Projects funded by the NCN

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21 projects found matching your search criteria :

  1. Dual-acting 5-HT6/5-HT7 receptor antagonists: exploring beneficial effects for the treatment of neurodegenerative disord...

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Michał Kamiński

    Uniwersytet Jagielloński

  2. Modulation of 5-HT7 receptor signaling as common mechanism involved in the long-lasting antidepressant effects of typica...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Barbara Wanda Chruścicka-Smaga

    Instytut Farmakologii PAN

  3. Dual Se-containing 5-HT1A and 5-HT7 biased agonists activating sigma-1 receptor as a hope of finding fast-acting antidep...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Karolina Anna Pytka

    Uniwersytet Jagielloński

  4. Targeting the serotonin 5-HT7 receptor in a search for new strategies of mental disorders treatment

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Patryk Pyka

    Uniwersytet Jagielloński, Collegium Medicum

  5. Molecular mechanisms of 5-HT7R-mediated resilience in stress-related disorders

    Call: OPUS 21 , Panel: NZ4

    Principal investigator: prof. Jakub Mateusz Włodarczyk

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  6. The place does matter - 5-HT7R-mediated structural plasticity in the specific hippocampal subregions

    Call: SONATA 15 , Panel: NZ4

    Principal investigator: dr Monika Bijata

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  7. Therapeutic potential of biased 5-HT7 receptor ligands in the treatment of depression

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: prof. Paweł Maria Zajdel

    Uniwersytet Jagielloński, Collegium Medicum

  8. Development of a comprehensive set of computational tools for the search of new ligands of particular receptor - case st...

    Call: OPUS 16 , Panel: NZ2

    Principal investigator: dr hab. Sabina Marta Podlewska

    Instytut Farmakologii PAN

  9. Development of a group of non-basic ligands of serotonin receptor 5-HT7, derivatives of 2-(6-oxo-3-phenyl-1,6-dihydropyr...

    Call: SONATINA 2 , Panel: NZ7

    Principal investigator: dr Sabina Marta Podlewska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  10. Development of unique molecular probes: low-basicity agonists for the study of 5-HT7 receptor function

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Andrzej Jacek Bojarski

    Instytut Farmakologii PAN

  11. Anilide derivatives of long-chain cyclic amines as multifunctional serotonin receptors ligands and phosphodiesterase 7 i...

    Call: PRELUDIUM 13 , Panel: NZ7

    Principal investigator: dr Agnieszka Wioleta Jankowska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  12. The role of codependent 5-HT1a and 5-HT7 receptor signalling in the hippocampal stress response

    Call: PRELUDIUM 12 , Panel: NZ4

    Principal investigator: Marcin Siwiec

    Instytut Farmakologii PAN

  13. Modulation of amygdala neural network activity by the 5-HT7 receptor

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Krzysztof Tokarski

    Instytut Farmakologii PAN

  14. Searching for the new lead structures for 5-HT7 serotonin receptor ligands with increased metabolic stability.

    Call: HARMONIA 7 , Panel: NZ7

    Principal investigator: Sabina Marta Podlewska

    Instytut Farmakologii PAN

  15. Amine derivatives of hydantoin as selective 5-HT7 receptor ligand. Molecular modeling, synthesis and pharmacological eva...

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Katarzyna Maria Kucwaj-Brysz

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum Uniwersytet Jagielloński; Wydział Farmaceutyczny

  16. The influence of 5-HT7 and NMDA receptor ligands with possible antidepressive properties on the activity of rat dorsal r...

    Call: OPUS 6 , Panel: NZ4

    Principal investigator: prof. Grzegorz Władysław Hess

    Instytut Farmakologii PAN

  17. The role of dystroglycan in synaptic plasticity modulated by small Rho GTPases

    Call: PRELUDIUM 5 , Panel: NZ3

    Principal investigator: Monika Bijata

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  18. Synthesis and pharmacological properties of mono- di- and triheterocyclic azole derivatives as a hybrid receptor and PDE...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: prof. Maciej Henryk Pawłowski

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  19. Probing the selectivity of zinc allosteric modulation in various serotonin receptor subtypes

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Grzegorz Marek Satała

    Instytut Farmakologii PAN

  20. LCAP biomimetics - alicyclic amine derivatives as a new class of monoaminergic receptor ligands

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: dr hab. Paweł Maria Zajdel

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  21. In the search for active compounds among ligands of serotonin, particularly 5-HT7, and dopamine receptors, with potentia...

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: prof. Anna Małgorzata Wesołowska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

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