Projects funded by the NCN

Comprehensive analysis of the therapeutic potential of oligonucleotides for the treatment of polyglutamine diseases

Call: SONATA 9 , Panel: NZ5

Principal investigator: dr hab. Agnieszka Fiszer

Instytut Chemii Bioorganicznej PAN

The use of chemically modified antisense oligonucleotides in the experimental therapy against Myotonic Dystrophy (DM).

Call: OPUS 8 , Panel: NZ5

Principal investigator: dr Ewa Stepniak-Konieczna

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

RNA hybrid duplex-quadruplex structures with dual functionality as a new tool for silecing of gene expression

Call: OPUS 7 , Panel: ST5

Principal investigator: prof. Zofia Gdaniec

Instytut Chemii Bioorganicznej PAN

Exploring the Mutual Interactions between RNA Enantiomers

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: Marta Dudek

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Modified chlorophyll derivatives and its RNA hybrid conjugates for modern photomedicine

Call: PRELUDIUM 6 , Panel: NZ7

Principal investigator: Michał Kotkowiak

Politechnika Poznańska, Wydział Fizyki Technicznej

Structure defined oligonucleotides for revealing fundamental insights into structure and function of RNAs

Call: MAESTRO 4 , Panel: ST5

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej PAN

Conserved RNA structural motifs in influenza virus: toward revealing viral RNA functions

Call: HARMONIA 4 , Panel: NZ1

Principal investigator: dr hab. Elżbieta Kierzek

Instytut Chemii Bioorganicznej PAN

Multitasking polymeric lattices included selected DNA oligonucleotide sequences - synthesis, modifications and physioche...

Call: SONATA 3 , Panel: ST5

Principal investigator: dr Ewelina Zabost

Uniwersytet Warszawski, Wydział Chemii

New approaches towards modulating selective and functional activities of antisense oligonucleotides

Call: OPUS 2 , Panel: ST5

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej PAN

(Micro)RNA and informatics approaches for diagnosis, prognosis and treatment of Alzheimer's disease and Dementia

Call: JPND Call 2023 , Panel: NZ3

Principal investigator: dr hab. Agnieszka Fiszer

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Antisense oligonucleotides as tools specifically binding viral G-quadruplexes and their experimental verification

Call: OPUS 25 , Panel: ST4

Principal investigator: dr Marta Szabat

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec...

Call: OPUS 21 , Panel: NZ1

Principal investigator: prof. Elżbieta Kierzek

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRN...

Call: SONATA 16 , Panel: ST4

Principal investigator: dr Dorota Gudanis

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Synthesis and structural studies of oligonucleotides with tRNA anticodon stem-loop sequences containing newly discovered...

Call: OPUS 13 , Panel: ST5

Principal investigator: prof. Elżbieta Sochacka

Politechnika Łódzka, Wydział Chemiczny

Structural determinants of anticancer properties of G-rich oligonucleotides

Call: OPUS 13 , Panel: NZ7

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Cotranscriptional folding of influenza virus RNA in MDCK cells in presence of antisense oligonucleotides. A new method f...

Call: OPUS 13 , Panel: NZ1

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Double stranded probes, in which both oligonucleotide components hybridize according to the Hoogsteen's interactions, an...

Call: OPUS 10 , Panel: ST5

Principal investigator: dr hab. Piotr Guga

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

Chromatographic determination of nucleic acids (DNA, RNA) and their constituents (nucleosides, nucleotides, oligonuceoti...

Call: SONATA 1 , Panel: ST4

Principal investigator: dr Sylwia Studzińska

UNIWERSYTET MIKOŁAJA KOPERNIKA, Wydział Chemii, Katedra Chemii Środowiska i Bioanalityki

In vivo and in vitro structure of influenza virus RNA. The structural determinants behind the inhibition of influenza vi...

Call: OPUS 10 , Panel: NZ1

Principal investigator: prof. Elżbieta Kierzek

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk