Projects funded by the NCN

Light-producing, oxygen-delivering, cancer cell-targeted carriers for photosensitisers dedicated for photodynamic therap...

Call: OPUS 22 , Panel: NZ7

Principal investigator: prof. Marek Murias

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a...

Call: OPUS 22 , Panel: NZ7

Principal investigator: prof. Katarzyna Kieć-Kononowicz

Uniwersytet Jagielloński, Collegium Medicum

Searching for the mechanisms inducing improvement in motor function and prolonging the lifespan in amyotrophic lateral s...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Damian Flis

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Katarzyna Kucwaj-Brysz

Uniwersytet Jagielloński, Collegium Medicum

Photoswitchable and chimeric molecules for spatially restricted and endoplasmic reticulum-specific blockade of PD-L1 pro...

Call: SONATA BIS 11 , Panel: NZ7

Principal investigator: dr Łukasz Skalniak

Uniwersytet Jagielloński, Wydział Chemii

RE-SENSE: Dual-loaded lipid nanoparticles to overcome the resistance of non-small cell lung cancer cells to personalized...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Mikołaj Czajkowski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Identification of breast cancer cells death and senescence mechanisms induction resulting from telomerase silencing with...

Call: OPUS 2 , Panel: NZ7

Principal investigator: dr hab. Błażej Rubiś

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Bioabsorbable hydroxyapatite/polymer nanocomposite granules with enhanced osteoconductivity and anti-inflammatory proper...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Vladyslav Vivcharenko

Uniwersytet Medyczny w Lublinie

Normalization of energy metabolism as a way to develop innovative antithrombotic therapies

Call: OPUS 21 , Panel: NZ7

Principal investigator: dr Patrycja Kaczara

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

In search for molecular targets to overcome doxorubicin resistance in triple-negative breast cancer with the use of inno...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Anna Pogorzelska

Narodowy Instytut Leków

Benchmarking Human Tissue Culture Systems that Mimic the Tumor Microenvironment

Call: OPUS 21 , Panel: NZ7

Principal investigator: prof. Matthias Nees

Uniwersytet Medyczny w Lublinie

An innovative method of treating acute liver failure using amniotic stem cells isolated from the human placenta.

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Patrycja Wieczorek

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Molecular mechanism of the protective effect of swimming training on skeletal muscle atrophy and the course of amyotroph...

Call: OPUS 20 , Panel: NZ7

Principal investigator: prof. Wiesław Ziółkowski

Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Instytutem Medycyny Morskiej i Tropikalnej

A novel approach based on the optimized multidrug combination for glioblastoma treatment.

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Małgorzata Kucińska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Identification of potential markers aiming early diagnostics of progression and tailoring metastasis-oriented therapies ...

Call: OPUS 20 , Panel: NZ5

Principal investigator: dr Natalia Bednarz-Knoll

Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Electroporation-based manipulation of drug resistance in cancer using novel nanosecondasymmetrical pulse sequences

Call: DAINA 2 , Panel: NZ7

Principal investigator: dr hab. Julita Kulbacka

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny

The effect of methylated resveratrol analogue 3,4,4',5-tetramethoxystilbene (DMU-212) on secretion profile and different...

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Małgorzata Józkowiak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Modern nanoparticle and model organism - a toxic relation? Physiological and cellular causes of developmental disorders ...

Call: OPUS 19 , Panel: NZ7

Principal investigator: prof. Maria Augustyniak

Uniwersytet Śląski w Katowicach, Wydział Nauk Przyrodniczych

Assessment of the ability of application of folic acid and/or transferrin as alinkers between conjugates of quantum dots...

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Joanna Pilch

Politechnika Gdańska

Deciphering progression of triple negative breast cancer – analysis of tumor-associated cells in the bloodstream using s...

Call: OPUS 19 , Panel: NZ7

Principal investigator: dr hab. Anna Żaczek

Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

Call: OPUS 19 , Panel: NZ7

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Gamma-glutamylcysteine ligase participation in the antioxidant mechanism of action of sulodexide on vascular endothelial...

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Klaudia Bontor

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Molecular mechanisms of interplay between RORγ/RORγT receptors and cyclin-dependent kinase inhibitor (AT7519). Analysis ...

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Kaja Karaś

Instytut Biologii Medycznej Polskiej Akademii Nauk

Evaluation of molecular mechanisms of neuroprotective action of dental pulp stromal cells in an ex vivo organotypic mode...

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Natalia Bryniarska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Design and synthesis of proteolytically stable and cell permeable activators of human 20S proteasome and assessing their...

Call: PRELUDIUM BIS 1 , Panel: NZ7

Principal investigator: dr hab. Elżbieta Jankowska

Uniwersytet Gdański, Wydział Chemii

Chemical architecture of fluorinated nucleoside dimers containing 1,2,3-triazole linker of potential use in molecular bi...

Call: SONATA 15 , Panel: NZ7

Principal investigator: dr Dagmara Baraniak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

The role of kappa opioid receptors during chronic intestinal inflammation and colitis-associated colorectal cancer – foc...

Call: SONATA 15 , Panel: NZ7

Principal investigator: dr Marta Zielińska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Effect of adipose-derived stem cells on in vitro cultured skin cells obtained from patients undergoing chemotherapy.

Call: OPUS 17 , Panel: NZ7

Principal investigator: dr hab. Michał Pikuła

Gdański Uniwersytet Medyczny, Wydział Lekarski

Nasal administration of probiotics - development of an allergic rhinitis in vitro model and the assessment of probiotic ...

Call: PRELUDIUM 17 , Panel: NZ7

Principal investigator: Marcelina Pyclik

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Specific interactions of new antitumor unsymmetrical bisacridines, UAs, with DNA and ABC proteins and their potential to...

Call: OPUS 17 , Panel: NZ7

Principal investigator: prof. Zofia Mazerska

Politechnika Gdańska

Targeting of hypoxic cancer cells for imaging

Call: OPUS 17 , Panel: NZ7

Principal investigator: dr hab. Małgorzata Brindell

Uniwersytet Jagielloński, Wydział Chemii

The anti-inflammatory effect of vitamin K - Mechanism of action

Call: PRELUDIUM 16 , Panel: NZ7

Principal investigator: dr Anna Kierońska-Rudek

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Dissecting of the novel mechanisms in multi-drug resistance associated with vault's proteins and translation initiation ...

Call: SONATA BIS 8 , Panel: NZ7

Principal investigator: dr hab. Witold Szaflarski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

MicroRNAs in blood as biomarkers for Alzheimer's disease: molecular signature for personalized therapy

Call: OPUS 15 , Panel: NZ7

Principal investigator: prof. Urszula Wojda

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Towards novel mechanisms of endothelial dysfunction in E3L.CETP mice displaying hyperlipidaemia with human-like lipoprot...

Call: OPUS 15 , Panel: NZ7

Principal investigator: prof. Stefan Chłopicki

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

How microglia-astrocyte interaction affects neuronal functioning in the dopaminergic system. Analysis of the protective ...

Call: OPUS 14 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Kuter-Nowak

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Structure and function of human erythrocyte membrane exposed to selected brominated flame retardants (in vitro)

Call: PRELUDIUM 14 , Panel: NZ7

Principal investigator: Monika Jarosiewicz

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

7,8-disubstituted theophylline derivatives that are potent inhibitors of selected PDE isoenzymes as a new compounds with...

Call: OPUS 14 , Panel: NZ7

Principal investigator: dr Katarzyna Wójcik-Pszczoła

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Modulation of inflammatory processes using new agonists of the formyl peptide receptors ALX/FPR2 as a new therapeutic st...

Call: HARMONIA 9 , Panel: NZ7

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Combined urinary bladder cancer treatment with isothiocyanate-derived mercapturic acids and microtubule assembly modulat...

Call: SONATA 13 , Panel: NZ7

Principal investigator: dr Mateusz Psurski

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

New usnic acid derivatives as anticancer therapeutics

Call: HARMONIA 9 , Panel: NZ7

Principal investigator: prof. Anna Herman-Antosiewicz

Uniwersytet Gdański, Wydział Biologii

The role of MCPIP1 as a potential tumor suppressor during development and treatment of clear cell renal cell carcinoma

Call: PRELUDIUM 13 , Panel: NZ5

Principal investigator: dr Paulina Marona

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Modification of the DNA helix structure by newly synthesized cytotoxic compound (Cl-IPBD) in selected cancer cell lines ...

Call: PRELUDIUM 13 , Panel: NZ7

Principal investigator: dr Dominika Janiszek

Uniwersytet Warszawski, Wydział Chemii

Model of lipid nanoagregates transport by epitelial cells with additional steps of pharmacokinetic

Call: PRELUDIUM 13 , Panel: NZ7

Principal investigator: Kamila Szostak-Paluch

Politechnika Wrocławska

Evaluation of nervous system cells homeostasis in the experimental in vitro model of cobalamin deficiency as an approach...

Call: PRELUDIUM 13 , Panel: NZ7

Principal investigator: Zuzanna Rzepka

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Farmaceutycznych w Sosnowcu

The forced oscillation technique in patients with non-small cell lung cancer after thoracic surgery subjected to an earl...

Call: PRELUDIUM 12 , Panel: NZ7

Principal investigator: dr Sabina Kostorz-Nosal

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Zabrzu

Molecular background of brain metastases in lung cancer

Call: SONATA 12 , Panel: NZ2

Principal investigator: dr Marcin Nicoś

Uniwersytet Medyczny w Lublinie, Wydział Lekarski

Synthesis, toxicological and functional studies on mutli-walled carbon nanotubes as a scaffold for tissue engineering te...

Call: OPUS 12 , Panel: NZ7

Principal investigator: prof. Michał Giersig

Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

Mathematical modelling of drug resistance in anticancer therapies.

Call: PRELUDIUM 12 , Panel: ST1

Principal investigator: dr Mariusz Bodzioch

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Matematyki i Informatyki

Solid phase microextraction-based universal analytical platform for assessment of in vitro generated metabolism

Call: PRELUDIUM 12 , Panel: NZ7

Principal investigator: Karol Jaroch

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny