Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Investigation on PD-L1 biology for precise shaping of anticancer adoptive therapies

2019/35/D/NZ6/03073

Keywords:

PD-L1 chimeric antigen receptors immunotherapy tumor microenvironment

Descriptors:

  • NZ6_2: Clinical immunology
  • NZ6_1: Adaptive and innate immunity

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk, I Wydział Lekarski

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Agnieszka Graczyk-Jarzynka 

Number of co-investigators in the project: 4

Call: SONATA 15 - announced on 2019-09-16

Amount awarded: 1 624 380 PLN

Project start date (Y-m-d): 2020-07-08

Project end date (Y-m-d): 2025-07-07

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells.
    Authors:
    Malgorzata Bajor, Agnieszka Graczyk-Jarzynka, Katsiaryna Marhelava, Anna Burdzinska, Angelika Muchowicz, Agnieszka Goral, Andriy Zhylko, Karolina Soroczynska, Kuba Retecki, Marta Krawczyk, Marta Klopotowska, Zofia Pilch, Leszek Paczek, Karl-Johan Malmberg, Sébastien Wälchli, Magdalena Winiarska Radoslaw Zagozdzon
    Academic press:
    Journal for ImmunoTherapy of Cancer (rok: 2022, tom: 10(1):e002500, strony: 39), Wydawca: BMJ journals
    Status:
    Published
    DOI:
    10.1136/jitc-2021-002500 - link to the publication
  2. PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells.
    Authors:
    Malgorzata Bajor, Agnieszka Graczyk-Jarzynka, Katsiaryna Marhelava, Anna Burdzinska, Angelika Muchowicz, Agnieszka Goral, Andriy Zhylko, Karolina Soroczynska, Kuba Retecki, Marta Krawczyk, Marta Klopotowska, Zofia Pilch, Leszek Paczek, Karl-Johan Malmberg, Sébastien Wälchli, Magdalena Winiarska Radoslaw Zagozdzon
    Academic press:
    Journal for ImmunoTherapy of Cancer (rok: 2022, tom: 10(1):e002500, strony: 39), Wydawca: BMJ journals
    Status:
    Published
    DOI:
    10.1136/jitc-2021-002500 - link to the publication
  3. PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells.
    Authors:
    Malgorzata Bajor, Agnieszka Graczyk-Jarzynka, Katsiaryna Marhelava, Anna Burdzinska, Angelika Muchowicz, Agnieszka Goral, Andriy Zhylko, Karolina Soroczynska, Kuba Retecki, Marta Krawczyk, Marta Klopotowska, Zofia Pilch, Leszek Paczek, Karl-Johan Malmberg, Sébastien Wälchli, Magdalena Winiarska Radoslaw Zagozdzon
    Academic press:
    Journal for ImmunoTherapy of Cancer (rok: 2022, tom: 10(1):e002500, strony: 39), Wydawca: BMJ journals
    Status:
    Published
    DOI:
    10.1136/jitc-2021-002500 - link to the publication

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