Projects funded by the NCN

Unusual 5-HT6 receptor ligands

Call: OPUS 7 , Panel: NZ7

Principal investigator: prof. Andrzej Bojarski

Instytut Farmakologii PAN

First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Jadwiga Handzlik

Uniwersytet Jagielloński, Collegium Medicum

Combination of FAAH inhibition with action via serotonin 5-HT6 receptor as pioneering approach to fight with Alzheimer D...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Kinga Czarnota-Łydka

Uniwersytet Jagielloński, Collegium Medicum

Dual 5-HT3 receptor/5-HT6 receptor antagonists in neuropsychiatric and neurological disorders

Call: OPUS 22 , Panel: NZ7

Principal investigator: prof. Paweł Zajdel

Uniwersytet Jagielloński, Collegium Medicum

New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl...

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Przemysław Zaręba

Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

Towards innovative strategy for treatment of Alzheimer's Disease via dual inhibition of receptor 5-HT6 and kinase CDK5.

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Sylwia Sudoł

Uniwersytet Jagielloński, Collegium Medicum

Neuroprotective properties of 5-HT6 receptor ligands in the group of 2-arylpyrrole derivatives – a new insight into neur...

Call: PRELUDIUM 17 , Panel: NZ7

Principal investigator: Marcin Drop

Uniwersytet Jagielloński, Collegium Medicum

Thymol-derived 1,3,5-triazines, the non-indole and non-sulfone 5-HT6 receptor ligands, as a starter in search for an inn...

Call: OPUS 16 , Panel: NZ7

Principal investigator: prof. Jadwiga Handzlik

Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Novel hybrid 5-HT6 serotonin receptor and SERT transporter ligands as a therapeutic perspective of behavioural and cogni...

Call: SONATA 14 , Panel: NZ7

Principal investigator: dr Agata Siwek

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Novel multi-target directed ligands combining cholinesterase inhibition and 5-HT6 antagonism - design, synthesis and pha...

Call: SONATA 12 , Panel: NZ7

Principal investigator: dr hab. Anna Więckowska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

The role of halogen bonding in interaction of ligands with SERT.

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr Jakub Staroń

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Biased inverse agonists of 5-HT6 receptor and dual 5-HT6/MAO-B inhibitors - in search for new therapeutic approaches for...

Call: OPUS 11 , Panel: NZ7

Principal investigator: prof. Paweł Zajdel

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

The determination of ADME-Tox in vitro for potential CNS-drug candidates acting as potent and selective ligands of serot...

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Annamaria Lubelska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

5-HT6 receptor ligands as addition to antipsychotic therapy in schizophrenia - an impact on body weight, metabolic param...

Call: OPUS 10 , Panel: NZ7

Principal investigator: prof. Anna Wesołowska

Uniwersytet Jagielloński Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Traizine 5-HT6 receptor ligands - new perspective for therapy of current civilization CNS-diseases

Call: OPUS 9 , Panel: NZ7

Principal investigator: dr hab. Jadwiga Handzlik

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny