Projects funded by the NCN


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67 projects found matching your search criteria :

  1. Dual cell cycle blockade and immune checkpoint inhibition as a potential strategy of sequential anticancer therapy

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Alicja Stanisława Słota

    Uniwersytet Jagielloński

  2. Targeted Degradation of the MLL Complex in Leukemia: A PROTAC-Based Therapeutic Strategy

    Call: SONATINA 9 , Panel: ST5

    Principal investigator: dr Natalia Anna Skrzypczak

    Fundacja Uniwersytetu im. Adama Mickiewicza

  3. Where Inhibition is not Enough- Development of Innovative Compounds for Targeted Degradation of Extracellular and Membra...

    Call: OPUS 28 (LAP) , Panel: NZ5

    Principal investigator: dr Marcin Skoreński

    Politechnika Wrocławska

  4. Development of cIAP1-targeting CDK4/6 degraders (PROTACs) containing a phosphoroorganic warhead (POWERTAP)

    Call: SONATA 20 , Panel: NZ3

    Principal investigator: dr Agnieszka Łupicka-Słowik

    Politechnika Wrocławska

  5. FA-PROTACs - Design and Synthesis of Compounds Based on Folic Acid for Degradation of Enzyme Involved in Folate Metaboli...

    Call: SONATA 20 , Panel: NZ5

    Principal investigator: dr Mateusz Daśko

    Politechnika Gdańska

  6. Polyphosphate condensates in regulation of proteases' localization and activity in stressed Escherichia coli cells

    Call: PRELUDIUM 23 , Panel: NZ1

    Principal investigator: Zuzanna Karolina Hirsz

    Uniwersytet Gdański

  7. Targeting Proteinopathies: Understanding and Mitigating the Effects of Pathogenic Mutations in Cullin-RING Ubiquitin Lig...

    Call: OPUS 27 , Panel: NZ3

    Principal investigator: dr hab. Wojciech Mieczysław Pokrzywa

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  8. PROteolysis TArgeting Chimeras (PROTACs) intended to knock down excessive amyloidogenic proteins, human islet amyloid po...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr hab. Elżbieta Jankowska

    Uniwersytet Gdański, Wydział Chemii

  9. The role of extracytoplasmic proteases in the physiology and morphology of the bacterium Helicobacter pylori

    Call: SONATA 19 , Panel: NZ2

    Principal investigator: dr Urszula Zarzecka

    Uniwersytet Gdański, Wydział Biologii

  10. Macrocyclic peptides for targeting of membrane-anchored serine protease

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Paulina Maria Kasperkiewicz-Wasilewska

    Politechnika Wrocławska

  11. µPPET: studying the Cosmic Rays Muon Puzzle by probing muons with J-PETs

    Call: SONATA BIS 13 , Panel: ST9

    Principal investigator: dr Alessio Porcelli

    Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  12. Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficac...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  13. Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  14. Analysis of functional and taxonomic diversity of symbionts among euglenozoan protists

    Call: POLONEZ BIS 3 , Panel: NZ8

    Principal investigator: dr Daria Tashyreva

    Uniwersytet Warszawski, Wydział Biologii

  15. Biological membranes and macromolecular crowding in the function of the hepatitis C virus proteases

    Call: PRELUDIUM BIS 4 , Panel: NZ1

    Principal investigator: prof. Joanna Dominika Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  16. A double whammy for the NF-κB signalling pathway: development of TAK1 and IKKβ degraders against inflammation-driven dis...

    Call: OPUS 24 (LAP) , Panel: NZ7

    Principal investigator: dr hab. Anna Karolina Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  17. Role of neutrophil serine proteases in chronic inflammatory skin diseases associated with Regnase-1 malfunction

    Call: OPUS 23 , Panel: NZ6

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  18. Machine learning, big data, and the cross-section of stock returns in international markets

    Call: OPUS 23 , Panel: HS4

    Principal investigator: dr hab. Adam Zaremba

    Uniwersytet Ekonomiczny w Poznaniu, Instytut Finansów

  19. Demetallization of sewage sludges towards obtaining the feedstocks for theproduction of safe digestates and composts

    Call: SONATA 17 , Panel: NZ9

    Principal investigator: dr Anna Siatecka

    Uniwersytet Przyrodniczy w Lublinie, Wydział Nauk o Żywności i Biotechnologii

  20. Impact of the CDK4/6 targeted degradation by PROTACs on immune checkpoint signaling in cancer

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr Katarzyna Magiera-Mularz

    Uniwersytet Jagielloński, Wydział Chemii

  21. Investigation of the MLK4 biology in breast cancer and search for new therapeutic strategies using innovative PROTAC com...

    Call: SONATA BIS 11 , Panel: NZ5

    Principal investigator: dr Anna Agnieszka Marusiak

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  22. The structures, biochemistry, physiology, and evolution of bacterial α2-macroglobulins from the human periodontopathogen...

    Call: SONATA BIS 11 , Panel: NZ1

    Principal investigator: dr Mirosław Książek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  23. Role of DPPIV family proteases in transposon silencing and genome maintenance

    Call: SONATA BIS 11 , Panel: NZ1

    Principal investigator: dr Rajani Kanth Gudipatti

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  24. Cross-Sectional Properties of Cryptocurrency Returns

    Call: OPUS 21 , Panel: HS4

    Principal investigator: dr hab. Barbara Zofia Będowska-Sójka

    Uniwersytet Ekonomiczny w Poznaniu, Instytut Informatyki i Ekonomii Ilościowej

  25. Hybrid human SUMO proteins for selective detection and labelling of SENP proteases

    Call: OPUS 21 , Panel: ST4

    Principal investigator: dr Wioletta Katarzyna Rut

    Politechnika Wrocławska

  26. The role of neutrophil serine proteases in the regulation of function of the podocyte and glomerular filtration barrier.

    Call: OPUS 21 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  27. The role of extracellular proteases – yapsins – in gaining pathogenic advantage by Candida glabrata in the host organism...

    Call: SONATA 16 , Panel: NZ6

    Principal investigator: dr Dorota Anna Satała

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  28. Application of PROTAC strategy for controlling Rab geranylgeranyl transferase and Rab proteins

    Call: PRELUDIUM BIS 2 , Panel: ST4

    Principal investigator: dr hab. Katarzyna Magdalena Błażewska

    Politechnika Łódzka, Wydział Chemiczny

  29. Mountain ecosystems facing global warming: study of impact of snow cover parameters on microbial communities of nivicolo...

    Call: OPUS 20 (LAP) , Panel: NZ8

    Principal investigator: dr hab. Anna Małgorzata Ronikier

    Instytut Botaniki im. Władysława Szafera PAN

  30. Targeted degradation of Rab geranylgeranyl transferase as a new approach to investigate prenylation of Rab GTPases

    Call: PRELUDIUM BIS 2 , Panel: NZ1

    Principal investigator: dr hab. Edyta Violetta Gendaszewska-Darmach

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  31. Defining the interplay between SLPI and the IL-1 family cytokines in the immune response

    Call: SONATA 16 , Panel: NZ6

    Principal investigator: dr Ewa Małgorzata Oleszycka

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  32. Neutrophils heterogeneity based on serine proteases

    Call: SONATA BIS 10 , Panel: NZ3

    Principal investigator: dr Paulina Maria Kasperkiewicz-Wasilewska

    Politechnika Wrocławska

  33. Role of cereal leaf beetle – associated bacteria in the adaptation of their insect host to the insecticides and protease...

    Call: PRELUDIUM 19 , Panel: NZ9

    Principal investigator: dr Beata Wielkopolan

    Instytut Ochrony Roślin - Państwowy Instytut Badawczy

  34. Particle production and their correlations in high energy collisions.

    Call: POLS , Panel: ST2

    Principal investigator: dr Anderson Kendi Ramidan Kohara

    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Fizyki i Informatyki Stosowanej

  35. Molecular mechanism underlying the anti-inflammatory action of CB2 receptor agonists in microglia: participation of the ...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr Natalia Eleonora Małek-Chudzik

    Politechnika Wrocławska

  36. Impact of models for multiparton interactions in proton-proton collisions at LHC energies for the prediction of radiatio...

    Call: PRELUDIUM BIS 1 , Panel: ST2

    Principal investigator: dr hab. Agnieszka Magdalena Obłąkowska-Mucha

    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Fizyki i Informatyki Stosowanej

  37. Characterization of two novel proteases from the human periodontopathogen Tannerella forsythia

    Call: PRELUDIUM 16 , Panel: NZ1

    Principal investigator: Irena Maria Waligórska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  38. Nuclear fragmentation cross section measurements for comic rays

    Call: BEETHOVEN 3 , Panel: ST2

    Principal investigator: dr hab. Seweryn Kowalski

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

  39. Cellular proteases during coronaviral infection

    Call: OPUS 14 , Panel: NZ6

    Principal investigator: dr hab. Krzysztof Pyrć

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  40. SLPI-dependent cutaneous antimicrobial and antiviral immunity.

    Call: OPUS 13 , Panel: NZ6

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  41. SLPI - novel regulator involved in the neuro-immune interplay in psoriasis

    Call: SONATA 12 , Panel: NZ6

    Principal investigator: dr Beata Katarzyna Grygier

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  42. New, promising catalyst for green production of propylene oxide from propane or propene

    Call: OPUS 12 , Panel: ST5

    Principal investigator: dr Agnieszka Held

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  43. Investigating the role of human tissue kallikreins in regulating matrix metalloproteinase activity.

    Call: PRELUDIUM 12 , Panel: NZ1

    Principal investigator: Katherine Monique Falkowski

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  44. The cross-section of stock returns in frontier emerging markets

    Call: OPUS 12 , Panel: HS4

    Principal investigator: dr Adam Zaremba

    Uniwersytet Ekonomiczny w Poznaniu, Instytut Finansów

  45. Development of the adiabatic variational theory for cold atom-diatomic molecule collision experiments

    Call: SONATA 12 , Panel: ST4

    Principal investigator: dr Mariusz Pawlak

    Uniwersytet Mikołaja Kopernika, Wydział Chemii

  46. The effect of crowded environment on the catalytic activity and dynamics of viral proteases

    Call: OPUS 12 , Panel: NZ1

    Principal investigator: prof. Joanna Dominika Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  47. Structure and function characterization of newly discovered unique inhibitors of proteases

    Call: OPUS 11 , Panel: NZ1

    Principal investigator: prof. Jan Stanisław Potempa

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  48. An impact of climate change (warming and drought) on biodiversity of micro-eukaryotes in peatlands - next generation seq...

    Call: PRELUDIUM 10 , Panel: NZ8

    Principal investigator: Monika Katarzyna Reczuga

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Nauk Geograficznych i Geologicznych

  49. Femur structural analysis: reconstruction of human mobility from Palaeolithic to modern times.

    Call: PRELUDIUM 10 , Panel: NZ8

    Principal investigator: Anna Maria Kubicka

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  50. A Cross-section in Time: The Church of the Holy Virgin in Deir al-Surian - an integrated analysis of the building, its p...

    Call: HARMONIA 7 , Panel: HS3

    Principal investigator: dr hab. Dobrochna Zielińska

    Uniwersytet Warszawski, Wydział Archeologii