Projects funded by the NCN

The development of classic and aggregation- induced emission activity- based probes for human caspases.

Call: PRELUDIUM 13 , Panel: ST5

Principal investigator: Katarzyna Groborz

Politechnika Wrocławska

An integrated screening platform for determination of human proteasomes extended substrate specificity

Call: OPUS 13 , Panel: ST5

Principal investigator: prof. Marcin Drąg

Politechnika Wrocławska

SLPI-dependent cutaneous antimicrobial and antiviral immunity.

Call: OPUS 13 , Panel: NZ6

Principal investigator: prof. Joanna Cichy

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The structural and functional characterization of Tpr, calpain-like peptidase and important virulence factor of Porphyro...

Call: PRELUDIUM 13 , Panel: NZ1

Principal investigator: dr Dominika Staniec

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Allosteric inhibitors of proteasome - optimization of the structure of PR39 analogs in order to achieve greater efficien...

Call: PRELUDIUM 12 , Panel: ST5

Principal investigator: Małgorzata Giżyńska

Uniwersytet Gdański, Wydział Chemii

Evaluation of primary and secondary molecular disorders determinig drug resistance from a group of proteasome inhibitors...

Call: OPUS 12 , Panel: NZ5

Principal investigator: prof. Tadeusz Robak

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

SLPI - novel regulator involved in the neuro-immune interplay in psoriasis

Call: SONATA 12 , Panel: NZ6

Principal investigator: dr Beata Grygier

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Investigating the role of human tissue kallikreins in regulating matrix metalloproteinase activity.

Call: PRELUDIUM 12 , Panel: NZ1

Principal investigator: Katherine Falkowski

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Autophagy and ubiquitin-proteasome system as potential mechanisms responsible for left ventricle mass loss in a monocrot...

Call: PRELUDIUM 12 , Panel: NZ5

Principal investigator: Mateusz Hołda

Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Lekarski

The effect of crowded environment on the catalytic activity and dynamics of viral proteases

Call: OPUS 12 , Panel: NZ1

Principal investigator: prof. Joanna Trylska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

In vivo role of transient ECM protease activity in synaptic plasticity

Call: PRELUDIUM 11 , Panel: NZ3

Principal investigator: Marta Magnowska

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Physiological characterization of the HtrA4 protease, including its role in apoptosis.

Call: PRELUDIUM 11 , Panel: NZ3

Principal investigator: dr Tomasz Wenta

Uniwersytet Gdański, Wydział Biologii

Zika virus NS3 protease

Call: OPUS 11 , Panel: NZ6

Principal investigator: dr hab. Krzysztof Pyrć

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Structure and function characterization of newly discovered unique inhibitors of proteases

Call: OPUS 11 , Panel: NZ1

Principal investigator: prof. Jan Potempa

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The role of the HtrA protein in the Helicobacter pylori cell

Call: OPUS 11 , Panel: NZ2

Principal investigator: prof. Joanna Skórko-Glonek

Uniwersytet Gdański, Wydział Biologii

The link between mitochondria and the protein quality control system

Call: POLONEZ 2 , Panel: NZ3

Principal investigator: dr Michał Turek

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Analysis of quality control of peroxisomes depending on chaperon, protease and autophagy

Call: POLONEZ 2 , Panel: NZ9

Principal investigator: dr Shino Yamada

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Using X-ray crystallography for localization of the sites of binding of allosteric inhibitors and activators within the ...

Call: PRELUDIUM 9 , Panel: NZ1

Principal investigator: Julia Witkowska

Uniwersytet Gdański, Wydział Chemii

Investigation of the antitumor potential of stimulator of interferon genes (STING) - an adaptor protein in innate immune...

Call: PRELUDIUM 9 , Panel: NZ6

Principal investigator: Olga Sokołowska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Insight into biochemistry, structure, evolution and biology of bacterial serpins on example of miropin from human pathog...

Call: OPUS 9 , Panel: NZ1

Principal investigator: dr Mirosław Książek

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Understanding the mechanism of ubiquitin-mediated proteolysis of the MAPKKK18 kinase

Call: PRELUDIUM 9 , Panel: NZ3

Principal investigator: Małgorzata Tajdel-Zielińska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Combinatorial peptide libraries modified by ionization tags on solid support for investigation of new substrates of prot...

Call: SONATA 9 , Panel: ST5

Principal investigator: dr Remigiusz Bąchor

Uniwersytet Wrocławski, Wydział Chemii