Projects funded by the NCN

Design of coiled-coil and alpha/beta non-trivial protein folds that self-assemble in silico and in vitro.

Call: OPUS 28 , Panel: NZ1

Principal investigator: dr hab. Joanna Ida Sułkowska

Uniwersytet Warszawski

Clinical Variants of Hsp70 Chaperone HSPA1L in Protein Folding and Regulation of Glucocorticoid Receptor

Call: SONATA 20 , Panel: NZ5

Principal investigator: dr Agnieszka Antonina Kłosowska

Uniwersytet Gdański

Comprehensive structural and functional analysis of p53 mRNA to identify secondary and tertiary RNA structures important...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Leszek Michał Błaszczyk

Instytut Chemii Bioorganicznej PAN

Do beta cells fold up because of misfolding?

Call: PRELUDIUM 22 , Panel: NZ3

Principal investigator: Edyta Karolina Urbaniak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Co-translational protein folding in the light of ribosome evolution

Call: POLONEZ BIS 3 , Panel: NZ1

Principal investigator: dr Tomasz Włodarski

Instytut Biochemii i Biofizyki PAN

The role and physical properties of the 3-dimensional chromatin structure in the differentiation of hematopoietic cells ...

Call: PRELUDIUM BIS 3 , Panel: NZ2

Principal investigator: dr hab. Jakub Karol Mieczkowski

Gdański Uniwersytet Medyczny, Międzynarodowa Agenda Badawcza

Biological code of knots – identification of knotted patterns in biomolecules via AI approach

Call: OPUS 22 (LAP) , Panel: NZ1

Principal investigator: dr hab. Joanna Ida Sułkowska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Functional framework for viral RNA-dependent RNA polymerase, a major target in COVID19 treatment

Call: Polskie Powroty NAWA 2020 COVID-19 , Panel: NZ1

Principal investigator: dr Tomasz Wojciech Turowski

Instytut Biochemii i Biofizyki PAN

Cooperation between the extracytoplasmic protein quality control system and the Sec translocon in the process of protein...

Call: OPUS 20 , Panel: NZ2

Principal investigator: prof. Joanna Skórko-Glonek

Uniwersytet Gdański, Wydział Biologii

The role of 3D genome folding in the establishment of keratinocyte-specific promoter-enhancer network.

Call: OPUS 19 , Panel: NZ3

Principal investigator: dr hab. Michal Ryszard Gdula

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Understanding of human insulin maturation for cell and gene therapy in diabetes

Call: OPUS 19 , Panel: NZ3

Principal investigator: dr hab. Małgorzata Borowiak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Computational study of protein folding and dimerization on the ribosome

Call: OPUS 18 , Panel: ST4

Principal investigator: prof. Mai Suan Li

Instytut Fizyki PAN

Encapsidic production of difficult-to-express proteins

Call: OPUS 18 , Panel: NZ1

Principal investigator: dr Yusuke Azuma

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Synthetic self-assembled models of transmembrane proteins

Call: PRELUDIUM 18 , Panel: ST4

Principal investigator: Grzegorz Dawid Wołczański

Uniwersytet Wrocławski, Wydział Chemii

Hsp70 and its cochaperones in protein recovery from aggregates

Call: OPUS 18 , Panel: NZ1

Principal investigator: prof. Krzysztof Piotr Liberek

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Thermodynamic parameters and rules towards the determination of RNA folding in in vivo-like conditions. RNA folding pred...

Call: OPUS 17 , Panel: ST4

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej PAN

Characterisation of function and substrate binding of the prefoldin chaperone in physiology and cellular stress.

Call: OPUS 16 , Panel: NZ1

Principal investigator: dr Ulrike Topf

Instytut Biochemii i Biofizyki PAN

Sequence-defined macromolecules of controlled folding

Call: SONATA 14 , Panel: ST5

Principal investigator: dr Róża Szweda

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Thiol oxidoreductases of Helicobacter spp. - biochemical and structural characterization of the H. hepaticus Dsb system ...

Call: OPUS 15 , Panel: NZ1

Principal investigator: prof. Dariusz Bartosik

Uniwersytet Warszawski, Wydział Biologii

Increasing global and local accuracy of the coarse-grained UNRES model of proteins and its extensions to simulating very...

Call: OPUS 13 , Panel: ST4

Principal investigator: prof. Józef Adam Liwo

Uniwersytet Gdański, Wydział Chemii

Requirement of conserved folding catalysts in the functionality of several essential proteins, metabolic pathways and ke...

Call: OPUS 13 , Panel: NZ6

Principal investigator: prof. Satish Raina

Politechnika Gdańska, Wydział Chemiczny

Cotranscriptional folding of influenza virus RNA in MDCK cells in presence of antisense oligonucleotides. A new method f...

Call: OPUS 13 , Panel: NZ1

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej PAN

How RNA structure governs messenger RNA function? Exploring structural and functional aspects essential for synthesis of...

Call: SONATA 12 , Panel: NZ1

Principal investigator: dr Leszek Michał Błaszczyk

Instytut Chemii Bioorganicznej PAN

New tools and applications of NMR spectroscopy beyond resolution limitation

Call: MAESTRO 7 , Panel: ST4

Principal investigator: prof. Wiktor Adam Koźmiński

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Role of SWI/SNF remodeling complexes, CTCF1 protein , long non-coding RNA transcribed from BRCA1/NBR2 bidirectional prom...

Call: OPUS 6 , Panel: NZ2

Principal investigator: prof. Janusz Aleksander Siedlecki

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Structure and dynamics of protein chain at its folding temparature

Call: PRELUDIUM 3 , Panel: ST4

Principal investigator: Anna Maria Hałabis

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Structural and functional characterization of peptidyl prolyl isomerases - universally conserved protein folding catalys...

Call: OPUS 2 , Panel: NZ1

Principal investigator: prof. Satish Raina

Politechnika Gdańska, Wydział Chemiczny

Enhancing resolution and predictive power of the UNRES force field for protein folding simulations by revision of the po...

Call: PRELUDIUM 1 , Panel: ST4

Principal investigator: dr Adam Kazimierz Sieradzan

Uniwersytet Gdański, Wydział Chemii