Call: OPUS 25 , Panel: ST4

    Principal investigator: dr Edyta Dyguda-Kazimierowicz

    Politechnika Wrocławska

  21. Psychedelic-induced molecular changes in the brain

    Call: SONATINA 7 , Panel: NZ2

    Principal investigator: dr Dominik Łukasz Cysewski

    Uniwersytet Medyczny w Białymstoku

  22. Development of novel anti-cancer immunotherapy against mesothelioma comprising of oncolytic adenovirus vectors armed wit...

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Łukasz Kuryk

    Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny (NIZP - PZH)

  23. Palladium-catalyzed cascades for the rapid and enantioselective construction of polycyclic scaffolds of alkaloids and ps...

    Call: OPUS 24 , Panel: ST4

    Principal investigator: dr hab. Rafał Antoni Loska

    Instytut Chemii Organicznej Polska Akademia Nauk

  24. Thermodynamic contribution of halogen bonds in protein-ligand systems. Design, synthesis, and thermodynamic studies of m...

    Call: PRELUDIUM 21 , Panel: ST4

    Principal investigator: dr Sławomir Jan Kasperowicz

    Instytut Biochemii i Biofizyki PAN

  25. Metallocarbaporphyrinoids as ligands in monomeric and oligomeric complexes. Synthesis, interactions, and catalysis.

    Call: OPUS 23 , Panel: ST4

    Principal investigator: prof. Piotr Jan Chmielewski

    Uniwersytet Wrocławski, Wydział Chemii

  26. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii PAN

  27. Crystallographic analysis of RNA-ligand complexes. Towards rational design oflead compounds for development of therapies...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Ludmiła Kiliszek

    Instytut Chemii Bioorganicznej PAN

  28. Allosteric and allosteric-orthosteric bitopic ligands of histamine receptor H4 as a way to increase selectivity and bias...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Sławomir Hubert Filipek

    Uniwersytet Warszawski, Wydział Chemii

  29. Metallosupramolecular architectures based on flexidentate pyridyl-β-diketonate ligands - synthesis, properties and catal...

    Call: PRELUDIUM 21 , Panel: ST4

    Principal investigator: Gracjan Piotr Kurpik

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  30. Novel tricyclic glycomimetics as DC-SIGN receptor ligands.

    Call: OPUS 22 , Panel: ST4

    Principal investigator: dr Mykhaylo Potopnyk

    Instytut Chemii Organicznej Polska Akademia Nauk

  31. Development of the knowledge on the role of GPR18 ligands as a microglia-targeted strategy in the regulation of neuroinf...

    Call: SONATA 17 , Panel: NZ3

    Principal investigator: dr Ewelina Barbara Honkisz-Orzechowska

    Uniwersytet Jagielloński, Collegium Medicum

  32. Targeting cell surface proteoglycans with high affinity multimeric ligands and their cytotoxic conjugates – towards prec...

    Call: OPUS 22 , Panel: NZ1

    Principal investigator: dr hab. Łukasz Opaliński

    Uniwersytet Wrocławski, Wydział Biotechnologii

  33. Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Dorota Justyna Łażewska

    Uniwersytet Jagielloński, Collegium Medicum

  34. Research of multifunctional compounds targeting neuroinflammation and cholinergic deficit in Alzheimer's disease

    Call: OPUS 22 (LAP) , Panel: NZ7

    Principal investigator: prof. Kinga Aleksandra Sałat

    Uniwersytet Jagielloński, Collegium Medicum

  35. Reversible modulation of G-quadruplex functions using photoresponsive ligands - in vitro and cellular studies

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Marta Maria Dudek

    Politechnika Wrocławska

  36. The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Maria Kucwaj-Brysz

    Uniwersytet Jagielloński, Collegium Medicum

  37. True Bioisosteres - Structural and Thermodynamic Classification of Molecular Fragments for Ligand Design

    Call: SONATA BIS 11 , Panel: ST4

    Principal investigator: dr Maura Dagmara Malińska

    Uniwersytet Warszawski, Wydział Chemii

  38. Combating addiction by targeting α3β4*-nicotinic acetylcholine receptors

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Ákos Nemecz

    Uniwersytet Mikołaja Kopernika, Wydział Nauk Biologicznych i Weterynaryjnych

  39. Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec...

    Call: OPUS 21 , Panel: NZ1

    Principal investigator: prof. Elżbieta Beata Kierzek

    Instytut Chemii Bioorganicznej PAN

  40. First-in-class dual biased agonists of serotonin 5-HT1A and dopamine D2 receptors – an innovative approach in the search...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Marcin Roman Kołaczkowski

    Uniwersytet Jagielloński, Collegium Medicum

  41. Advanced coordination materials designed on the basis of functional silsesquioxanes

    Call: OPUS 21 , Panel: ST5

    Principal investigator: dr hab. Beata Dudziec

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  42. Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Paweł Aleksander Siedlecki

    Instytut Biochemii i Biofizyki PAN

  43. AXL receptor signaling in cancer cell growth and drug resistance

    Call: OPUS 20 , Panel: NZ3

    Principal investigator: prof. Marta Elżbieta Miączyńska

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  44. Photodynamics of metal complexes with 2,6-bis(thiazol-2-yl)pyridine derivatives functionalized by aryls and N-donors as ...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Anna Maria Maroń

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

  45. Multifunctional character of copper(II) macrocyclic complexes – utilization in atom transfer radical polymerization (ATR...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Adam Paweł Gorczyński

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  46. The new methodology for better understanding of ligand-RNA interactions.

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: dr Filip Artur Stefaniak

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  47. Silsesquioxanes as Multifunctional Ligands in Coordination Chemistry and Nano-Building Blocks for Hybrid Materials

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Łukasz John

    Uniwersytet Wrocławski, Wydział Chemii

  48. New therapies of opioid use disorder

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr Wojciech Barnaba Solecki

    Uniwersytet Jagielloński, Wydział Zarządzania i Komunikacji Społecznej

  49. Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRN...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Dorota Gudanis-Sobocińska

    Instytut Chemii Bioorganicznej PAN

  50. Input of the structure of influenza A virus RNA on regulation of virus proliferation. High throughput screening of small...

    Call: OPUS 20 , Panel: NZ1

    Principal investigator: prof. Elżbieta Beata Kierzek

    Instytut Chemii Bioorganicznej PAN

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