Projects funded by the NCN

Tumor viscoelasticity as a central player in glioblastoma treatment - towards mechanopharmacology

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Pogoda

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego Polskiej Akademii Nauk

New biomimetic 3D materials for potential use in advanced therapies of bone tissue diseases - 3D BioBone

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Joanna Kolmas

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Is there an escape from antibioticresistant ESKAPE pathogens present in wastewater - the importance of last-chance antib...

Call: SONATA 19 , Panel: NZ9

Principal investigator: dr Katarzyna Grudlewska-Buda

Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Magdalena Wujak

Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

PROteolysis TArgeting Chimeras (PROTACs) intended to knock down excessive amyloidogenic proteins, human islet amyloid po...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Elżbieta Jankowska

Uniwersytet Gdański, Wydział Chemii

Synthesis and application of new mixed-mode materials to study the metabolism of drugs used in Poland for the treatment ...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Sylwia Studzińska

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Chemii

Bacterial membrane carriers targeting tumor-associated microbes for advanced cancer therapy

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Monika Kluzek

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Functional and structural analysis of anticancer drugs as protein biosynthesis inhibitors

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Witold Szaflarski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

A new generation of scaffolds based on curdlan and whey protein isolate obtained by electrospinning for the treatment of...

Call: SONATA 19 , Panel: NZ7

Principal investigator: dr Katarzyna Klimek

Uniwersytet Medyczny w Lublinie

Exploring kinase hyperactivation as an innovative approach for chemo-immunotherapy for B cell acute lymphoblastic leukem...

Call: PRELUDIUM BIS 5 , Panel: NZ7

Principal investigator: dr hab. Małgorzata Firczuk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Compounds modulating function of telomeric proteins TRF1 and TRF2

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Maciej Bagiński

Politechnika Gdańska, Wydział Chemiczny

Curdlan-based biomaterial as a nanostructure carrier for controlled and targeted drug delivery in the treatment of deep ...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Aleksandra Nurzyńska

Uniwersytet Medyczny w Lublinie

Anticancer potential of TMPyP4 porphyrin in breast cancer photodynamic therapy and evaluation of the treatment safety

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Błażej Rubiś

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Synergy of strength and plasticity as an effect of perspective heat treatment of the latest generation medium-Mn steels ...

Call: PRELUDIUM 22 , Panel: ST11

Principal investigator: Adam Skowronek

Politechnika Śląska, Wydział Mechaniczny Technologiczny

Polarized Raman spectroscopy and diffraction studies of hydrated minerals with layered and microporous structures: metho...

Call: PRELUDIUM 22 , Panel: ST10

Principal investigator: Katarzyna Skrzyńska

Uniwersytet Śląski w Katowicach, Wydział Nauk Przyrodniczych

Amorphous Senolytics: A Breakthrough Approach in Senescence Modulation and Age-Related Disease Treatment

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Szymon Sip

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Targeting the serotonin 5-HT7 receptor in a search for new strategies of mental disorders treatment

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Patryk Pyka

Uniwersytet Jagielloński, Collegium Medicum

Chiral hybrids of quinones and quinols with double anticancer and antimicrobial activity against drug-resistant pathogen...

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Ryszard Ostaszewski

Instytut Chemii Organicznej Polskiej Akademii Nauk

The Role of the Mitochondrial Unfolded Protein Response (UPRmt) in Endothelial Function: a Possible Novel Target for the...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Sylwester Mosiołek

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Design, Synthesis and Characterization of Functionalized 1,2,4-Trioxanes/Trioxepanes for Antimalarial and Anticancer Use

Call: SONATINA 7 , Panel: NZ7

Principal investigator: dr Mohit Tiwari

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Novel high entropy alloys of FeCoNiXY and CoFeCrXY (X = Ta, B, Y = Al, Ti) with excellent soft magnetic and mechanical p...

Call: OPUS 24 , Panel: ST8

Principal investigator: dr hab. Wojciech Maziarz

Instytut Metalurgii i Inżynierii Materiałowej im. Aleksandra Krupkowskiego Polskiej Akademii Nauk

Effect of the chronic treatment with lamotrigine on changes in expression of genes related to seizure processes in the s...

Call: PRELUDIUM BIS 4 , Panel: NZ7

Principal investigator: prof. Kinga Borowicz-Reutt

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Evaluation of anti-neoplastic activity of LAB-derived postbiotics as a potential tool to support standard chemotherapy i...

Call: PRELUDIUM BIS 4 , Panel: NZ7

Principal investigator: prof. Janusz Szemraj

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

Precise molecular characterization of circulating tumour cells in patients with triple negative breast cancer using high...

Call: OPUS 24 , Panel: NZ7

Principal investigator: prof. Stefano Volinia

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Targeted poloxamer micelles with selected drugs as a strategy for overcoming the mechanisms of multidrug resistance in p...

Call: PRELUDIUM BIS 4 , Panel: NZ7

Principal investigator: prof. Tomasz Gośliński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Identification of placental genes and proteins associated with retention of fetal membranes, and assessment of serum lev...

Call: PRELUDIUM BIS 4 , Panel: NZ5

Principal investigator: dr hab. Anna Rapacz-Leonard

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Medycyny Weterynaryjnej

The advanced novel materials for effective bleeding and antimicrobial control in TCCC (Tactical Combat Casualty Care) an...

Call: SONATA 18 , Panel: NZ7

Principal investigator: dr Dorota Chełminiak-Dudkiewicz

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Chemii

The effect of maternal treatment with metformin in pregnancy and lactation on programming metabolic adverse conditions i...

Call: SONATA BIS 12 , Panel: NZ7

Principal investigator: dr hab. Monika Słupecka-Ziemilska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Modifiers of Muscleblind-like genes expression in health and disease.

Call: SONATA BIS 12 , Panel: NZ5

Principal investigator: dr hab. Ewa Stępniak-Konieczna

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

A smart stride for cancer: synergistic effect of co-delivery chemo- andphototherapeutic agents using magneto-fluorescent...

Call: POLONEZ BIS 2 , Panel: NZ7

Principal investigator: dr Prachi Ghoderao

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Flexible, stretchable and antibacterial curdlan-tannin dressing for the prevention and treatment of infected wounds - in...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Anna Michalicha

Uniwersytet Medyczny w Lublinie

Brain cytochrome P450 as a new target for the treatment of neurological and psychiatric diseases. Studies with human neu...

Call: OPUS 23 , Panel: NZ7

Principal investigator: prof. Władysława Daniel

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Histone demethylase inhibitors as chemosensitivity modulators in the treatment of head and neck squamous cell carcinoma

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Dawid Dorna

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Smart tissue engineering to change the paradigm of diabetes treatment

Call: OPUS 23 , Panel: NZ7

Principal investigator: dr Anna Czarna

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Bionanoparticles with a molecular targeting device as a weapon for breast cancer

Call: OPUS 23 , Panel: NZ7

Principal investigator: prof. Sylwia Rodziewicz-Motowidło

Uniwersytet Gdański, Wydział Chemii

The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

Call: OPUS 23 , Panel: NZ7

Principal investigator: dr Katarzyna Szczepańska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Partial agonists of alpha-2 adrenoceptors as new perspective of the effective and safe in reducting body weight and obes...

Call: OPUS 2 , Panel: NZ7

Principal investigator: dr Magdalena Dudek

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

The allostatic load concept as an attempt to understand biological and psychopathological consequences of the refugee cr...

Call: PRELUDIUM 21 , Panel: NZ5

Principal investigator: Julian Maciaszek

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Lekarski

New positive allosteric modulators of EAAT2 glutamate transporter as candidates for treatment of neurological and psychi...

Call: OPUS 23 , Panel: NZ7

Principal investigator: prof. Krzysztof Kamiński

Uniwersytet Jagielloński, Collegium Medicum

Effects of activation of cholinergic, noradrenergic, and serotonergic systems on respiratory impairment in Alzheimer's d...

Call: OPUS 23 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Kaczyńska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Two-component preparations in the treatment of infections caused by pathogenic microorganisms

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Katarzyna Szałapata

Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

'Mitotherapy as a novel strategy for the modulation of immunometabolic phenotype of fibroblast-like synoviocytes (FLS) –...

Call: OPUS 22 , Panel: NZ7

Principal investigator: prof. Krzysztof Marycz

Uniwersytet Przyrodniczy we Wrocławiu, Wydział Biologii i Hodowli Zwierząt

Electrospun nanofiber-based nanoplatform for delivery of new nutraceutical derivatives to eliminate chemotherapy-induced...

Call: OPUS 22 , Panel: NZ7

Principal investigator: dr hab. Maciej Wnuk

Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

Bifunctional, pH-responsive zeolite-bisphosphonates complex as a base for the production of smart bone implant for osteo...

Call: OPUS 22 , Panel: NZ7

Principal investigator: dr hab. Agata Przekora-Kuśmierz

Uniwersytet Medyczny w Lublinie, Wydział Biomedyczny

Translational and interdisciplinary investigation of phenotypes of reinforcement sensitivity as predictors of the respon...

Call: OPUS 22 , Panel: HS6

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Bioresorbable, electrospun nonwoven as a multi-drug delivery system for a combination glioblastoma therapy

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Monika Musiał-Kulik

Centrum Materiałów Polimerowych i Węglowych Polskiej Akademii Nauk

New strategies in the treatment of non-small cell lung cancer based on silk nanocarriers targeting tumor vascularization

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Anna Florczak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Targeting of HSF1 as a therapeutic approach to inhibit the progression of hormone-dependent breast cancer.

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr Natalia Vydra

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy, Oddział w Gliwicach

New immunomodulators of BTLA-HVEM complex as potential therapeutics in systemic lupus erythematosus

Call: OPUS 22 , Panel: NZ7

Principal investigator: dr hab. Anna Wardowska

Gdański Uniwersytet Medyczny, Wydział Lekarski

New post-treatment strategy against stroke and perinatal asphyxia – a novel approach based on a selective activation of ...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Agnieszka Wnuk

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk