Projects funded by the NCN

Identification of cytochrome P450 isoenzymes involved in the metabolism of levomepromazine in the human

Call: OPUS 1 , Panel: NZ4

Principal investigator: dr hab. Jacek Wójcikowski

Instytut Farmakologii PAN

The effect of typical and atypical neuroleptics on the expression of cytochrome P450 isoenzymes 1A2 (CYP1A2) and 3A4 (CY...

Call: PRELUDIUM 8 , Panel: NZ7

Principal investigator: Agnieszka Basińska-Ziobroń

Instytut Farmakologii PAN

Changes in the proteome of the filamentous fungus Cunninghamella echinulata during degradation of organic tin compounds

Call: PRELUDIUM 7 , Panel: NZ9

Principal investigator: Adrian Soboń

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

The effect of the novel atypical neuroleptics on the activity and expression of cytochrome P450 isoforms in human liver

Call: OPUS 6 , Panel: NZ7

Principal investigator: dr hab. Jacek Wójcikowski

Instytut Farmakologii PAN

Investigation of amino acid linker-specific dependence of electron transfer between cytochrome c553 and photosystem I fr...

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: Julian Janna Olmos

Uniwersytet Warszawski, Wydział Biologii

The significance of the serotonergic innervation of the brain hypothalamus in the regulation of cytochrome P450

Call: OPUS 6 , Panel: NZ7

Principal investigator: prof. Władysława Daniel

Instytut Farmakologii PAN

Genetic structure of common vole and field vole populations in Poland: comparisons of museum and contemporary samples.

Call: PRELUDIUM 5 , Panel: NZ8

Principal investigator: Joanna Stojak

Instytut Biologii Ssaków PAN

Influence of chlorpyrifos on the activity of enzymes responsible for the vitamin D3 synthesis in skin cells

Call: PRELUDIUM 5 , Panel: NZ7

Principal investigator: Krzysztof Sawicki

Instytut Medycyny Wsi im. Witolda Chodźki

The role of the brain serotonergic system in the expression and activity of liver cytochrome P450.

Call: PRELUDIUM 4 , Panel: NZ7

Principal investigator: dr Marta Rysz

Instytut Farmakologii, Polska Akademia Nauk

Studies on the mechanism regulating expression of hormone-dependent cytochromes P450 in the rat liver under conditions o...

Call: PRELUDIUM 4 , Panel: NZ4

Principal investigator: Rafał Skowronek

Śląski Uniwersytet Medyczny w Katowicach, Wydział Lekarski w Katowicach

The influence of the serotonergic system on the regulation of liver CYP activity in hepatocellular carcinoma

Call: SONATA 4 , Panel: NZ4

Principal investigator: dr Marta Kot

Instytut Farmakologii PAN

The tRNA/cytochrome C complex formation and its role in programmed cell death

Call: OPUS 1 , Panel: NZ3

Principal investigator: dr hab. Arkadiusz Chworoś

Centrum Badań Molekularnych i Makromolekularnych PAN

Evaluation of the synthesis and metabolism modulation of estrogens - breast cancer risk factors by new synthetic resvera...

Call: OPUS 3 , Panel: NZ7

Principal investigator: prof. Wanda Baer-Dubowska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Helicobacter pylori Dsb (disulfide bond) proteins - analysis of the relations between sequence, structure and function o...

Call: OPUS 3 , Panel: NZ1

Principal investigator: prof. Elżbieta Jagusztyn-Krynicka

Uniwersytet Warszawski, Wydział Biologii

The study on the mechanism of vitamin D analogues anticancer action in combination with anastrozole in a human breast ca...

Call: PRELUDIUM 3 , Panel: NZ4

Principal investigator: Beata Filip-Psurska

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

The effect of prolonged treatment with the new antipsychotics brexpiprazole and lumateperone on human liver function usi...

Call: OPUS 26 , Panel: NZ4

Principal investigator: dr Przemysław Danek

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Molecular mechanism and quantum effects associated with electron and proton transfer in primary steps of quinone-depende...

Call: OPUS 25 , Panel: NZ1

Principal investigator: dr hab. Marcin Sarewicz

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The thylakoid soluble phosphoprotein 9 (TSP9) as a novel partner of plant cytochrome b6f - exploring dynamics of its int...

Call: OPUS 24 , Panel: NZ1

Principal investigator: prof. Artur Osyczka

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Brain cytochrome P450 as a new target for the treatment of neurological and psychiatric diseases. Studies with human neu...

Call: OPUS 23 , Panel: NZ7

Principal investigator: prof. Władysława Daniel

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Extremophilic archaea bioenergetics: respiratory oxidoreductases structure and function in Sulfolobus acidocaldarius

Call: SONATA 17 , Panel: NZ1

Principal investigator: dr Sebastian Pintscher

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The triangle: carotenoids-retinoids-cytochromes plays a key role in development and progress of cancer

Call: OPUS 22 , Panel: ST4

Principal investigator: prof. Halina Abramczyk

Politechnika Łódzka

The role of intestinal CYP2E1 in pathophysiology of the gastrointestinal tract disorders: new therapies for leaky gut sy...

Call: PRELUDIUM BIS 3 , Panel: NZ7

Principal investigator: dr hab. Maciej Sałaga

Uniwersytet Medyczny w Łodzi

The molecular basis behind ROS production by cytochrome bc1: involvement of redox potentials of heme cofactors

Call: PRELUDIUM 20 , Panel: NZ1

Principal investigator: Jakub Pagacz

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Identifying the routes of electron transfer in respiratory alternative complex III by mutational and biochemical studies

Call: PRELUDIUM 20 , Panel: NZ1

Principal investigator: Katarzyna Lorencik

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The effect of chronic treatment with iasenapine and iloperidone on the expression and activity of cytochrome P450 in the...

Call: PRELUDIUM 16 , Panel: NZ7

Principal investigator: dr Przemysław Danek

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Design and optimisation of molecular interface for efficient electron transfer within photosystem I-based photovoltaic d...

Call: OPUS 14 , Panel: ST5

Principal investigator: dr hab. Joanna Kargul

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

The role of brain glutamatergic system in the neuroendocrine regulation of cytochrome P450 expression and activity in th...

Call: OPUS 12 , Panel: NZ7

Principal investigator: prof. Władysława Daniel

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Mechanism of interaction between carbon nanoparticles of diamond, graphene oxide and graphite and cytochrome P450 enzyme...

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Barbara Strojny

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Wydział Nauk o Zwierzętach

The molecular effects of human mitochondrial cytochrome b mutations studied in bacterial Rhodobacter capsulatus cytochro...

Call: OPUS 11 , Panel: NZ1

Principal investigator: dr Arkadiusz Borek

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Molecular basis of regulation of electron flow between membranous quinone and water-soluble cytochrome. Does mitochondri...

Call: MAESTRO 7 , Panel: NZ1

Principal investigator: prof. Artur Osyczka

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Porphyrazine based catalyst support for biomimetic studies on selected active pharmaceutical ingredients

Call: PRELUDIUM 9 , Panel: NZ7

Principal investigator: Tomasz Koczorowski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Studies on influence of cytochrome c on oxidative damage of 2-thiouridines built in an RNA chain

Call: PRELUDIUM 9 , Panel: ST5

Principal investigator: Anna Chwiałkowska

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk