Projects funded by the NCN

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47 projects found matching your search criteria :

  1. Synthesis, characteristics and activity of biopolymer-based modified magnetic nanoparticles as potential carriers for en...

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: dr hab. Michał Marszałł

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

  2. Selective activity based probes for imaging of active serine proteases in neutrophils.

    Call: HARMONIA 6 , Panel: ST5

    Principal investigator: dr hab. Marcin Drąg

    Politechnika Wrocławska, Wydział Chemiczny

  3. Design and synthesis of probes for RabGGTase profiling and their application for identification of the site of phosphono...

    Call: SONATA BIS 4 , Panel: ST5

    Principal investigator: dr hab. Katarzyna Błażewska

    Politechnika Łódzka, Wydział Chemiczny

  4. Multicommutated bioanalytical systems for kinetic studies and enzyme activity assays

    Call: OPUS 7 , Panel: ST4

    Principal investigator: prof. Robert Koncki

    Uniwersytet Warszawski, Wydział Chemii

  5. Role of the gates and anchoring residues in enzymes activity and selectivity.

    Call: SONATA BIS 3 , Panel: NZ1

    Principal investigator: dr Artur Góra

    Politechnika Śląska, Centrum Biotechnologii

  6. Investigation of the molecular mechanisms of anti-leukemic activity of SK053, a small molecule compound targeting enzyme...

    Call: SONATA BIS 3 , Panel: NZ5

    Principal investigator: prof. Dominika Nowis

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  7. Influence of chlorpyrifos on the activity of enzymes responsible for the vitamin D3 synthesis in skin cells

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: Krzysztof Sawicki

    Instytut Medycyny Wsi im. Witolda Chodźki

  8. The role of the brain serotonergic system in the expression and activity of liver cytochrome P450.

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: dr Marta Rysz

    Instytut Farmakologii, Polska Akademia Nauk

  9. Effect of confinement on the activity of single enzyme molecules encapsulated in liposome structure

    Call: SONATA 2 , Panel: ST4

    Principal investigator: dr Hubert Piwoński

    Instytut Chemii Fizycznej PAN

  10. Evaluating the antibacterial activity of the bacteriophage protein targeting Staphylococcus aureus, including drug-resis...

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Zuzanna Kaźmierczak

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  11. Unlocking nature's potential - exploring the ability of newly isolated from the environment bacteriophage and its enzyme...

    Call: PRELUDIUM 22 , Panel: NZ9

    Principal investigator: Aleksandra Łukasiak

    Uniwersytet Gdański, Wydział Biologii

  12. Development of a cell-based assay for screening of SARS-CoV-2 PLpro inhibitors

    Call: SONATA 18 , Panel: NZ6

    Principal investigator: dr Wioletta Rut

    Politechnika Wrocławska

  13. Fruits of Hylocereus polyrhizus clones as an alternative source of acylated betacyanin pigments in preparation of micros...

    Call: PRELUDIUM 20 , Panel: NZ9

    Principal investigator: Katarzyna Sutor-Świeży

    Politechnika Krakowska im. Tadeusza Kościuszki

  14. Involvement of vacuolar processing enzyme (VPE) and lipase in the degradation of autophagic bodies in cells embryo axes ...

    Call: PRELUDIUM 20 , Panel: NZ3

    Principal investigator: Szymon Stefaniak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  15. Assessment of changes in mitochondria and the activity of selected enzymes and mitochondrial proteins in freshwater shri...

    Call: PRELUDIUM 20 , Panel: NZ8

    Principal investigator: Anna Ostróżka

    Uniwersytet Śląski w Katowicach, Wydział Nauk Przyrodniczych

  16. Hybrid human SUMO proteins for selective detection and labelling of SENP proteases

    Call: OPUS 21 , Panel: ST4

    Principal investigator: dr Wioletta Rut

    Politechnika Wrocławska

  17. Role of roots of selected trees species in soil organic matter stabilization and in shaping microbial activity of forest...

    Call: PRELUDIUM 20 , Panel: NZ9

    Principal investigator: Karolina Staszel

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Leśny

  18. Chiroptical properties of proteins and their complexes (CRISPR/Cas-RNA), and their relationship to biological activity

    Call: SONATINA 5 , Panel: ST4

    Principal investigator: dr Monika Hałat

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Biotechnologii i Ogrodnictwa

  19. Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Paweł Siedlecki

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  20. Combined experimental and theoretical studies of the catalytic activity of RPE65 enzyme using biomimetic active centre m...

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Adam Kubas

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  21. Deadwood as microbial hotspots in mountain forest soils

    Call: OPUS 20 , Panel: NZ9

    Principal investigator: dr hab. Ewa Błońska

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Leśny

  22. Dissecting cancer activome to develop new generation of antibody-drug conjugates

    Call: OPUS 20 (LAP) , Panel: NZ5

    Principal investigator: dr hab. Marcin Poręba

    Politechnika Wrocławska

  23. Biotechnological potential and antimicrobial activity of biosurfactant-lipase conjugates immobilized on biopolymers

    Call: OPUS 19 , Panel: NZ9

    Principal investigator: dr Tomasz Janek

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Biotechnologii i Nauk o Żywności

  24. Application of voltammetry and gravimetry for simultaneous detection of matrix metalloproteinases -1, -2 and -9 in human...

    Call: OPUS 18 , Panel: ST4

    Principal investigator: dr hab. Anna Nowicka

    Uniwersytet Warszawski, Wydział Chemii

  25. The effects of carbamylation on the activity and biological function of Angiotensin I Converting Enzyme (ACE1)

    Call: PRELUDIUM 18 , Panel: NZ1

    Principal investigator: Marta Kamińska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  26. Design and synthesis of proteolytically stable and cell permeable activators of human 20S proteasome and assessing their...

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Elżbieta Jankowska

    Uniwersytet Gdański, Wydział Chemii

  27. Changes of the profile of fruits polyphenolic compounds under the influence of high pressure considering the activity of...

    Call: PRELUDIUM 17 , Panel: NZ9

    Principal investigator: Justyna Szczepańska

    Instytut Biotechnologii Przemysłu Rolno-Spożywczego im. prof. Wacława Dąbrowskiego

  28. Dietary polyphenols as thyroid peroxidase (TPO) modulators with multidirectional biological activity - a combined in vit...

    Call: OPUS 17 , Panel: NZ9

    Principal investigator: prof. Urszula Gawlik-Dziki

    Uniwersytet Przyrodniczy w Lublinie, Wydział Nauk o Żywności i Biotechnologii

  29. Characterization of hydrolysates and peptides derived from oat kernels proteins in the context of their activity in dise...

    Call: PRELUDIUM 16 , Panel: NZ9

    Principal investigator: dr Monika Pliszka

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauki o Żywności

  30. Search for structure-antimicrobial activity correlation for selected boraheterocycles

    Call: OPUS 16 , Panel: ST5

    Principal investigator: prof. Sergiusz Luliński

    Politechnika Warszawska, Wydział Chemiczny

  31. Structural and functional characterization of loci determining the content of cell wall-bound phenolics under the condit...

    Call: OPUS 16 , Panel: NZ9

    Principal investigator: dr hab. Tomasz Hura

    Instytut Fizjologii Roślin im. Franciszka Górskiego Polskiej Akademii Nauk

  32. Synthesis and characterization of new molecular probes for monitoring activity of enzymes associated with RNA decapping ...

    Call: OPUS 16 , Panel: ST5

    Principal investigator: dr hab. Joanna Kowalska

    Uniwersytet Warszawski, Wydział Fizyki

  33. Application of lanthanides in activity-based probes for the simultaneous detection of proteolytic enzymes.

    Call: HARMONIA 10 , Panel: ST5

    Principal investigator: prof. Marcin Drąg

    Politechnika Wrocławska

  34. Iron enzymes involved in biosynthesis of antibiotics - molecular activity mechanisms

    Call: OPUS 1 , Panel: ST4

    Principal investigator: prof. Ewa Brocławik

    POLSKA AKADEMIA UMIEJĘTNOŚCI

  35. CP protease of the O'nyong-nyong virus: substrate profiling, design and synthesis of inhibitors and activity-based probe...

    Call: OPUS 15 , Panel: NZ6

    Principal investigator: dr hab. Marcin Sieńczyk

    Politechnika Wrocławska

  36. Factors determining changes in enzymatic activity as well as the functional and genetic diveristy of microorganisms acro...

    Call: OPUS 15 , Panel: NZ9

    Principal investigator: prof. Anna Piotrowska-Długosz

    Politechnika Bydgoska im. Jana i Jędrzeja Śniadeckich, Wydział Rolnictwa i Biotechnologii

  37. Method of obtaining and biochemical characteristics of the nucleases from a psychrophilic microorganism Desulfotalea psy...

    Call: PRELUDIUM 1 , Panel: NZ1

    Principal investigator: Natalia Maciejewska

    Uniwersytet Gdański, Wydział Chemii

  38. New derivatives of clopidogrel - enantioselective biosynthesis and antiplatelet activity in vitro

    Call: PRELUDIUM 14 , Panel: NZ7

    Principal investigator: Adam Sikora

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

  39. New biocatalytic systems: carbon nanomaterial - enzyme, with controlled activity and potential application in anticancer...

    Call: PRELUDIUM 14 , Panel: ST5

    Principal investigator: Paulina Erwardt

    Uniwersytet Mikołaja Kopernika, Wydział Chemii

  40. Investigating the role of human tissue kallikreins in regulating matrix metalloproteinase activity.

    Call: PRELUDIUM 12 , Panel: NZ1

    Principal investigator: Katherine Falkowski

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  41. Differences in chitinolytic enzyme system of Bacillus cereus sensu lato as result of adaptation to ecologically distinct...

    Call: SONATA 12 , Panel: NZ8

    Principal investigator: dr Justyna Drewnowska

    Uniwersytet w Białymstoku, Wydział Biologii

  42. Soil biochemical properties and stabilization soil organic matter in relation to deadwood of different tree species

    Call: SONATA 11 , Panel: NZ9

    Principal investigator: dr hab. Ewa Błońska

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Leśny

  43. Modeling of catalytic activity of biological nanostructures - nonheme iron dioxygenases

    Call: PRELUDIUM 1 , Panel: ST4

    Principal investigator: dr Anna Wójcik

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  44. Novel MxOy-lignin hybrid materials as a multifunctional supports in enzyme immobilization process

    Call: PRELUDIUM 10 , Panel: ST8

    Principal investigator: Jakub Zdarta

    Politechnika Poznańska, Wydział Technologii Chemicznej

  45. Reversible modification of enzyme activity and substrate specificity by engineering of the ligand exchange pathways

    Call: HARMONIA 7 , Panel: NZ1

    Principal investigator: dr Artur Góra

    Politechnika Śląska, Centrum Biotechnologii

  46. Study on the kinetics inactivation of selected plant enzymes from oxidoreductase group by using supercritical carbon dio...

    Call: SONATA 9 , Panel: NZ9

    Principal investigator: dr Krystian Marszałek

    Instytut Biotechnologii Przemysłu Rolno-Spożywczego im. prof. Wacława Dąbrowskiego

  47. Impact of high hydrostatic pressure on the profile of bioactive compounds, antioxidant activity, enzyme and microbial st...

    Call: OPUS 9 , Panel: NZ9

    Principal investigator: dr hab. Wioletta Błaszczak

    Instytut Rozrodu Zwierząt i Badań Żywności PAN

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