Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of intestinal CYP2E1 in pathophysiology of the gastrointestinal tract disorders: new therapies for leaky gut syndrome and inflammatory bowel diseases

2021/43/O/NZ7/01273

Keywords:

cytochrome CYP2E1 inflammatory bowel diseases leaky gut syndrome intesitnal barrier

Descriptors:

  • NZ4_004:
  • NZ7_014:
  • NZ5_003:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny w Łodzi

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Maciej Stawnisław Sałaga 

Number of co-investigators in the project: 2

Call: PRELUDIUM BIS 3 - announced on 2021-09-15

Amount awarded: 565 920 PLN

Project start date (Y-m-d): 2022-10-01

Project end date (Y-m-d): 2026-09-30

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Role of Cytochromes P450 in Intestinal Barrier Function: Possible Involvement in the Pathogenesis of Leaky Gut Syndrome
    Authors:
    Adam Makaro · Zuzanna Kasprzak · Maria Jaczynska · Mikolaj Swierczynski · Maciej Salaga
    Academic press:
    Digestive Diseases and Sciences (rok: 2025, tom: Online ahead of print., strony: Online ahead of print.), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10620-025-08873-8 - link to the publication