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Keywords: small molecule inhibitor

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16 projects found matching your search criteria:

1. Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu…

Principal investigator: dr Magdalena Wujak

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

Call: OPUS 26, Panel: NZ7
2. Innovative Small Molecule Inhibitors Targeting LAG-3 and MHCII Complex for Tumour Immunotherapy

Principal investigator: dr Jacek Plewka

Uniwersytet Jagielloński

Call: OPUS 27, Panel: NZ7
3. Small-molecule inhibitors of protein aggregation and ER stress as a novel strategy against neurodegeneration in the cour…

Principal investigator: prof. Ireneusz Jacek Majsterek

Uniwersytet Medyczny w Łodzi

Call: PRELUDIUM BIS 3, Panel: NZ5
4. Exploring Baltic Sea cyanobacteria for small-molecule inhibitors of microRNA function

Principal investigator: prof. Paweł Michał Brzuzan

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Geoinżynierii

Call: OPUS 13, Panel: NZ9
5. Transient protein states in designing small-molecule inhibitors of protein-protein interactions

Principal investigator: prof. Tadeusz Andrzej Holak

Uniwersytet Jagielloński, Wydział Chemii

Call: SYMFONIA 2, Panel: NZ1
6. Use of novel small molecule inhibitors of PERK kinase dependent UPR pathway for the colorectal cancer treatment

Principal investigator: prof. Adam Janusz Dziki

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: OPUS 12, Panel: NZ5
7. Use of novel small molecule inhibitors of PERK kinase dependent UPR pathway for the primary open-angle glaucoma treatmen…

Principal investigator: prof. Ireneusz Jacek Majsterek

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: OPUS 11, Panel: NZ5
8. Disrupting the Toxic NMDAR/TRPM4 Protein Dialogue as a Novel Neuroprotective Strategy: Development of Small-Molecule Inh…

Principal investigator: Katarzyna Aleksandra Szafrańska

Uniwersytet Jagielloński

Call: PRELUDIUM 24, Panel: NZ7
9. Development of dual immuno-oligo- biosensors for monitoring and controlling of the metastatic colorectal cancer and inve…

Principal investigator: dr hab. Magdalena Stobiecka

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

Call: OPUS 25, Panel: ST4
10. Small-molecule inhibitors for characterization of the interaction between extracellular domains of Programmed Cell Death…

Principal investigator: prof. Tadeusz Andrzej Holak

Uniwersytet Jagielloński, Wydział Chemii

Call: MAESTRO 9, Panel: ST5
11. Understanding the mechanism of action for small molecule kinase inhibitors in alleviating myotonic dystrophy type 1 (DM1…

Principal investigator: dr hab. Marzena Wojciechowska

Instytut Chemii Bioorganicznej PAN

Call: OPUS 7, Panel: NZ5
12. Discovery and development of small-molecule inhibitors of USP2 for targeted, non-genotoxic therapy of cancer

Principal investigator: prof. Tadeusz Andrzej Holak

Uniwersytet Jagielloński, Wydział Chemii

Call: OPUS 1, Panel: ST5
13. Investigation of the molecular mechanisms of anti-leukemic activity of SK053, a small molecule compound targeting enzyme…

Principal investigator: prof. Dominika Anna Nowis

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: SONATA BIS 3, Panel: NZ5
14. The SAR analysis and synthesis of complex, small molecule PD-1/PD-L1 interaction antagonists

Principal investigator: Magdalena Maria Żarnik

Uniwersytet Jagielloński, Wydział Chemii

Call: PRELUDIUM 20, Panel: ST4
15. Cell-based high-throughput screening for small-molecule compounds diminishing molecular markers of pathogenesis in myoto…

Principal investigator: dr hab. Marzena Wojciechowska

Instytut Chemii Bioorganicznej PAN

Call: OPUS 20, Panel: NZ3
16. Compounds modulating function of telomeric proteins TRF1 and TRF2

Principal investigator: prof. Maciej Wojciech Bagiński

Politechnika Gdańska, Wydział Chemiczny

Call: OPUS 25, Panel: NZ7

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