Projects funded by the NCN


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101 projects found matching your search criteria :

  1. Immunogenicity assessment of dimeric tick-borne encephalitis virus E protein in mRNA and virus-like particles-based anti...

    Call: PRELUDIUM 24 , Panel: NZ6

    Principal investigator: Klaudia Katarzyna Barańska

    Uniwersytet Gdański

  2. Development of the fluorescence multifunctional biosensing system based on antisense oligonucleotide probes for the onco...

    Call: PRELUDIUM 24 , Panel: ST4

    Principal investigator: Hubert Grzegorz Grel

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

  3. Molecular Pathogenesis and Precision Antisense Oligonucleotide Therapy for BAG3-Related Myofibrillar Myopathy Type 6 Usi...

    Call: OPUS 29 , Panel: NZ2

    Principal investigator: dr Estera Elmira Rintz

    Uniwersytet Gdański

  4. Elimination of IgE-producing cells using next-generation chimeric antigen receptor (CAR)-based therapy

    Call: OPUS 29 , Panel: NZ6

    Principal investigator: dr hab. Beata Kaleta

    Warszawski Uniwersytet Medyczny

  5. New approach to glioblastoma adoptive therapy based on inducible CAR expression system - SynCAR

    Call: OPUS 29 , Panel: NZ6

    Principal investigator: dr hab. Radosław Zagożdżon

    Warszawski Uniwersytet Medyczny

  6. Chemical synthesis, immunological evaluation and epitope analysis of carbohydrate antigens of Pseudomonas aeruginosa

    Call: SHENG 4 , Panel: NZ6

    Principal investigator: prof. Jolanta Katarzyna Łukasiewicz

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  7. Identification of novel antigens of Borrelia miyamotoi and their significance in the differential diagnosis of Lyme borr...

    Call: OPUS 28 , Panel: NZ6

    Principal investigator: dr hab. Renata Anna Welc-Falęciak

    Uniwersytet Warszawski

  8. Trichinella spiralis and Trichinella britovi multi-antigen vaccine - a new approach to prevent trichinellosis

    Call: SONATA 20 , Panel: NZ6

    Principal investigator: dr Anna Beata Stachyra

    Warszawski Uniwersytet Medyczny

  9. Invisible Bonds: The Social and Relationship Implications of Human Leukocyte Antigen (HLA) Compatibility

    Call: MAESTRO 16 , Panel: HS6

    Principal investigator: prof. S. Craig Roberts

    Uniwersytet Wrocławski

  10. The Potential of Mycobacterium tuberculosis Phase-Specific Antigens for Targeted TB Diagnosis

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr Shima Mahmoudi

    Politechnika Śląska

  11. Decoding novel O/K loci of Klebsiella pneumoniae into chemical O/K antigen structures – towards better adjustment of bac...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Jolanta Katarzyna Łukasiewicz

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  12. Evolution of Major Histocompatibility Complex (MHC) genes and pathogen antigens, induced by adaptive immune response and...

    Call: OPUS 27 , Panel: NZ8

    Principal investigator: dr Maciej Jan Ejsmond

    Uniwersytet Jagielloński

  13. Interrogation of the antigen presentation dynamics via MHCII in tumor immune evasion through multimodal single-cell sequ...

    Call: SONATINA 8 , Panel: NZ2

    Principal investigator: dr Natalia Ochocka-Lewicka

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  14. Exploring kinase hyperactivation as an innovative approach for chemo-immunotherapy for B cell acute lymphoblastic leukem...

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  15. Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficac...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  16. Heterogeneity immunocompetent cells during chimeric antigen receptor T cell (CAR-T) CD19 immunotherapy.

    Call: PRELUDIUM 22 , Panel: NZ6

    Principal investigator: Aleksandra Maria Oszer

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  17. Antisense oligonucleotides as tools specifically binding viral G-quadruplexes and their experimental verification

    Call: OPUS 25 , Panel: ST4

    Principal investigator: dr Marta Maria Szabat

    Instytut Chemii Bioorganicznej PAN

  18. Novel monovalent and multivalent recombinant proteins of Borrelia burgdorferi sensu lato as potential antigens for the d...

    Call: OPUS 25 , Panel: NZ6

    Principal investigator: dr hab. Lucyna Holec-Gąsior

    Politechnika Gdańska, Wydział Chemiczny

  19. The role of genome architecture and related chromatin modifications in innate immune transcriptional memory of antigen p...

    Call: Polskie Powroty NAWA 2022 , Panel: NZ2

    Principal investigator: dr Paweł Sławomir Mikulski

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk - Imol

  20. Uncovering the molecular background of equine erythrocyte antigens variability using serological and genetic methods

    Call: OPUS 24 , Panel: NZ9

    Principal investigator: dr hab. Jakub Łukasz Cieślak

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  21. Condition-dependent mechanisms of gamete-level mate choice (postmating sexual selection) in humans

    Call: OPUS 24 , Panel: NZ8

    Principal investigator: dr Aleksandra Łukasiewicz

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  22. The discovery of multifactorial regulation at epigenetic memory of active gene expression state

    Call: SONATA 18 , Panel: NZ2

    Principal investigator: dr Paweł Sławomir Mikulski

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  23. Role of HIV antisense transcripts in the establishment of latency: genome-wide map antisense RNAs to understand how they...

    Call: SONATA BIS 12 , Panel: NZ6

    Principal investigator: dr Heng-Chang Chen

    Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

  24. Retrogenes as important players in cancer regulatory pathways

    Call: PRELUDIUM 21 , Panel: NZ2

    Principal investigator: Klaudia Halina Staszak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  25. Elements of the HLA class I antigen processing machinery as factors involved inthe pathomechanism and progression of end...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr hab. Izabela Nowak

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  26. P-stereodefined phosphorothioate analogs of morpholino" oligonucleotides (sTMO) as a new model of therapeutic nucleic ac...

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Katarzyna Jastrzębska

    Centrum Badań Molekularnych i Makromolekularnych PAN

  27. Role of antisense oligonucleotide-induced intronic microRNA on axonal morphogenesis in zebrafish

    Call: SONATA 17 , Panel: NZ3

    Principal investigator: dr Savani Anbalagan

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  28. Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec...

    Call: OPUS 21 , Panel: NZ1

    Principal investigator: prof. Elżbieta Beata Kierzek

    Instytut Chemii Bioorganicznej PAN

  29. Mechanisms of immunity directed against coronaviruses based on theanalysis of antibodies in convalescents, exposed/sub-c...

    Call: OPUS 20 , Panel: NZ6

    Principal investigator: prof. Piotr Bogumił Heczko

    Uniwersytet Jagielloński, Collegium Medicum

  30. Immunogenicity of plant-produced chimeric Virus-Like Particles formed byHBcAg displaying HBsAg epitopes for potential th...

    Call: POLS , Panel: NZ7

    Principal investigator: dr Benita Ortega Berlanga

    Instytut Genetyki Roślin PAN

  31. Increasing the precision of chimeric antigen receptor (CAR)-mediated anticancer immunotherapy by using the chemokine-ind...

    Call: OPUS 19 , Panel: NZ6

    Principal investigator: dr hab. Radosław Zagożdżon

    Warszawski Uniwersytet Medyczny

  32. Immune response induced by injection-oral co-immunisation with plant-derived HBV antigens polarising the response to Th1...

    Call: OPUS 19 , Panel: NZ6

    Principal investigator: dr hab. Tomasz Jan Pniewski

    Instytut Genetyki Roślin PAN

  33. Antisense oligonucleotides and their nanostructures conjugated with boron clusters; physico-chemical and biological char...

    Call: ETIUDA 8 , Panel: ST4

    Principal investigator: Damian Mateusz Kaniowski

    Centrum Badań Molekularnych i Makromolekularnych PAN

  34. Participation of cellular proteins in the inhibition of antigen presentation dependent on UL49.5 protein of bovine herpe...

    Call: ETIUDA 8 , Panel: NZ3

    Principal investigator: Magda Dominika Wąchalska

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  35. Optical imaging of the antigen specific lymphocyte responses within the entire lymph nodes.

    Call: ETIUDA 8 , Panel: NZ6

    Principal investigator: Paweł Matryba

    Warszawski Uniwersytet Medyczny

  36. Elucidating the role and mechanism of regulatory network of genes encodingdioxygenases in terms of plant adaptation to l...

    Call: PRELUDIUM BIS 1 , Panel: NZ1

    Principal investigator: prof. Ewa Łojkowska

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  37. Analysis of the connection between endosomal-lysosomal system deregulation and the antigen presentation process mediated...

    Call: PRELUDIUM 18 , Panel: NZ3

    Principal investigator: Katarzyna Maria Zima

    Uniwersytet Gdański, Wydział Biologii

  38. Host sex effect on immunity and protection after oral immunization with Fasciola hepatica cysteine protease and the para...

    Call: OPUS 18 , Panel: NZ6

    Principal investigator: dr hab. Małgorzata Joanna Kęsik-Brodacka

    Narodowy Instytut Leków

  39. Investigation on PD-L1 biology for precise shaping of anticancer adoptive therapies

    Call: SONATA 15 , Panel: NZ6

    Principal investigator: dr Agnieszka Graczyk-Jarzynka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  40. Hijacking the ubiquitin-proteasome system by the UL49.5 protein of bovine herpesvirus 1 as an immune evasion strategy – ...

    Call: PRELUDIUM 18 , Panel: NZ6

    Principal investigator: dr Magda Dominika Wąchalska

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  41. Smart antigen provision for efficient induction of allergen tolerance

    Call: SONATA BIS 9 , Panel: NZ6

    Principal investigator: dr hab. Danuta Katarzyna Gutowska-Owsiak

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  42. The role of the oxidative stress in adoptive cell therapy with chimeric antigen receptors

    Call: OPUS 17 , Panel: NZ6

    Principal investigator: dr Małgorzata Agnieszka Bajor

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  43. Nontypeable Klebsiella pneumoniae O antigens - structure and seroepidemiology

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Jolanta Katarzyna Łukasiewicz

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  44. Avian homologues of the human P1PK blood group antigens: how birds nullify Shiga toxins despite expressing a functional ...

    Call: OPUS 16 , Panel: NZ6

    Principal investigator: prof. Marcin Eugeniusz Czerwiński

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  45. Uncovering novel secondary seed dormancy regulators in Arabidopsis

    Call: OPUS 16 , Panel: NZ3

    Principal investigator: dr Ruslan Yatusevich

    Instytut Biochemii i Biofizyki PAN

  46. Bet-hedging in plants - multi level analysis of seed dormancy variability - from singel cell to population

    Call: SONATA BIS 8 , Panel: NZ1

    Principal investigator: dr Szymon Świeżewski

    Instytut Biochemii i Biofizyki PAN

  47. The role of microbiota-triggered antigen stimulation in development and progression of chronic lymphocytic leukemia

    Call: OPUS 15 , Panel: NZ5

    Principal investigator: prof. Krzysztof Giannopoulos

    Uniwersytet Medyczny w Lublinie, II Wydział Lekarski z Oddziałem Anglojęzycznym

  48. Immunogenic properties of hepatitis C virus NS3 protein epitopes fused to hepatitis B small surface antigen

    Call: OPUS 14 , Panel: NZ6

    Principal investigator: dr Katarzyna Monika Grzyb

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  49. The structure and biological role of Bifidobacterium components in allergy disease development.

    Call: SONATA BIS 7 , Panel: NZ7

    Principal investigator: dr Sabina Barbara Górska

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  50. Metagenomic analysis of bacteriomiome and mycobiome of the digestive tract in children and adolescents and their healthy...

    Call: SONATA BIS 7 , Panel: NZ5

    Principal investigator: dr hab. Tomasz Gosiewski

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum